E84C_mouse-ACHE

General

Gene Locus : mouse-ACHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Omega loop Omega loop conformation test incorporation of the fluorophore acrylodan Shi_2001_J.Biol.Chem_276_42196

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Omega loop conformation test || Omega loop

Torpedo_number : 82

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
p.Glu84Cys

References (3)

Title : Nanosecond dynamics of the mouse acetylcholinesterase cys69-cys96 omega loop - Shi_2003_J.Biol.Chem_278_30905
Author(s) : Shi J , Tai K , McCammon JA , Taylor P , Johnson DA
Ref : Journal of Biological Chemistry , 278 :30905 , 2003
PubMedID: 12759360

Title : Inhibitors of different structure induce distinguishing conformations in the omega loop, Cys 69- Cys 96, of mouse acetylcholinesterase - Shi_2002_J.Biol.Chem_277_43301
Author(s) : Shi J , Radic Z , Taylor P
Ref : Journal of Biological Chemistry , 277 :43301 , 2002
PubMedID: 12196517

Title : Reversibly bound and covalently attached ligands induce conformational changes in the Omega loop, Cys 69-Cys 96, of mouse acetylcholinesterase - Shi_2001_J.Biol.Chem_276_42196
Author(s) : Shi J , Boyd AE , Radic Z , Taylor P
Ref : Journal of Biological Chemistry , 276 :42196 , 2001
PubMedID: 11517229