Report for Lockridge O

General

Full name : Lockridge Oksana

First name : Oksana

Mail : University of Nebraska Medical Center, Eppley Institute, 985950 Nebraska Medical Center, Omaha, NE 68198-5950

Zip Code : 68198-6805

City : Omaha

Country : USA

Email : olockrid@unmc.edu

Phone : 402 559-6032

Fax : 402 559-4651

Website : \/\/www.unmc.edu\/eppley\/about\/faculty\/lockridge.html

Directory :

References (294)

Title : Overview of Adductomics in Toxicology - Lockridge_2023_Curr.Protoc_3_e672
Author(s) : Lockridge O
Ref : Curr Protoc , 3 :e672 , 2023
Abstract : Lockridge_2023_Curr.Protoc_3_e672
ESTHER : Lockridge_2023_Curr.Protoc_3_e672
PubMedSearch : Lockridge_2023_Curr.Protoc_3_e672
PubMedID: 36799690

Title : Human butyrylcholinesterase in Cohn fraction IV-4 purified in a single chromatography step on Hupresin - Schopfer_2023_PLoS.One_18_e0280380
Author(s) : Schopfer LM , David E , Hinrichs SH , Lockridge O
Ref : PLoS ONE , 18 :e0280380 , 2023
Abstract : Schopfer_2023_PLoS.One_18_e0280380
ESTHER : Schopfer_2023_PLoS.One_18_e0280380
PubMedSearch : Schopfer_2023_PLoS.One_18_e0280380
PubMedID: 36638134

Title : Drug and pro-drug substrates and pseudo-substrates of human butyrylcholinesterase - Masson_2023_Biochem.Pharmacol_218_115910
Author(s) : Masson P , Shaihutdinova Z , Lockridge O
Ref : Biochemical Pharmacology , 218 :115910 , 2023
Abstract : Masson_2023_Biochem.Pharmacol_218_115910
ESTHER : Masson_2023_Biochem.Pharmacol_218_115910
PubMedSearch : Masson_2023_Biochem.Pharmacol_218_115910
PubMedID: 37972875

Title : Review: Organophosphorus toxicants, in addition to inhibiting acetylcholinesterase activity, make covalent adducts on multiple proteins and promote protein crosslinking into high molecular weight aggregates - Lockridge_2023_Chem.Biol.Interact_14ChEPon_110460
Author(s) : Lockridge O , Schopfer LM
Ref : Chemico-Biological Interactions , :110460 , 2023
Abstract : Lockridge_2023_Chem.Biol.Interact_14ChEPon_110460
ESTHER : Lockridge_2023_Chem.Biol.Interact_14ChEPon_110460
PubMedSearch : Lockridge_2023_Chem.Biol.Interact_14ChEPon_110460
PubMedID: 36963650

Title : Butyrylcholinesterase in SH-SY5Y human neuroblastoma cells - Onder_2022_Neurotoxicol__
Author(s) : Onder S , Schopfer LM , Jiang W , Tacal O , Lockridge O
Ref : Neurotoxicology , : , 2022
Abstract : Onder_2022_Neurotoxicol__
ESTHER : Onder_2022_Neurotoxicol__
PubMedSearch : Onder_2022_Neurotoxicol__
PubMedID: 35189179

Title : Organophosphorus Pesticides Promote Protein Cross-Linking - Schopfer_2022_Chem.Res.Toxicol__
Author(s) : Schopfer LM , Onder S , Lockridge O
Ref : Chemical Research in Toxicology , : , 2022
Abstract : Schopfer_2022_Chem.Res.Toxicol__
ESTHER : Schopfer_2022_Chem.Res.Toxicol__
PubMedSearch : Schopfer_2022_Chem.Res.Toxicol__
PubMedID: 36048166

Title : Evaluation of mass spectrometry MS\/MS spectra for the presence of isopeptide crosslinked peptides - Schopfer_2021_PLoS.One_16_e0254450
Author(s) : Schopfer LM , Onder S , Lockridge O
Ref : PLoS ONE , 16 :e0254450 , 2021
Abstract : Schopfer_2021_PLoS.One_16_e0254450
ESTHER : Schopfer_2021_PLoS.One_16_e0254450
PubMedSearch : Schopfer_2021_PLoS.One_16_e0254450
PubMedID: 34242352

Title : Rabbit Antidiethoxyphosphotyrosine Antibody, Made by Single B Cell Cloning, Detects Chlorpyrifos Oxon-Modified Proteins in Cultured Cells and Immunopurifies Modified Peptides for Mass Spectrometry - Onder_2021_J.Proteome.Res__
Author(s) : Onder S , van Grol M , Fidder A , Xiao G , Noort D , Yerramalla U , Tacal O , Schopfer LM , Lockridge O
Ref : J Proteome Res , : , 2021
Abstract : Onder_2021_J.Proteome.Res__
ESTHER : Onder_2021_J.Proteome.Res__
PubMedSearch : Onder_2021_J.Proteome.Res__
PubMedID: 34469172

Title : Proline 285 is integral for the reactivation of organophosphate-inhibited human butyrylcholinesterase by 2-PAM - diTargiani_2020_Chem.Biol.Interact__109092
Author(s) : diTargiani RC , Belinskaya T , Tipparaju P , Lockridge O , Saxena A
Ref : Chemico-Biological Interactions , :109092 , 2020
Abstract : diTargiani_2020_Chem.Biol.Interact__109092
ESTHER : diTargiani_2020_Chem.Biol.Interact__109092
PubMedSearch : diTargiani_2020_Chem.Biol.Interact__109092
PubMedID: 32278739

Title : Characteristic fragment ions associated with dansyl cadaverine and biotin cadaverine adducts on glutamine - Biberoglu_2020_Anal.Biochem__113718
Author(s) : Biberoglu K , Schopfer LM , Tacal O , Lockridge O
Ref : Analytical Biochemistry , :113718 , 2020
Abstract : Biberoglu_2020_Anal.Biochem__113718
ESTHER : Biberoglu_2020_Anal.Biochem__113718
PubMedSearch : Biberoglu_2020_Anal.Biochem__113718
PubMedID: 32335065

Title : Polyproline-rich peptides associated with Torpedo californica acetylcholinesterase tetramers - Toker_2020_Chem.Biol.Interact__109007
Author(s) : Toker L , Silman I , Zeev-Ben-Mordehai T , Sussman JL , Schopfer LM , Lockridge O
Ref : Chemico-Biological Interactions , :109007 , 2020
Abstract : Toker_2020_Chem.Biol.Interact__109007
ESTHER : Toker_2020_Chem.Biol.Interact__109007
PubMedSearch : Toker_2020_Chem.Biol.Interact__109007
PubMedID: 32087110

Title : Signature Ions in MS\/MS Spectra for Dansyl-Aminohexyl-QQIV Adducts on Lysine - Schopfer_2020_Molecules_25_
Author(s) : Schopfer LM , Lockridge O
Ref : Molecules , 25 : , 2020
Abstract : Schopfer_2020_Molecules_25_
ESTHER : Schopfer_2020_Molecules_25_
PubMedSearch : Schopfer_2020_Molecules_25_
PubMedID: 32521655

Title : Chlorpyrifos Oxon-Induced Isopeptide Bond Formation in Human Butyrylcholinesterase - Biberoglu_2020_Molecules_25_
Author(s) : Biberoglu K , Tacal O , Schopfer LM , Lockridge O
Ref : Molecules , 25 : , 2020
Abstract : Biberoglu_2020_Molecules_25_
ESTHER : Biberoglu_2020_Molecules_25_
PubMedSearch : Biberoglu_2020_Molecules_25_
PubMedID: 31991818

Title : Half-life of chlorpyrifos oxon and other organophosphorus esters in aqueous solution - Lockridge_2019_Chem.Biol.Interact__108788
Author(s) : Lockridge O , Verdier L , Schopfer LM
Ref : Chemico-Biological Interactions , :108788 , 2019
Abstract : Lockridge_2019_Chem.Biol.Interact__108788
ESTHER : Lockridge_2019_Chem.Biol.Interact__108788
PubMedSearch : Lockridge_2019_Chem.Biol.Interact__108788
PubMedID: 31401088

Title : Computer-designed active human butyrylcholinesterase double mutant with a new catalytic triad - Grigorenko_2019_Chem.Biol.Interact_13ChEPon_306_138
Author(s) : Grigorenko BL , Novichkova DA , Lushchekina SV , Zueva IV , Schopfer LM , Nemukhin AV , Varfolomeev SD , Lockridge O , Masson P
Ref : Chemico-Biological Interactions , 306 :138 , 2019
Abstract : Grigorenko_2019_Chem.Biol.Interact_13ChEPon_306_138
ESTHER : Grigorenko_2019_Chem.Biol.Interact_13ChEPon_306_138
PubMedSearch : Grigorenko_2019_Chem.Biol.Interact_13ChEPon_306_138
PubMedID: 31009643

