Kaempferol
Kaempferol is a natural flavonoid which has been isolated from Delphinium, Witch-hazel, grapefruit...
General
Type : Natural,Flavonoid
Chemical_Nomenclature : 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one
Canonical SMILES : C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O
InChI : InChI=1S\/C15H10O6\/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15\/h1-6,16-18,20H
InChIKey : IYRMWMYZSQPJKC-UHFFFAOYSA-N
Other name(s) : Kempferol,Kaempherol,Robigenin,CHEBI:28499,ChEMBL150
MW : 286.24
Formula : C15H10O6
CAS_number : 520-18-3
PubChem : 5280863
UniChem : IYRMWMYZSQPJKC-UHFFFAOYSA-N
IUPHAR :
Wikipedia : Kaempferol
Target
References (11)
| Title : Kaempferol as a therapeutic agent in Alzheimer's disease: Evidence from preclinical studies - Dong_2023_Ageing.Res.Rev_87_101910 |
| Author(s) : Dong X , Zhou S , Nao J |
| Ref : Ageing Res Rev , 87 :101910 , 2023 |
| Abstract : Dong_2023_Ageing.Res.Rev_87_101910 |
| ESTHER : Dong_2023_Ageing.Res.Rev_87_101910 |
| PubMedSearch : Dong_2023_Ageing.Res.Rev_87_101910 |
| PubMedID: 36924572 |
| Title : Kaempferol, a potential neuroprotective agent in neurodegenerative diseases: From chemistry to medicine - Jin_2023_Biomed.Pharmacother_165_115215 |
| Author(s) : Jin S , Zhang L , Wang L |
| Ref : Biomed Pharmacother , 165 :115215 , 2023 |
| Abstract : Jin_2023_Biomed.Pharmacother_165_115215 |
| ESTHER : Jin_2023_Biomed.Pharmacother_165_115215 |
| PubMedSearch : Jin_2023_Biomed.Pharmacother_165_115215 |
| PubMedID: 37494786 |
| Title : Kaempferol counteracts toxicity induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in D. melanogaster: An implication of its mitoprotective activity - Adedara_2022_Neurotoxicol__ |
| Author(s) : Adedara AO , Wildner G , Loreto JS , Dos Santos MM , Abolaji AO , Barbosa NV |
| Ref : Neurotoxicology , : , 2022 |
| Abstract : Adedara_2022_Neurotoxicol__ |
| ESTHER : Adedara_2022_Neurotoxicol__ |
| PubMedSearch : Adedara_2022_Neurotoxicol__ |
| PubMedID: 36592898 |
| Title : Possible Role of Kaempferol in Reversing Oxidative Damage, Inflammation, and Apoptosis-Mediated Cortical Injury Following Cadmium Exposure - Al-Brakati_2021_Neurotox.Res_39_198 |
| Author(s) : Al-Brakati A , Albarakati AJA , Lokman MS , Theyab A , Algahtani M , Menshawi S , AlAmri OD , Al Omairi NE , Essawy EA , Kassab RB , Abdel Moneim AE |
| Ref : Neurotox Res , 39 :198 , 2021 |
| Abstract : Al-Brakati_2021_Neurotox.Res_39_198 |
| ESTHER : Al-Brakati_2021_Neurotox.Res_39_198 |
| PubMedSearch : Al-Brakati_2021_Neurotox.Res_39_198 |
| PubMedID: 33141427 |
| Title : A kaempferol derivative isolated from Lysimachia ramosa (Wall ex. Duby) induced alteration of acetylcholinesterase and nitric oxide synthase in Raillietina echinobothrida - Dey_2021_Vet.Parasitol_296_109461 |
| Author(s) : Dey P , Roy B , Mohanta R |
| Ref : Vet Parasitol , 296 :109461 , 2021 |
| Abstract : Dey_2021_Vet.Parasitol_296_109461 |
| ESTHER : Dey_2021_Vet.Parasitol_296_109461 |
| PubMedSearch : Dey_2021_Vet.Parasitol_296_109461 |
