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Kinetic Parameter
Orlistat_WT_human-PNLIP
Orlistat_WT_human-PNLIP
General
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human-BCHE
D70G
9000 uM
33200 /min
Lockridge_1990_Pharmacol.Ther_47_35
References (1)
1. Analysis of the discriminative inhibition of mammalian digestive lipases by 3-phenyl substituted 1,3,4-oxadiazol-2(3H)-ones. - Point_2012_Eur.J.Med.Chem_58_452
Title :
Analysis of the discriminative inhibition of mammalian digestive lipases by 3-phenyl substituted 1,3,4-oxadiazol-2(3H)-ones. -
Point_2012_Eur.J.Med.Chem_58_452
Author(s) :
Point V
,
Pavan Kumar KV
,
Marc S
,
Delorme V
,
Parsiegla G
,
Amara S
,
Carriere F
,
Buono G
,
Fotiadu F
,
Canaan S
,
Leclaire J
,
Cavalier JF
Ref :
Eur Journal of Medicinal Chemistry ,
58
:452 , 2012
Abstract :
View Abstract
PubMedSearch :
Point_2012_Eur.J.Med.Chem_58_452
PubMedID
:
23153815
Gene_locus related to this paper:
canfa-1lipg
,
cavpo-2plrp
,
human-CEL
,
human-PNLIP
,
human-PNLIPRP2
,
pig-1plip