Title : Mass Spectrometry Identifies Isopeptide Cross-Links Promoted by Diethylphosphorylated Lysine in Proteins Treated with Chlorpyrifos Oxon - Schopfer_2019_Chem.Res.Toxicol_32_762
Author(s) : Schopfer LM , Lockridge O
Ref : Chemical Research in Toxicology , 32 :762 , 2019
Abstract : Schopfer_2019_Chem.Res.Toxicol_32_762
ESTHER : Schopfer_2019_Chem.Res.Toxicol_32_762
PubMedSearch : Schopfer_2019_Chem.Res.Toxicol_32_762
PubMedID: 30844252

Title : Purification of human butyrylcholinesterase from frozen Cohn fraction IV-4 by ion exchange and Hupresin affinity chromatography - Schopfer_2019_PLoS.One_14_e0209795
Author(s) : Schopfer LM , Lockridge O , David E , Hinrichs SH
Ref : PLoS ONE , 14 :e0209795 , 2019
Abstract : Schopfer_2019_PLoS.One_14_e0209795
ESTHER : Schopfer_2019_PLoS.One_14_e0209795
PubMedSearch : Schopfer_2019_PLoS.One_14_e0209795
PubMedID: 30625168

Title : Use of Hupresin To Capture Red Blood Cell Acetylcholinesterase for Detection of Soman Exposure - Onder_2018_Anal.Chem_90_974
Author(s) : Onder S , Schopfer LM , Cashman JR , Tacal O , Johnson RC , Blake TA , Lockridge O
Ref : Analytical Chemistry , 90 :974 , 2018
Abstract : Onder_2018_Anal.Chem_90_974
ESTHER : Onder_2018_Anal.Chem_90_974
PubMedSearch : Onder_2018_Anal.Chem_90_974
PubMedID: 29172437

Title : Characterization of butyrylcholinesterase from porcine milk - Saxena_2018_Arch.Biochem.Biophys_652_38
Author(s) : Saxena A , Belinskaya T , Schopfer LM , Lockridge O
Ref : Archives of Biochemistry & Biophysics , 652 :38 , 2018
Abstract : Saxena_2018_Arch.Biochem.Biophys_652_38
ESTHER : Saxena_2018_Arch.Biochem.Biophys_652_38
PubMedSearch : Saxena_2018_Arch.Biochem.Biophys_652_38
PubMedID: 29908755
Gene_locus related to this paper: pig-BCHE

Title : Cryo-EM structure of the native butyrylcholinesterase tetramer reveals a dimer of dimers stabilized by a superhelical assembly - Leung_2018_Proc.Natl.Acad.Sci.U.S.A_115_13270
Author(s) : Leung MR , van Bezouwen LS , Schopfer LM , Sussman JL , Silman I , Lockridge O , Zeev-Ben-Mordehai T
Ref : Proc Natl Acad Sci U S A , 115 :13270 , 2018
Abstract : Leung_2018_Proc.Natl.Acad.Sci.U.S.A_115_13270
ESTHER : Leung_2018_Proc.Natl.Acad.Sci.U.S.A_115_13270
PubMedSearch : Leung_2018_Proc.Natl.Acad.Sci.U.S.A_115_13270
PubMedID: 30538207
Gene_locus related to this paper: human-BCHE

Title : Delipidation of Plasma Has Minimal Effects on Human Butyrylcholinesterase - Onder_2018_Front.Pharmacol_9_117
Author(s) : Onder S , Tacal O , Lockridge O
Ref : Front Pharmacol , 9 :117 , 2018
Abstract : Onder_2018_Front.Pharmacol_9_117
ESTHER : Onder_2018_Front.Pharmacol_9_117
PubMedSearch : Onder_2018_Front.Pharmacol_9_117
PubMedID: 29497381

Title : Tetramer organizing polyproline-rich peptides identified by mass spectrometry after release of the peptides from Hupresin-purified butyrylcholinesterase tetramers isolated from milk of domestic pig (Sus scrofa) - Saxena_2018_Data.Brief_20_1607
Author(s) : Saxena A , Belinskaya T , Schopfer LM , Lockridge O
Ref : Data Brief , 20 :1607 , 2018
Abstract : Saxena_2018_Data.Brief_20_1607
ESTHER : Saxena_2018_Data.Brief_20_1607
PubMedSearch : Saxena_2018_Data.Brief_20_1607
PubMedID: 30263913

Title : Purification of recombinant human butyrylcholinesterase on Hupresin(R) - Lockridge_2018_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1102-1103_109
Author(s) : Lockridge O , David E , Schopfer LM , Masson P , Brazzolotto X , Nachon F
Ref : Journal of Chromatography B Analyt Technol Biomed Life Sciences , 1102-1103 :109 , 2018
Abstract : Lockridge_2018_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1102-1103_109
ESTHER : Lockridge_2018_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1102-1103_109
PubMedSearch : Lockridge_2018_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1102-1103_109
PubMedID: 30384187

Title : Identification of Carboxylesterase, Butyrylcholinesterase, Acetylcholinesterase, Paraoxonase, and Albumin Pseudoesterase in Guinea Pig Plasma through Nondenaturing Gel Electrophoresis - Napon_2018_Comp.Med_68_367
Author(s) : Napon G , Dafferner AJ , Saxena A , Lockridge O
Ref : Comp Med , 68 :367 , 2018
Abstract : Napon_2018_Comp.Med_68_367
ESTHER : Napon_2018_Comp.Med_68_367
PubMedSearch : Napon_2018_Comp.Med_68_367
PubMedID: 30278860

Title : Optimization of Cholinesterase-Based Catalytic Bioscavengers Against Organophosphorus Agents - Lushchekina_2018_Front.Pharmacol_9_211
Author(s) : Lushchekina SV , Schopfer LM , Grigorenko BL , Nemukhin AV , Varfolomeev SD , Lockridge O , Masson P
Ref : Front Pharmacol , 9 :211 , 2018
Abstract : Lushchekina_2018_Front.Pharmacol_9_211
ESTHER : Lushchekina_2018_Front.Pharmacol_9_211
PubMedSearch : Lushchekina_2018_Front.Pharmacol_9_211
PubMedID: 29593539

Title : Chlorpyrifos oxon promotes tubulin aggregation via isopeptide cross-linking between diethoxyphospho-Lys and Glu or Asp: Implications for neurotoxicity - Schopfer_2018_J.Biol.Chem_293_13566
Author(s) : Schopfer LM , Lockridge O
Ref : Journal of Biological Chemistry , 293 :13566 , 2018
Abstract : Schopfer_2018_J.Biol.Chem_293_13566
ESTHER : Schopfer_2018_J.Biol.Chem_293_13566
PubMedSearch : Schopfer_2018_J.Biol.Chem_293_13566
PubMedID: 30006344

Title : The C5 Variant of the Butyrylcholinesterase Tetramer Includes a Noncovalently Bound 60 kDa Lamellipodin Fragment - Schopfer_2017_Molecules_22_
Author(s) : Schopfer LM , Delacour H , Masson P , Leroy J , Krejci E , Lockridge O
Ref : Molecules , 22 : , 2017
Abstract : Schopfer_2017_Molecules_22_
ESTHER : Schopfer_2017_Molecules_22_
PubMedSearch : Schopfer_2017_Molecules_22_
PubMedID: 28661448
Gene_locus related to this paper: human-BCHE

Title : Immunopurification of Acetylcholinesterase from Red Blood Cells for Detection of Nerve Agent Exposure - Dafferner_2017_Chem.Res.Toxicol_30_1897
Author(s) : Dafferner AJ , Schopfer LM , Xiao G , Cashman JR , Yerramalla U , Johnson RC , Blake TA , Lockridge O
Ref : Chemical Research in Toxicology , 30 :1897 , 2017
Abstract : Dafferner_2017_Chem.Res.Toxicol_30_1897
ESTHER : Dafferner_2017_Chem.Res.Toxicol_30_1897
PubMedSearch : Dafferner_2017_Chem.Res.Toxicol_30_1897
PubMedID: 28892361

Title : Hupresin Retains Binding Capacity for Butyrylcholinesterase and Acetylcholinesterase after Sanitation with Sodium Hydroxide - Onder_2017_Front.Pharmacol_8_713
Author(s) : Onder S , David E , Tacal O , Schopfer LM , Lockridge O
Ref : Front Pharmacol , 8 :713 , 2017
Abstract : Onder_2017_Front.Pharmacol_8_713
ESTHER : Onder_2017_Front.Pharmacol_8_713
PubMedSearch : Onder_2017_Front.Pharmacol_8_713
PubMedID: 29066970