| PubMedID: 34214945 |
| Title : Enzymatic Hydrolysis of Kaempferol 3-O-(2'''-O-sinapoyl-beta-sophoroside), the Key Bitter Compound of Rapeseed (Brassica napus L.) Protein Isolate - Siebert_2021_J.Sci.Food.Agric__ |
| Author(s) : Siebert M , Krings U , Gunther T , Fragalas A , Berger RG |
| Ref : J Sci Food Agric , : , 2021 |
| Abstract : Siebert_2021_J.Sci.Food.Agric__ |
| ESTHER : Siebert_2021_J.Sci.Food.Agric__ |
| PubMedSearch : Siebert_2021_J.Sci.Food.Agric__ |
| PubMedID: 34580868 |
| Title : Inhibition of CpLIP2 Lipase Hydrolytic Activity by Four Flavonols (Galangin, Kaempferol, Quercetin, Myricetin) Compared to Orlistat and Their Binding Mechanisms Studied by Quenching of Fluorescence - Nasri_2019_Molecules_24_ |
| Author(s) : Nasri R , Bidel LPR , Rugani N , Perrier V , Carriere F , Dubreucq E , Jay-Allemand C |
| Ref : Molecules , 24 : , 2019 |
| Abstract : Nasri_2019_Molecules_24_ |
| ESTHER : Nasri_2019_Molecules_24_ |
| PubMedSearch : Nasri_2019_Molecules_24_ |
| PubMedID: 31398944 |
| Gene_locus related to this paper: canpa-LIP2 |
| Title : Anti-obesity effects of kaempferol by inhibiting adipogenesis and increasing lipolysis in 3T3-L1 cells - Torres-Villarreal_2019_J.Physiol.Biochem_75_83 |
| Author(s) : Torres-Villarreal D , Camacho A , Castro H , Ortiz-Lopez R , de la Garza AL |
| Ref : Journal de Physiologie Biochem , 75 :83 , 2019 |
| Abstract : Torres-Villarreal_2019_J.Physiol.Biochem_75_83 |
| ESTHER : Torres-Villarreal_2019_J.Physiol.Biochem_75_83 |
| PubMedSearch : Torres-Villarreal_2019_J.Physiol.Biochem_75_83 |
| PubMedID: 30539499 |
| Title : Phytochemical and Biological Profile of Moricandia arvensis (L.) DC.: An Inhibitor of Pancreatic Lipase - Marrelli_2018_Molecules_23_ |
| Author(s) : Marrelli M , Morrone F , Argentieri MP , Gambacorta L , Conforti F , Avato P |
| Ref : Molecules , 23 : , 2018 |
| Abstract : Marrelli_2018_Molecules_23_ |
| ESTHER : Marrelli_2018_Molecules_23_ |
| PubMedSearch : Marrelli_2018_Molecules_23_ |
| PubMedID: 30384448 |
| Title : Protective Effect of Kaempferol on the Transgenic Drosophila Model of Alzheimer's Disease - Beg_2018_CNS.Neurol.Disord.Drug.Targets_17_421 |
| Author(s) : Beg T , Jyoti S , Naz F , Rahul , Ali F , Ali SK , Reyad AM , Siddique YH |
| Ref : CNS Neurol Disord Drug Targets , 17 :421 , 2018 |
| Abstract : Beg_2018_CNS.Neurol.Disord.Drug.Targets_17_421 |
| ESTHER : Beg_2018_CNS.Neurol.Disord.Drug.Targets_17_421 |
| PubMedSearch : Beg_2018_CNS.Neurol.Disord.Drug.Targets_17_421 |
| PubMedID: 29745345 |
| Title : A neuroprotective role of kaempferol against chlorpyrifos-induced oxidative stress and memory deficits in rats via GSK3beta-Nrf2 signaling pathway - Hussein_2018_Pestic.Biochem.Physiol_152_29 |
| Author(s) : Hussein RM , Mohamed WR , Omar HA |
| Ref : Pestic Biochem Physiol , 152 :29 , 2018 |
| Abstract : Hussein_2018_Pestic.Biochem.Physiol_152_29 |
| ESTHER : Hussein_2018_Pestic.Biochem.Physiol_152_29 |
| PubMedSearch : Hussein_2018_Pestic.Biochem.Physiol_152_29 |
| PubMedID: 30497708 |