Acetylleucine-chloromethyl-ketone

General

Type : Peptide

Chemical_Nomenclature : N-[(3S)-1-chloro-5-methyl-2-oxohexan-3-yl]acetamide

Canonical SMILES : CC(C)CC(C(=O)CCl)NC(=O)C

InChI : InChI=1S\/C9H16ClNO2\/c1-6(2)4-8(9(13)5-10)11-7(3)12\/h6,8H,4-5H2,1-3H3,(H,11,12)\/t8-\/m0\/s1\

InChIKey : JVCMEFWIVFRFTB-QMMMGPOBSA-N

Other name(s) : ALCK,Ac-Leu-CH2Cl


MW : 205.68z

Formula : C9H16ClNO2

CAS_number :

PubChem : 10242067

UniChem : JVCMEFWIVFRFTB-QMMMGPOBSA-N

IUPHAR :

Wikipedia :

Target

Families : Acetylleucine-chloromethyl-ketone ligand of proteins in family: ACPH_Peptidase_S9

Stucture :

Protein : human-APEH

References (1)

Title : Acetylleucine chloromethyl ketone, an inhibitor of acylpeptide hydrolase, induces apoptosis of U937 cells - Yamaguchi_1999_Biochem.Biophys.Res.Commun_263_139
Author(s) : Yamaguchi M , Kambayashi D , Toda J , Sano T , Toyoshima S , Hojo H
Ref : Biochemical & Biophysical Research Communications , 263 :139 , 1999
Abstract : Yamaguchi_1999_Biochem.Biophys.Res.Commun_263_139
ESTHER : Yamaguchi_1999_Biochem.Biophys.Res.Commun_263_139
PubMedSearch : Yamaguchi_1999_Biochem.Biophys.Res.Commun_263_139
PubMedID: 10486267