Title : Characterization of butyrylcholinesterase in bovine serum - Dafferner_2017_Chem.Biol.Interact_266_17
Author(s) : Dafferner AJ , Lushchekina SV , Masson P , Xiao G , Schopfer LM , Lockridge O
Ref : Chemico-Biological Interactions , 266 :17 , 2017
Abstract : Dafferner_2017_Chem.Biol.Interact_266_17
ESTHER : Dafferner_2017_Chem.Biol.Interact_266_17
PubMedSearch : Dafferner_2017_Chem.Biol.Interact_266_17
PubMedID: 28189703
Gene_locus related to this paper: bovin-BCHE

Title : Monoclonal Antibody That Recognizes Diethoxyphosphotyrosine-Modified Proteins and Peptides Independent of Surrounding Amino Acids - Onder_2017_Chem.Res.Toxicol_30_2218
Author(s) : Onder S , Dafferner AJ , Schopfer LM , Xiao G , Yerramalla U , Tacal O , Blake TA , Johnson RC , Lockridge O
Ref : Chemical Research in Toxicology , 30 :2218 , 2017
Abstract : Onder_2017_Chem.Res.Toxicol_30_2218
ESTHER : Onder_2017_Chem.Res.Toxicol_30_2218
PubMedSearch : Onder_2017_Chem.Res.Toxicol_30_2218
PubMedID: 29137457

Title : Heat pretreatment eliminates spurious butyrylcholinesterase enhancement of endotoxin levels in the kinetic chromogenic assay - Brawner_2016_Chem.Biol.Interact_249_19
Author(s) : Brawner A , Hinrichs SH , Larson MA , Lockridge O
Ref : Chemico-Biological Interactions , 249 :19 , 2016
Abstract : Brawner_2016_Chem.Biol.Interact_249_19
ESTHER : Brawner_2016_Chem.Biol.Interact_249_19
PubMedSearch : Brawner_2016_Chem.Biol.Interact_249_19
PubMedID: 26915974

Title : Naturally Occurring Genetic Variants of Human Acetylcholinesterase and Butyrylcholinesterase and Their Potential Impact on the Risk of Toxicity from Cholinesterase Inhibitors - Lockridge_2016_Chem.Res.Toxicol_29_1381
Author(s) : Lockridge O , Norgren RB, Jr. , Johnson RC , Blake TA
Ref : Chemical Research in Toxicology , 29 :1381 , 2016
Abstract : Lockridge_2016_Chem.Res.Toxicol_29_1381
ESTHER : Lockridge_2016_Chem.Res.Toxicol_29_1381
PubMedSearch : Lockridge_2016_Chem.Res.Toxicol_29_1381
PubMedID: 27551784

Title : Monoclonal Antibodies That Recognize Various Folding States of Pure Human Butyrylcholinesterase Can Immunopurify Butyrylcholinesterase from Human Plasma Stored at Elevated Temperatures - Peng_2016_ACS.Omega_1_1182
Author(s) : Peng H , Blake TA , Johnson RC , Dafferner AJ , Brimijoin S , Lockridge O
Ref : ACS Omega , 1 :1182 , 2016
Abstract : Peng_2016_ACS.Omega_1_1182
ESTHER : Peng_2016_ACS.Omega_1_1182
PubMedSearch : Peng_2016_ACS.Omega_1_1182
PubMedID: 28058292

Title : Tetramer-organizing polyproline-rich peptides differ in CHO cell-expressed and plasma-derived human butyrylcholinesterase tetramers - Schopfer_2016_Biochim.Biophys.Acta_1864_706
Author(s) : Schopfer LM , Lockridge O
Ref : Biochimica & Biophysica Acta , 1864 :706 , 2016
Abstract : Schopfer_2016_Biochim.Biophys.Acta_1864_706
ESTHER : Schopfer_2016_Biochim.Biophys.Acta_1864_706
PubMedSearch : Schopfer_2016_Biochim.Biophys.Acta_1864_706
PubMedID: 26947244

Title : Monoclonal antibodies to human butyrylcholinesterase reactive with butyrylcholinesterase in animal plasma - Peng_2016_Chem.Biol.Interact_243_82
Author(s) : Peng H , Brimijoin S , Hrabovska A , Krejci E , Blake TA , Johnson RC , Masson P , Lockridge O
Ref : Chemico-Biological Interactions , 243 :82 , 2016
Abstract : Peng_2016_Chem.Biol.Interact_243_82
ESTHER : Peng_2016_Chem.Biol.Interact_243_82
PubMedSearch : Peng_2016_Chem.Biol.Interact_243_82
PubMedID: 26585590

Title : Origin of polyproline-rich peptides in human butyrylcholinesterase tetramers - Peng_2016_Chem.Biol.Interact_259_63
Author(s) : Peng H , Schopfer LM , Lockridge O
Ref : Chemico-Biological Interactions , 259 :63 , 2016
Abstract : Peng_2016_Chem.Biol.Interact_259_63
ESTHER : Peng_2016_Chem.Biol.Interact_259_63
PubMedSearch : Peng_2016_Chem.Biol.Interact_259_63
PubMedID: 26876904

Title : Comparison of 5 monoclonal antibodies for immunopurification of human butyrylcholinesterase on Dynabeads: K values, binding pairs, and amino acid sequences - Peng_2015_Chem.Biol.Interact_240_336
Author(s) : Peng H , Brimijoin S , Hrabovska A , Targosova K , Krejci E , Blake TA , Johnson RC , Masson P , Lockridge O
Ref : Chemico-Biological Interactions , 240 :336 , 2015
Abstract : Peng_2015_Chem.Biol.Interact_240_336
ESTHER : Peng_2015_Chem.Biol.Interact_240_336
PubMedSearch : Peng_2015_Chem.Biol.Interact_240_336
PubMedID: 26343001

Title : Review of human butyrylcholinesterase structure, function, genetic variants, history of use in the clinic, and potential therapeutic uses - Lockridge_2015_Pharmacol.Ther_148C_34
Author(s) : Lockridge O
Ref : Pharmacol Ther , 148C :34 , 2015
Abstract : Lockridge_2015_Pharmacol.Ther_148C_34
ESTHER : Lockridge_2015_Pharmacol.Ther_148C_34
PubMedSearch : Lockridge_2015_Pharmacol.Ther_148C_34
PubMedID: 25448037

Title : Butyrylcholinesterase genotype and enzyme activity in relation to Gulf War illness: preliminary evidence of gene-exposure interaction from a case-control study of 1991 Gulf War veterans - Steele_2015_Environ.Health_14_4
Author(s) : Steele L , Lockridge O , Gerkovich MM , Cook MR , Sastre A
Ref : Environ Health , 14 :4 , 2015
Abstract : Steele_2015_Environ.Health_14_4
ESTHER : Steele_2015_Environ.Health_14_4
PubMedSearch : Steele_2015_Environ.Health_14_4
PubMedID: 25575675

Title : Human butyrylcholinesterase polymorphism: Molecular modeling - Lushchekina_2015_Int.J.Risk.Saf.Med_27 Suppl 1_S80
Author(s) : Lushchekina SV , Delacour H , Lockridge O , Masson P
Ref : Int J Risk Saf Med , 27 Suppl 1 :S80 , 2015
Abstract : Lushchekina_2015_Int.J.Risk.Saf.Med_27 Suppl 1_S80
ESTHER : Lushchekina_2015_Int.J.Risk.Saf.Med_27 Suppl 1_S80
PubMedSearch : Lushchekina_2015_Int.J.Risk.Saf.Med_27 Suppl 1_S80
PubMedID: 26639724

Title : Pure human butyrylcholinesterase hydrolyzes octanoyl ghrelin to desacyl ghrelin - Schopfer_2015_Gen.Comp.Endocrinol_224_61
Author(s) : Schopfer LM , Lockridge O , Brimijoin S
Ref : General & Comparative Endocrinology , 224 :61 , 2015
Abstract : Schopfer_2015_Gen.Comp.Endocrinol_224_61
ESTHER : Schopfer_2015_Gen.Comp.Endocrinol_224_61
PubMedSearch : Schopfer_2015_Gen.Comp.Endocrinol_224_61
PubMedID: 26073531

Title : Polyproline promotes tetramerization of recombinant human butyrylcholinesterase - Larson_2014_Biochem.J_462_329
Author(s) : Larson MA , Lockridge O , Hinrichs SH
Ref : Biochemical Journal , 462 :329 , 2014
Abstract : Larson_2014_Biochem.J_462_329
ESTHER : Larson_2014_Biochem.J_462_329
PubMedSearch : Larson_2014_Biochem.J_462_329
PubMedID: 24916051

