N83Q_human-BCHE

General

Gene Locus : human-BCHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Substrate activation loss of substrate activation Masson_2001_Biochim.Biophys.Acta_1544_166

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Omega loop || Substrate activation

Torpedo_number : 85

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
p.N83Q Asn83Gln (p.N111Q Asn111Gln in primary sequence with 28 amino-acids signal peptide) loss of substrate activation

References (1)

Title : Effects of mutations of active site residues and amino acids interacting with the Omega loop on substrate activation of butyrylcholinesterase - Masson_2001_Biochim.Biophys.Acta_1544_166
Author(s) : Masson P , Xie W , Froment MT , Lockridge O
Ref : Biochimica & Biophysica Acta , 1544 :166 , 2001
Abstract :
PubMedSearch : Masson_2001_Biochim.Biophys.Acta_1544_166
PubMedID: 11341926
Gene_locus related to this paper: human-BCHE