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Inhibitor Report for: Z-Pro-Prolinal-IC1

General
Type Benzyloxycarbonyl, Pyrrolidine, Peptide, tert-Butyl
Chemical_Nomenclature 1-[(2R,5S)-2-tert-butyl-5-[(2S)-2-[(1R)-1,2-dihydroxyethyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-4-phenylbutan-1-one
Canonical SMILES CC(C)(C)C1CCC(N1C(=O)CCCC2=CC=CC=C2)C(=O)N3CCCC3C(CO)O
InChI InChI=1S/C25H38N2O4/c1-25(2,3)22-15-14-20(24(31)26-16-8-12-19(26)21(29)17-28)27(22)23(30)13-7-11-18-9-5-4-6-10-18/h4-6,9-10,19-22,28-29H,7-8,11-17H2,1-3H3/t19-,20-,21-,22+/m0/s1
InChIKey JCVMLVYNFGCSKG-MYGLTJDJSA-N
Other name(s) IC1
________________________________________________________________________________________________
MW|430.58
Formula|C25H38N2O4
CAS_number|
PubChem|72200810
UniChem|JCVMLVYNFGCSKG-MYGLTJDJSA-N
IUPHAR|
Wikipedia|

Target
Families | Z-Pro-Prolinal-IC1 ligand of proteins in family: S9N_PPCE_Peptidase_S9
Stucture | 1 structure: 4AMY: Prolyl Oligopeptidase from porcine brain with a covalently bound inhibitor IC-1
Protein | pig-ppce

References:
Search PubMed for references concerning: Z-Pro-Prolinal-IC1
    Title: Molecular dynamics, crystallography and mutagenesis studies on the substrate gating mechanism of prolyl oligopeptidase.
    Kaszuba K, Rog T, Danne R, Canning P, Fulop V, Juhasz T, Szeltner Z, St Pierre JF, Garcia-Horsman A and Bunker A <3 more author(s)>
    Ref: Biochimie, 94:1398, 2012 : PubMed