Title : Characterization of a Novel BCHE Silent Allele: Point Mutation (p.Val204Asp) Causes Loss of Activity and Prolonged Apnea with Suxamethonium - Delacour_2014_PLoS.One_9_e101552
Author(s) : Delacour H , Lushchekina SV , Mabboux I , Bousquet A , Ceppa F , Schopfer LM , Lockridge O , Masson P
Ref : PLoS ONE , 9 :e101552 , 2014
Abstract : Delacour_2014_PLoS.One_9_e101552
ESTHER : Delacour_2014_PLoS.One_9_e101552
PubMedSearch : Delacour_2014_PLoS.One_9_e101552
PubMedID: 25054547

Title : Characterization of a novel butyrylcholinesterase point mutation (p.Ala34Val), silent with mivacurium - Delacour_2014_Biochem.Pharmacol_92_476
Author(s) : Delacour H , Lushchekina SV , Mabboux I , Ceppa F , Masson P , Schopfer LM , Lockridge O
Ref : Biochemical Pharmacology , 92 :476 , 2014
Abstract : Delacour_2014_Biochem.Pharmacol_92_476
ESTHER : Delacour_2014_Biochem.Pharmacol_92_476
PubMedSearch : Delacour_2014_Biochem.Pharmacol_92_476
PubMedID: 25264279

Title : Detection of cresyl phosphate-modified butyrylcholinesterase in human plasma for chemical exposure associated with aerotoxic syndrome - Schopfer_2014_Anal.Biochem_461C_17
Author(s) : Schopfer LM , Masson P , Lamourette P , Simon S , Lockridge O
Ref : Analytical Biochemistry , 461C :17 , 2014
Abstract : Schopfer_2014_Anal.Biochem_461C_17
ESTHER : Schopfer_2014_Anal.Biochem_461C_17
PubMedSearch : Schopfer_2014_Anal.Biochem_461C_17
PubMedID: 24892986

Title : Cresyl saligenin phosphate makes multiple adducts on free histidine, but does not form an adduct on histidine 438 of human butyrylcholinesterase - Liyasova_2013_Chem.Biol.Interact_203_103
Author(s) : Liyasova MS , Schopfer LM , Lockridge O
Ref : Chemico-Biological Interactions , 203 :103 , 2013
Abstract : Liyasova_2013_Chem.Biol.Interact_203_103
ESTHER : Liyasova_2013_Chem.Biol.Interact_203_103
PubMedSearch : Liyasova_2013_Chem.Biol.Interact_203_103
PubMedID: 22898212

Title : Effects of viscosity and osmotic stress on the reaction of human butyrylcholinesterase with cresyl saligenin phosphate, a toxicant related to aerotoxic syndrome: kinetic and molecular dynamics studies - Masson_2013_Biochem.J_454_387
Author(s) : Masson P , Lushchekina SV , Schopfer LM , Lockridge O
Ref : Biochemical Journal , 454 :387 , 2013
Abstract : Masson_2013_Biochem.J_454_387
ESTHER : Masson_2013_Biochem.J_454_387
PubMedSearch : Masson_2013_Biochem.J_454_387
PubMedID: 23782236

Title : Detectable organophosphorus pesticide exposure in the blood of Nebraska and Iowa residents measured by mass spectrometry of butyrylcholinesterase adducts - Jiang_2013_Chem.Biol.Interact_203_91
Author(s) : Jiang W , Lockridge O
Ref : Chemico-Biological Interactions , 203 :91 , 2013
Abstract : Jiang_2013_Chem.Biol.Interact_203_91
ESTHER : Jiang_2013_Chem.Biol.Interact_203_91
PubMedSearch : Jiang_2013_Chem.Biol.Interact_203_91
PubMedID: 22989774

Title : Resistance of human butyrylcholinesterase to methylene blue-catalyzed photoinactivation\; mass spectrometry analysis of oxidation products - Tacal_2013_Photochem.Photobiol_89_336
Author(s) : Tacal O , Li B , Lockridge O , Schopfer LM
Ref : Photochem Photobiol , 89 :336 , 2013
Abstract : Tacal_2013_Photochem.Photobiol_89_336
ESTHER : Tacal_2013_Photochem.Photobiol_89_336
PubMedSearch : Tacal_2013_Photochem.Photobiol_89_336
PubMedID: 23136924

Title : Mass spectrometry method to identify aging pathways of Sp- and Rp-tabun adducts on human butyrylcholinesterase based on the acid labile P-N bond - Jiang_2013_Toxicol.Sci_132_390
Author(s) : Jiang W , Cashman JR , Nachon F , Masson P , Schopfer LM , Lockridge O
Ref : Toxicol Sci , 132 :390 , 2013
Abstract : Jiang_2013_Toxicol.Sci_132_390
ESTHER : Jiang_2013_Toxicol.Sci_132_390
PubMedSearch : Jiang_2013_Toxicol.Sci_132_390
PubMedID: 23345579

Title : Newly observed spontaneous activation of ethephon as a butyrylcholinesterase inhibitor - Liyasova_2013_Chem.Res.Toxicol_26_422
Author(s) : Liyasova MS , Schopfer LM , Kodani S , Lantz SR , Casida JE , Lockridge O
Ref : Chemical Research in Toxicology , 26 :422 , 2013
Abstract : Liyasova_2013_Chem.Res.Toxicol_26_422
ESTHER : Liyasova_2013_Chem.Res.Toxicol_26_422
PubMedSearch : Liyasova_2013_Chem.Res.Toxicol_26_422
PubMedID: 23410221

Title : PHOS-Select Iron Affinity Beads Enrich Peptides for the Detection of Organophosphorus Adducts on Albumin - Jiang_2013_Chem.Res.Toxicol_26_1917
Author(s) : Jiang W , Dubrovskii YA , Podolskaya EP , Murashko EA , Babakov VN , Nachon F , Masson P , Schopfer LM , Lockridge O
Ref : Chemical Research in Toxicology , 26 :1917 , 2013
Abstract : Jiang_2013_Chem.Res.Toxicol_26_1917
ESTHER : Jiang_2013_Chem.Res.Toxicol_26_1917
PubMedSearch : Jiang_2013_Chem.Res.Toxicol_26_1917
PubMedID: 24187955

Title : Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry - Carletti_2013_Chem.Res.Toxicol_26_280
Author(s) : Carletti E , Colletier JP , Schopfer LM , Santoni G , Masson P , Lockridge O , Nachon F , Weik M
Ref : Chemical Research in Toxicology , 26 :280 , 2013
Abstract : Carletti_2013_Chem.Res.Toxicol_26_280
ESTHER : Carletti_2013_Chem.Res.Toxicol_26_280
PubMedSearch : Carletti_2013_Chem.Res.Toxicol_26_280
PubMedID: 23339663
Gene_locus related to this paper: human-BCHE , mouse-ACHE

Title : Application of chromosomal DNA and protein targeting for the identification of Yersinia pestis - Larson_2013_Proteomics.Clin.Appl_7_416
Author(s) : Larson MA , Ding SJ , Slater SR , Hanway A , Bartling AM , Fey PD , Lockridge O , Francesconi SC , Hinrichs SH
Ref : Proteomics Clin Appl , 7 :416 , 2013
Abstract : Larson_2013_Proteomics.Clin.Appl_7_416
ESTHER : Larson_2013_Proteomics.Clin.Appl_7_416
PubMedSearch : Larson_2013_Proteomics.Clin.Appl_7_416
PubMedID: 23436733

Title : Human serum albumin-based design of a diflunisal prodrug - Yang_2013_Eur.J.Pharm.Biopharm_84_549
Author(s) : Yang F , Ma ZY , Zhang Y , Li GQ , Li M , Qin JK , Lockridge O , Liang H
Ref : Eur J Pharm Biopharm , 84 :549 , 2013
Abstract : Yang_2013_Eur.J.Pharm.Biopharm_84_549
ESTHER : Yang_2013_Eur.J.Pharm.Biopharm_84_549
PubMedSearch : Yang_2013_Eur.J.Pharm.Biopharm_84_549
PubMedID: 23416065

Title : Matrix-assisted laser desorption\/ionization time-of-flight mass spectrometry of titanium oxide-enriched peptides for detection of aged organophosphorus adducts on human butyrylcholinesterase - Jiang_2013_Anal.Biochem_439_132
Author(s) : Jiang W , Murashko EA , Dubrovskii YA , Podolskaya EP , Babakov VN , Mikler J , Nachon F , Masson P , Schopfer LM , Lockridge O
Ref : Analytical Biochemistry , 439 :132 , 2013
Abstract : Jiang_2013_Anal.Biochem_439_132
ESTHER : Jiang_2013_Anal.Biochem_439_132
PubMedSearch : Jiang_2013_Anal.Biochem_439_132
PubMedID: 23624322

