Inhibitor

Bibliography

Biblio print

Tree Display

AceDB Schema

XML Display

Feedback

Inhibitor Report for: CHEMBL4069230


General
Type: Sulfur Compound, Naphthalen
Chemical_Nomenclature: N-[4-[(4-naphthalen-2-yloxyphenyl)sulfamoyl]phenyl]acetamide
Canonical SMILES: CC(=O)NC1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)OC3=CC4=CC=CC=C4C=C3
InChI: InChI=1S/C24H20N2O4S/c1-17(27)25-20-9-14-24(15-10-20)31(28,29)26-21-7-12-22(13-8-21)30-23-11-6-18-4-2-3-5-19(18)16-23/h2-16,26H,1H3,(H,25,27)
InChIKey: YYGHDFIKAKVWFF-UHFFFAOYSA-N
Other name(s): 8U0 ; AC1LOBCX ; ZINC991941 ; STK256902
MW: 432.5
Formula: C24H20N2O4S
CAS_number:
PubChem: 1217803
IUPHAR:
Wikipedia:

Target families
CHEMBL4069230 ligand of proteins in family: PAF-Acetylhydrolase

Stucture of targets
1 structure:
5YE7: The crystal structure of Lp-PLA2 in complex with a novel inhibitor

Protein target
Enzyme: human-PLA2G7

References
Search PubMed for references concerning: CHEMBL4069230
    Title: Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2
    Liu Q, Huang F, Yuan X, Wang K, Zou Y, Shen J, Xu Y
    Ref: Journal of Medicinal Chemistry, 60:10231, 2017 : PubMed