Chloroalkane-Cyanine3-fluorophore
General
Type : Indole,HaloTag-ligand,Cyanide
Chemical_Nomenclature : ~{N}-[2-[2-(6-chloranylhexoxy)ethoxy]ethyl]-6-[3,3-dimethyl-2-[(~{E})-3-(1,3,3-trimethylindol-2-ylidene)prop-1-enyl]indol-1-ium-1-yl]hexanamide
Canonical SMILES : CC1(c2ccccc2[N+](=C1\/C=C\/C=C3C(c4ccccc4N3C)(C)C)CCCCCC(=O)NCCOCCOCCCCCCCl)C
InChI : InChI=1S\/C40H56ClN3O3\/c1-39(2)32-18-10-12-20-34(32)43(5)36(39)22-17-23-37-40(3,4)33-19-11-13-21-35(33)44(37)27-15-8-9-24-38(45)42-26-29-47-31-30-46-28-16-7-6-14-25-41\/h10-13,17-23H,6-9,14-16,24-31H2,1-5H3\/p+1
InChIKey : PMDIAZIQXAWRGJ-UHFFFAOYSA-O
Other name(s) : PJI
MW : 663.35
Formula : C40H57ClN3O3
CAS_number :
PubChem :
UniChem : PMDIAZIQXAWRGJ-UHFFFAOYSA-O
IUPHAR :
Wikipedia :
Target
Families : Chloroalkane-Cyanine3-fluorophore ligand of proteins in family: Haloalkane_dehalogenase-HLD2
Stucture : 8B6R X-ray structure of the haloalkane dehalogenase HaloTag7 labeled with a chloroalkane Cyanine3 fluorophore substrate
Protein : rhoso-halo1
References (1)
| Title : A general method for the development of multicolor biosensors with large dynamic ranges - Hellweg_2023_Nat.Chem.Biol__ |
| Author(s) : Hellweg L , Edenhofer A , Barck L , Huppertz MC , Frei MS , Tarnawski M , Bergner A , Koch B , Johnsson K , Hiblot J |
| Ref : Nat Chemical Biology , : , 2023 |
| Abstract : Hellweg_2023_Nat.Chem.Biol__ |
| ESTHER : Hellweg_2023_Nat.Chem.Biol__ |
| PubMedSearch : Hellweg_2023_Nat.Chem.Biol__ |
| PubMedID: 37291200 |
| Gene_locus related to this paper: rhoso-halo1 |