Title : Polyproline tetramer organizing peptides in fetal bovine serum acetylcholinesterase - Biberoglu_2013_Biochim.Biophys.Acta_1834_745
Author(s) : Biberoglu K , Schopfer LM , Saxena A , Tacal O , Lockridge O
Ref : Biochimica & Biophysica Acta , 1834 :745 , 2013
Abstract : Biberoglu_2013_Biochim.Biophys.Acta_1834_745
ESTHER : Biberoglu_2013_Biochim.Biophys.Acta_1834_745
PubMedSearch : Biberoglu_2013_Biochim.Biophys.Acta_1834_745
PubMedID: 23352838

Title : Polyclonal antibody to soman-tyrosine - Li_2013_Chem.Res.Toxicol_26_584
Author(s) : Li B , Duysen EG , Froment MT , Masson P , Nachon F , Jiang W , Schopfer LM , Thiele GM , Klassen LW , Cashman JR , Williams GR , Lockridge O
Ref : Chemical Research in Toxicology , 26 :584 , 2013
Abstract : Li_2013_Chem.Res.Toxicol_26_584
ESTHER : Li_2013_Chem.Res.Toxicol_26_584
PubMedSearch : Li_2013_Chem.Res.Toxicol_26_584
PubMedID: 23469927

Title : Human butyrylcholinesterase produced in insect cells: huprine-based affinity purification and crystal structure - Brazzolotto_2012_Febs.J_279_2905
Author(s) : Brazzolotto X , Wandhammer M , Ronco C , Trovaslet M , Jean L , Lockridge O , Renard PY , Nachon F
Ref : Febs J , 279 :2905 , 2012
Abstract : Brazzolotto_2012_Febs.J_279_2905
ESTHER : Brazzolotto_2012_Febs.J_279_2905
PubMedSearch : Brazzolotto_2012_Febs.J_279_2905
PubMedID: 22726956
Gene_locus related to this paper: human-BCHE

Title : Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis - Hlady_2012_J.Clin.Invest_122_163
Author(s) : Hlady RA , Novakova S , Opavska J , Klinkebiel D , Peters SL , Bies J , Hannah J , Iqbal J , Anderson KM , Siebler HM , Smith LM , Greiner TC , Bastola D , Joshi S , Lockridge O , Simpson MA , Felsher DW , Wagner KU , Chan WC , Christman JK , Opavsky R
Ref : J Clinical Investigation , 122 :163 , 2012
Abstract : Hlady_2012_J.Clin.Invest_122_163
ESTHER : Hlady_2012_J.Clin.Invest_122_163
PubMedSearch : Hlady_2012_J.Clin.Invest_122_163
PubMedID: 22133874

Title : Analytical approaches for monitoring exposure to organophosphorus and carbamate agents through analysis of protein adducts - Schopfer_2012_Drug.Test.Anal_4_246
Author(s) : Schopfer LM , Lockridge O
Ref : Drug Test Anal , 4 :246 , 2012
Abstract : Schopfer_2012_Drug.Test.Anal_4_246
ESTHER : Schopfer_2012_Drug.Test.Anal_4_246
PubMedSearch : Schopfer_2012_Drug.Test.Anal_4_246
PubMedID: 22359362

Title : Differential sensitivity of plasma carboxylesterase-null mice to parathion, chlorpyrifos and chlorpyrifos oxon, but not to diazinon, dichlorvos, diisopropylfluorophosphate, cresyl saligenin phosphate, cyclosarin thiocholine, tabun thiocholine, and carbofuran - Duysen_2012_Chem.Biol.Interact_195_189
Author(s) : Duysen EG , Cashman JR , Schopfer LM , Nachon F , Masson P , Lockridge O
Ref : Chemico-Biological Interactions , 195 :189 , 2012
Abstract : Duysen_2012_Chem.Biol.Interact_195_189
ESTHER : Duysen_2012_Chem.Biol.Interact_195_189
PubMedSearch : Duysen_2012_Chem.Biol.Interact_195_189
PubMedID: 22209767

Title : The proline-rich tetramerization peptides in equine serum butyrylcholinesterase - Biberoglu_2012_Febs.J_279_3844
Author(s) : Biberoglu K , Schopfer LM , Tacal O , Lockridge O
Ref : Febs J , 279 :3844 , 2012
Abstract : Biberoglu_2012_Febs.J_279_3844
ESTHER : Biberoglu_2012_Febs.J_279_3844
PubMedSearch : Biberoglu_2012_Febs.J_279_3844
PubMedID: 22889087

Title : Mice treated with a nontoxic dose of chlorpyrifos oxon have diethoxyphosphotyrosine labeled proteins in blood up to 4 days post exposure, detected by mass spectrometry - Jiang_2012_Toxicology_295_15
Author(s) : Jiang W , Duysen EG , Lockridge O
Ref : Toxicology , 295 :15 , 2012
Abstract : Jiang_2012_Toxicology_295_15
ESTHER : Jiang_2012_Toxicology_295_15
PubMedSearch : Jiang_2012_Toxicology_295_15
PubMedID: 22406659

Title : Cresyl saligenin phosphate, an organophosphorus toxicant, makes covalent adducts with histidine, lysine, and tyrosine residues of human serum albumin - Liyasova_2012_Chem.Res.Toxicol_25_1752
Author(s) : Liyasova MS , Schopfer LM , Lockridge O
Ref : Chemical Research in Toxicology , 25 :1752 , 2012
Abstract : Liyasova_2012_Chem.Res.Toxicol_25_1752
ESTHER : Liyasova_2012_Chem.Res.Toxicol_25_1752
PubMedSearch : Liyasova_2012_Chem.Res.Toxicol_25_1752
PubMedID: 22793878

Title : The kinetic study of the inhibition of human cholinesterases by demeton-S-methyl shows that cholinesterase-based titration methods are not suitable for this organophosphate - Bazire_2011_Toxicol.In.Vitro_25_754
Author(s) : Bazire A , Gillon E , Lockridge O , Vallet V , Nachon F
Ref : Toxicol In Vitro , 25 :754 , 2011
Abstract : Bazire_2011_Toxicol.In.Vitro_25_754
ESTHER : Bazire_2011_Toxicol.In.Vitro_25_754
PubMedSearch : Bazire_2011_Toxicol.In.Vitro_25_754
PubMedID: 21238577

Title : Gene-Delivered Butyrylcholinesterase Is Prophylactic against the Toxicity of Chemical Warfare Nerve Agents and Organophosphorus Compounds - Parikh_2011_J.Pharmacol.Exp.Ther_337_92
Author(s) : Parikh K , Duysen EG , Snow B , Jensen NS , Manne V , Lockridge O , Chilukuri N
Ref : Journal of Pharmacology & Experimental Therapeutics , 337 :92 , 2011
Abstract : Parikh_2011_J.Pharmacol.Exp.Ther_337_92
ESTHER : Parikh_2011_J.Pharmacol.Exp.Ther_337_92
PubMedSearch : Parikh_2011_J.Pharmacol.Exp.Ther_337_92
PubMedID: 21205915

Title : Induction of plasma acetylcholinesterase activity in mice challenged with organophosphorus poisons - Duysen_2011_Toxicol.Appl.Pharmacol_255_214
Author(s) : Duysen EG , Lockridge O
Ref : Toxicol Appl Pharmacol , 255 :214 , 2011
Abstract : Duysen_2011_Toxicol.Appl.Pharmacol_255_214
ESTHER : Duysen_2011_Toxicol.Appl.Pharmacol_255_214
PubMedSearch : Duysen_2011_Toxicol.Appl.Pharmacol_255_214
PubMedID: 21767560

Title : Biomarkers of organophosphorus (OP) exposures in humans - Marsillach_2011_Neurotoxicol_32_656
Author(s) : Marsillach J , Richter RJ , Kim JH , Stevens RC , Maccoss MJ , Tomazela D , Suzuki SM , Schopfer LM , Lockridge O , Furlong CE
Ref : Neurotoxicology , 32 :656 , 2011
Abstract : Marsillach_2011_Neurotoxicol_32_656
ESTHER : Marsillach_2011_Neurotoxicol_32_656
PubMedSearch : Marsillach_2011_Neurotoxicol_32_656
PubMedID: 21767566

Title : Adenovirus-mediated human paraoxonase1 gene transfer to provide protection against the toxicity of the organophosphorus pesticide toxicant diazoxon - Duysen_2011_Gene.Ther_18_250
Author(s) : Duysen EG , Parikh K , Aleti V , Manne V , Lockridge O , Chilukuri N
Ref : Gene Therapy , 18 :250 , 2011
Abstract : Duysen_2011_Gene.Ther_18_250
ESTHER : Duysen_2011_Gene.Ther_18_250
PubMedSearch : Duysen_2011_Gene.Ther_18_250
PubMedID: 20981111

Title : X-ray crystallographic snapshots of reaction intermediates in the G117H mutant of human butyrylcholinesterase, a nerve agent target engineered into a catalytic bioscavenger - Nachon_2011_Biochem.J_434_73
Author(s) : Nachon F , Carletti E , Wandhammer M , Nicolet Y , Schopfer LM , Masson P , Lockridge O
Ref : Biochemical Journal , 434 :73 , 2011
Abstract : Nachon_2011_Biochem.J_434_73
ESTHER : Nachon_2011_Biochem.J_434_73
PubMedSearch : Nachon_2011_Biochem.J_434_73
PubMedID: 21091433
Gene_locus related to this paper: human-BCHE

Title : Role of acetylcholinesterase on the structure and function of cholinergic synapses: insights gained from studies on knockout mice - Adler_2011_Cell.Mol.Neurobiol_31_909
Author(s) : Adler M , Sweeney RE , Hamilton TA , Lockridge O , Duysen EG , Purcell AL , Deshpande SS
Ref : Cellular Molecular Neurobiology , 31 :909 , 2011
Abstract : Adler_2011_Cell.Mol.Neurobiol_31_909
ESTHER : Adler_2011_Cell.Mol.Neurobiol_31_909
PubMedSearch : Adler_2011_Cell.Mol.Neurobiol_31_909
PubMedID: 21538119

Title : Reaction of cresyl saligenin phosphate, the organophosphorus agent implicated in aerotoxic syndrome, with human cholinesterases: mechanistic studies employing kinetics, mass spectrometry, and X-ray structure analysis - Carletti_2011_Chem.Res.Toxicol_24_797
Author(s) : Carletti E , Schopfer LM , Colletier JP , Froment MT , Nachon F , Weik M , Lockridge O , Masson P
Ref : Chemical Research in Toxicology , 24 :797 , 2011
Abstract : Carletti_2011_Chem.Res.Toxicol_24_797
ESTHER : Carletti_2011_Chem.Res.Toxicol_24_797
PubMedSearch : Carletti_2011_Chem.Res.Toxicol_24_797
PubMedID: 21438623
Gene_locus related to this paper: human-BCHE

Title : Exposure to tri-o-cresyl phosphate detected in jet airplane passengers - Liyasova_2011_Toxicol.Appl.Pharmacol_256_337
Author(s) : Liyasova M , Li B , Schopfer LM , Nachon F , Masson P , Furlong CE , Lockridge O
Ref : Toxicol Appl Pharmacol , 256 :337 , 2011
Abstract : Liyasova_2011_Toxicol.Appl.Pharmacol_256_337
ESTHER : Liyasova_2011_Toxicol.Appl.Pharmacol_256_337
PubMedSearch : Liyasova_2011_Toxicol.Appl.Pharmacol_256_337
PubMedID: 21723309

Title : Cocrystallization studies of full-length recombinant butyrylcholinesterase (BChE) with cocaine - Asojo_2011_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_67_434
Author(s) : Asojo OA , Ngamelue MN , Homma K , Lockridge O
Ref : Acta Crystallographica Sect F Struct Biol Cryst Commun , 67 :434 , 2011
Abstract : Asojo_2011_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_67_434
ESTHER : Asojo_2011_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_67_434
PubMedSearch : Asojo_2011_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_67_434
PubMedID: 21505234
Gene_locus related to this paper: human-BCHE

Title : Production of ES1 plasma carboxylesterase knockout mice for toxicity studies - Duysen_2011_Chem.Res.Toxicol_24_1891
Author(s) : Duysen EG , Koentgen F , Williams GR , Timperley CM , Schopfer LM , Cerasoli DM , Lockridge O
Ref : Chemical Research in Toxicology , 24 :1891 , 2011
Abstract : Duysen_2011_Chem.Res.Toxicol_24_1891
ESTHER : Duysen_2011_Chem.Res.Toxicol_24_1891
PubMedSearch : Duysen_2011_Chem.Res.Toxicol_24_1891
PubMedID: 21875074
Gene_locus related to this paper: mouse-Ces1c

Title : Transglutaminase-mediated remodeling of the human erythrocyte membrane skeleton: relevance for erythrocyte diseases with shortened cell lifespan -
Author(s) : Lorand L , Murthy SN , Khan AA , Xue W , Lockridge O , Chishti AH
Ref : Adv Enzymol Relat Areas Mol Biol , 78 :385 , 2011
PubMedID: 22220479

Title : Prolonged toxic effects after cocaine challenge in butyrylcholinesterase\/plasma carboxylesterase double knockout mice: a model for butyrylcholinesterase-deficient humans - Duysen_2011_Drug.Metab.Dispos_39_1321
Author(s) : Duysen EG , Lockridge O
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 39 :1321 , 2011
Abstract : Duysen_2011_Drug.Metab.Dispos_39_1321
ESTHER : Duysen_2011_Drug.Metab.Dispos_39_1321
PubMedSearch : Duysen_2011_Drug.Metab.Dispos_39_1321
PubMedID: 21540357

Title : Visualization of exogenous delivery of nanoformulated butyrylcholinesterase to the central nervous system - Gaydess_2010_Chem.Biol.Interact_187_295
Author(s) : Gaydess A , Duysen E , Li Y , Gilman V , Kabanov A , Lockridge O , Bronich T
Ref : Chemico-Biological Interactions , 187 :295 , 2010
Abstract : Gaydess_2010_Chem.Biol.Interact_187_295
ESTHER : Gaydess_2010_Chem.Biol.Interact_187_295
PubMedSearch : Gaydess_2010_Chem.Biol.Interact_187_295
PubMedID: 20060815

Title : Review of tyrosine and lysine as new motifs for organophosphate binding to proteins that have no active site serine - Lockridge_2010_Chem.Biol.Interact_187_344
Author(s) : Lockridge O , Schopfer LM
Ref : Chemico-Biological Interactions , 187 :344 , 2010
Abstract : Lockridge_2010_Chem.Biol.Interact_187_344
ESTHER : Lockridge_2010_Chem.Biol.Interact_187_344
PubMedSearch : Lockridge_2010_Chem.Biol.Interact_187_344
PubMedID: 20211158

Title : Mass spectral characterization of organophosphate-labeled, tyrosine-containing peptides: characteristic mass fragments and a new binding motif for organophosphates - Schopfer_2010_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_878_1297
Author(s) : Schopfer LM , Grigoryan H , Li B , Nachon F , Masson P , Lockridge O
Ref : Journal of Chromatography B Analyt Technol Biomed Life Sciences , 878 :1297 , 2010
Abstract : Schopfer_2010_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_878_1297
ESTHER : Schopfer_2010_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_878_1297
PubMedSearch : Schopfer_2010_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_878_1297
PubMedID: 19762289

Title : Mice treated with chlorpyrifos or chlorpyrifos oxon have organophosphorylated tubulin in the brain and disrupted microtubule structures, suggesting a role for tubulin in neurotoxicity associated with exposure to organophosphorus agents - Jiang_2010_Toxicol.Sci_115_183
Author(s) : Jiang W , Duysen EG , Hansen H , Shlyakhtenko L , Schopfer LM , Lockridge O
Ref : Toxicol Sci , 115 :183 , 2010
Abstract : Jiang_2010_Toxicol.Sci_115_183
ESTHER : Jiang_2010_Toxicol.Sci_115_183
PubMedSearch : Jiang_2010_Toxicol.Sci_115_183
PubMedID: 20142434

Title : Contributions of selective knockout studies to understanding cholinesterase disposition and function - Camp_2010_Chem.Biol.Interact_187_72
Author(s) : Camp S , Zhang L , Krejci E , Dobbertin A , Bernard V , Girard E , Duysen EG , Lockridge O , De Jaco A , Taylor P
Ref : Chemico-Biological Interactions , 187 :72 , 2010
Abstract : Camp_2010_Chem.Biol.Interact_187_72
ESTHER : Camp_2010_Chem.Biol.Interact_187_72
PubMedSearch : Camp_2010_Chem.Biol.Interact_187_72
PubMedID: 20153304

Title : Methamidophos, dichlorvos, O-methoate and diazinon pesticides used in Turkey make a covalent bond with butyrylcholinesterase detected by mass spectrometry - Tacal_2010_J.Appl.Toxicol_30_469
Author(s) : Tacal O , Lockridge O
Ref : J Appl Toxicol , 30 :469 , 2010
Abstract : Tacal_2010_J.Appl.Toxicol_30_469
ESTHER : Tacal_2010_J.Appl.Toxicol_30_469
PubMedSearch : Tacal_2010_J.Appl.Toxicol_30_469
PubMedID: 20229498

Title : Dichlorvos, chlorpyrifos oxon and Aldicarb adducts of butyrylcholinesterase, detected by mass spectrometry in human plasma following deliberate overdose - Li_2010_J.Appl.Toxicol_30_559
Author(s) : Li B , Ricordel I , Schopfer LM , Baud F , Megarbane B , Masson P , Lockridge O
Ref : J Appl Toxicol , 30 :559 , 2010
Abstract : Li_2010_J.Appl.Toxicol_30_559
ESTHER : Li_2010_J.Appl.Toxicol_30_559
PubMedSearch : Li_2010_J.Appl.Toxicol_30_559
PubMedID: 20809544

Title : Detection of adduct on tyrosine 411 of albumin in humans poisoned by dichlorvos - Li_2010_Toxicol.Sci_116_23
Author(s) : Li B , Ricordel I , Schopfer LM , Baud F , Megarbane B , Nachon F , Masson P , Lockridge O
Ref : Toxicol Sci , 116 :23 , 2010
Abstract : Li_2010_Toxicol.Sci_116_23
ESTHER : Li_2010_Toxicol.Sci_116_23
PubMedSearch : Li_2010_Toxicol.Sci_116_23
PubMedID: 20395308

Title : Structural approach to the aging of phosphylated cholinesterases - Masson_2010_Chem.Biol.Interact_187_157
Author(s) : Masson P , Nachon F , Lockridge O
Ref : Chemico-Biological Interactions , 187 :157 , 2010
Abstract : Masson_2010_Chem.Biol.Interact_187_157
ESTHER : Masson_2010_Chem.Biol.Interact_187_157
PubMedSearch : Masson_2010_Chem.Biol.Interact_187_157
PubMedID: 20338153

Title : Reaction of human albumin with aspirin in vitro: mass spectrometric identification of acetylated lysines 199, 402, 519, and 545 - Liyasova_2010_Biochem.Pharmacol_79_784
Author(s) : Liyasova MS , Schopfer LM , Lockridge O
Ref : Biochemical Pharmacology , 79 :784 , 2010
Abstract : Liyasova_2010_Biochem.Pharmacol_79_784
ESTHER : Liyasova_2010_Biochem.Pharmacol_79_784
PubMedSearch : Liyasova_2010_Biochem.Pharmacol_79_784
PubMedID: 19836360

Title : Butyrylcholinesterase for protection from organophosphorus poisons: catalytic complexities and hysteretic behavior - Masson_2010_Arch.Biochem.Biophys_494_107
Author(s) : Masson P , Lockridge O
Ref : Archives of Biochemistry & Biophysics , 494 :107 , 2010
Abstract : Masson_2010_Arch.Biochem.Biophys_494_107
ESTHER : Masson_2010_Arch.Biochem.Biophys_494_107
PubMedSearch : Masson_2010_Arch.Biochem.Biophys_494_107
PubMedID: 20004171

Title : Development of diagnostics in the search for an explanation of aerotoxic syndrome - Schopfer_2010_Anal.Biochem_404_64
Author(s) : Schopfer LM , Furlong CE , Lockridge O
Ref : Analytical Biochemistry , 404 :64 , 2010
Abstract : Schopfer_2010_Anal.Biochem_404_64
ESTHER : Schopfer_2010_Anal.Biochem_404_64
PubMedSearch : Schopfer_2010_Anal.Biochem_404_64
PubMedID: 20447373

Title : Drastic decrease in dopamine receptor levels in the striatum of acetylcholinesterase knock-out mouse - Hrabovska_2010_Chem.Biol.Interact_183_194
Author(s) : Hrabovska A , Farar V , Bernard V , Duysen EG , Brabec J , Lockridge O , Myslivecek J
Ref : Chemico-Biological Interactions , 183 :194 , 2010
Abstract : Hrabovska_2010_Chem.Biol.Interact_183_194
ESTHER : Hrabovska_2010_Chem.Biol.Interact_183_194
PubMedSearch : Hrabovska_2010_Chem.Biol.Interact_183_194
PubMedID: 19818744

Title : Mass spectral characterization of organophosphate-labeled lysine in peptides. - Grigoryan_2009_Anal.Biochem_394_92
Author(s) : Grigoryan H , Li B , Xue W , Grigoryan M , Schopfer LM , Lockridge O
Ref : Analytical Biochemistry , 394 :92 , 2009
Abstract : Grigoryan_2009_Anal.Biochem_394_92
ESTHER : Grigoryan_2009_Anal.Biochem_394_92
PubMedSearch : Grigoryan_2009_Anal.Biochem_394_92
PubMedID: 19596251

Title : Nerve agent analogues that produce authentic soman, sarin, tabun, and cyclohexyl methylphosphonate-modified human butyrylcholinesterase - Gilley_2009_Chem.Res.Toxicol_22_1680
Author(s) : Gilley C , MacDonald M , Nachon F , Schopfer LM , Zhang J , Cashman JR , Lockridge O
Ref : Chemical Research in Toxicology , 22 :1680 , 2009
Abstract : Gilley_2009_Chem.Res.Toxicol_22_1680
ESTHER : Gilley_2009_Chem.Res.Toxicol_22_1680
PubMedSearch : Gilley_2009_Chem.Res.Toxicol_22_1680
PubMedID: 19715348

Title : Intrathecal delivery of fluorescent labeled butyrylcholinesterase to the brains of butyrylcholinesterase knock-out mice: visualization and quantification of enzyme distribution in the brain - Johnson_2009_Neurotoxicol_30_386
Author(s) : Johnson ND , Duysen EG , Lockridge O
Ref : Neurotoxicology , 30 :386 , 2009
Abstract : Johnson_2009_Neurotoxicol_30_386
ESTHER : Johnson_2009_Neurotoxicol_30_386
PubMedSearch : Johnson_2009_Neurotoxicol_30_386
PubMedID: 19442823

Title : Effects of rivastigmine and donepezil on brain acetylcholine levels in acetylcholinesterase-deficient mice - Naik_2009_J.Pharm.Pharm.Sci_12_79
Author(s) : Naik RS , Hartmann J , Kiewert C , Duysen EG , Lockridge O , Klein J
Ref : J Pharm Pharm Sci , 12 :79 , 2009
Abstract : Naik_2009_J.Pharm.Pharm.Sci_12_79
ESTHER : Naik_2009_J.Pharm.Pharm.Sci_12_79
PubMedSearch : Naik_2009_J.Pharm.Pharm.Sci_12_79
PubMedID: 19470293

Title : Nanoimages show disruption of tubulin polymerization by chlorpyrifos oxon: implications for neurotoxicity - Grigoryan_2009_Toxicol.Appl.Pharmacol_240_143
Author(s) : Grigoryan H , Lockridge O
Ref : Toxicol Appl Pharmacol , 240 :143 , 2009
Abstract : Grigoryan_2009_Toxicol.Appl.Pharmacol_240_143
ESTHER : Grigoryan_2009_Toxicol.Appl.Pharmacol_240_143
PubMedSearch : Grigoryan_2009_Toxicol.Appl.Pharmacol_240_143
PubMedID: 19631231

Title : Covalent binding of the organophosphorus agent FP-biotin to tyrosine in eight proteins that have no active site serine - Grigoryan_2009_Chem.Biol.Interact_180_492
Author(s) : Grigoryan H , Li B , Anderson EK , Xue W , Nachon F , Lockridge O , Schopfer LM
Ref : Chemico-Biological Interactions , 180 :492 , 2009
Abstract : Grigoryan_2009_Chem.Biol.Interact_180_492
ESTHER : Grigoryan_2009_Chem.Biol.Interact_180_492
PubMedSearch : Grigoryan_2009_Chem.Biol.Interact_180_492
PubMedID: 19539807

Title : Mass spectrometry identifies multiple organophosphorylated sites on tubulin - Grigoryan_2009_Toxicol.Appl.Pharmacol_240_149
Author(s) : Grigoryan H , Schopfer LM , Peeples ES , Duysen EG , Grigoryan M , Thompson CM , Lockridge O
Ref : Toxicol Appl Pharmacol , 240 :149 , 2009
Abstract : Grigoryan_2009_Toxicol.Appl.Pharmacol_240_149
ESTHER : Grigoryan_2009_Toxicol.Appl.Pharmacol_240_149
PubMedSearch : Grigoryan_2009_Toxicol.Appl.Pharmacol_240_149
PubMedID: 19632257

Title : Tyrosines of human and mouse transferrin covalently labeled by organophosphorus agents: a new motif for binding to proteins that have no active site serine - Li_2009_Toxicol.Sci_107_144
Author(s) : Li B , Schopfer LM , Grigoryan H , Thompson CM , Hinrichs SH , Masson P , Lockridge O
Ref : Toxicol Sci , 107 :144 , 2009
Abstract : Li_2009_Toxicol.Sci_107_144
ESTHER : Li_2009_Toxicol.Sci_107_144
PubMedSearch : Li_2009_Toxicol.Sci_107_144
PubMedID: 18930948

Title : The butyrylcholinesterase knockout mouse a research tool in the study of drug sensitivity, bio-distribution, obesity and Alzheimer's disease - Duysen_2009_Expert.Opin.Drug.Metab.Toxicol_5_523
Author(s) : Duysen EG , Li B , Lockridge O
Ref : Expert Opin Drug Metab Toxicol , 5 :523 , 2009
Abstract : Duysen_2009_Expert.Opin.Drug.Metab.Toxicol_5_523
ESTHER : Duysen_2009_Expert.Opin.Drug.Metab.Toxicol_5_523
PubMedSearch : Duysen_2009_Expert.Opin.Drug.Metab.Toxicol_5_523
PubMedID: 19416087

Title : Adenovirus-transduced human butyrylcholinesterase in mouse blood functions as a bioscavenger of chemical warfare nerve agents - Chilukuri_2009_Mol.Pharmacol_76_612
Author(s) : Chilukuri N , Duysen EG , Parikh K , diTargiani RC , Doctor BP , Lockridge O , Saxena A
Ref : Molecular Pharmacology , 76 :612 , 2009
Abstract : Chilukuri_2009_Mol.Pharmacol_76_612
ESTHER : Chilukuri_2009_Mol.Pharmacol_76_612
PubMedSearch : Chilukuri_2009_Mol.Pharmacol_76_612
PubMedID: 19542320

Title : Carbofuran poisoning detected by mass spectrometry of butyrylcholinesterase adduct in human serum - Li_2009_J.Appl.Toxicol_29_149
Author(s) : Li H , Ricordel I , Tong L , Schopfer LM , Baud F , Megarbane B , Maury E , Masson P , Lockridge O
Ref : J Appl Toxicol , 29 :149 , 2009
Abstract : Li_2009_J.Appl.Toxicol_29_149
ESTHER : Li_2009_J.Appl.Toxicol_29_149
PubMedSearch : Li_2009_J.Appl.Toxicol_29_149
PubMedID: 18937214

Title : Five new naturally occurring mutations of the BCHE gene and frequencies of 12 butyrylcholinesterase alleles in a Brazilian population - Mikami_2008_Pharmacogenet.Genomics_18_213
Author(s) : Mikami LR , Wieseler S , de Souza RLR , Schopfer LM , Nachon F , Lockridge O , Chautard-Freire-Maia EA
Ref : Pharmacogenet Genomics , 18 :213 , 2008
Abstract : Mikami_2008_Pharmacogenet.Genomics_18_213
ESTHER : Mikami_2008_Pharmacogenet.Genomics_18_213
PubMedSearch : Mikami_2008_Pharmacogenet.Genomics_18_213
PubMedID: 18300943

Title : Carbamates with differential mechanism of inhibition toward acetylcholinesterase and butyrylcholinesterase - Darvesh_2008_J.Med.Chem_51_4200
Author(s) : Darvesh S , Darvesh KV , McDonald RS , Mataija D , Walsh R , Mothana S , Lockridge O , Martin E
Ref : Journal of Medicinal Chemistry , 51 :4200 , 2008
Abstract : Darvesh_2008_J.Med.Chem_51_4200
ESTHER : Darvesh_2008_J.Med.Chem_51_4200
PubMedSearch : Darvesh_2008_J.Med.Chem_51_4200
PubMedID: 18570368

Title : Increased hepatotoxicity and cardiac fibrosis in cocaine-treated butyrylcholinesterase knockout mice - Duysen_2008_Basic.Clin.Pharmacol.Toxicol_103_514
Author(s) : Duysen EG , Li B , Carlson M , Li YF , Wieseler S , Hinrichs SH , Lockridge O
Ref : Basic Clin Pharmacol Toxicol , 103 :514 , 2008
Abstract : Duysen_2008_Basic.Clin.Pharmacol.Toxicol_103_514
ESTHER : Duysen_2008_Basic.Clin.Pharmacol.Toxicol_103_514
PubMedSearch : Duysen_2008_Basic.Clin.Pharmacol.Toxicol_103_514
PubMedID: 19067679

Title : Whole body and tissue imaging of the butyrylcholinesterase knockout mouse injected with near infrared dye labeled butyrylcholinesterase - Duysen_2008_Chem.Biol.Interact_175_119
Author(s) : Duysen EG , Lockridge O
Ref : Chemico-Biological Interactions , 175 :119 , 2008
Abstract : Duysen_2008_Chem.Biol.Interact_175_119
ESTHER : Duysen_2008_Chem.Biol.Interact_175_119
PubMedSearch : Duysen_2008_Chem.Biol.Interact_175_119
PubMedID: 18486120

Title : Choline availability and acetylcholine synthesis in the hippocampus of acetylcholinesterase-deficient mice - Hartmann_2008_Neurochem.Int_52_972
Author(s) : Hartmann J , Kiewert C , Duysen EG , Lockridge O , Klein J
Ref : Neurochem Int , 52 :972 , 2008
Abstract : Hartmann_2008_Neurochem.Int_52_972
ESTHER : Hartmann_2008_Neurochem.Int_52_972
PubMedSearch : Hartmann_2008_Neurochem.Int_52_972
PubMedID: 18023504

Title : Kinetic analysis of effector modulation of butyrylcholinesterase-catalysed hydrolysis of acetanilides and homologous esters - Masson_2008_FEBS.J_275_2617
Author(s) : Masson P , Froment MT , Gillon E , Nachon F , Lockridge O , Schopfer LM
Ref : Febs J , 275 :2617 , 2008
Abstract : Masson_2008_FEBS.J_275_2617
ESTHER : Masson_2008_FEBS.J_275_2617
PubMedSearch : Masson_2008_FEBS.J_275_2617
PubMedID: 18422653

Title : Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin - Ding_2008_Chem.Res.Toxicol_21_1787
Author(s) : Ding SJ , Carr J , Carlson JE , Tong L , Xue W , Li Y , Schopfer LM , Li B , Nachon F , Asojo OA , Thompson CM , Hinrichs SH , Masson P , Lockridge O
Ref : Chemical Research in Toxicology , 21 :1787 , 2008
Abstract : Ding_2008_Chem.Res.Toxicol_21_1787
ESTHER : Ding_2008_Chem.Res.Toxicol_21_1787
PubMedSearch : Ding_2008_Chem.Res.Toxicol_21_1787
PubMedID: 18707141

Title : Mass spectrometry identifies covalent binding of soman, sarin, chlorpyrifos oxon, diisopropyl fluorophosphate, and FP-biotin to tyrosines on tubulin: a potential mechanism of long term toxicity by organophosphorus agents - Grigoryan_2008_Chem.Biol.Interact_175_180
Author(s) : Grigoryan H , Schopfer LM , Thompson CM , Terry AV , Masson P , Lockridge O
Ref : Chemico-Biological Interactions , 175 :180 , 2008
Abstract : Grigoryan_2008_Chem.Biol.Interact_175_180
ESTHER : Grigoryan_2008_Chem.Biol.Interact_175_180
PubMedSearch : Grigoryan_2008_Chem.Biol.Interact_175_180
PubMedID: 18502412

Title : The butyrylcholinesterase knockout mouse as a model for human butyrylcholinesterase deficiency - Li_2008_J.Pharmacol.Exp.Ther_324_1146
Author(s) : Li B , Duysen EG , Carlson M , Lockridge O
Ref : Journal of Pharmacology & Experimental Therapeutics , 324 :1146 , 2008
Abstract : Li_2008_J.Pharmacol.Exp.Ther_324_1146
ESTHER : Li_2008_J.Pharmacol.Exp.Ther_324_1146
PubMedSearch : Li_2008_J.Pharmacol.Exp.Ther_324_1146
PubMedID: 18056867

Title : Lamellipodin proline rich peptides associated with native plasma butyrylcholinesterase tetramers - Li_2008_Biochem.J_411_425
Author(s) : Li H , Schopfer LM , Masson P , Lockridge O
Ref : Biochemical Journal , 411 :425 , 2008
Abstract : Li_2008_Biochem.J_411_425
ESTHER : Li_2008_Biochem.J_411_425
PubMedSearch : Li_2008_Biochem.J_411_425
PubMedID: 18076380

Title : Fast affinity purification coupled with mass spectrometry for identifying organophosphate labeled plasma butyrylcholinesterase - Li_2008_Chem.Biol.Interact_175_68
Author(s) : Li H , Tong L , Schopfer LM , Masson P , Lockridge O
Ref : Chemico-Biological Interactions , 175 :68 , 2008
Abstract : Li_2008_Chem.Biol.Interact_175_68
ESTHER : Li_2008_Chem.Biol.Interact_175_68
PubMedSearch : Li_2008_Chem.Biol.Interact_175_68
PubMedID: 18586231

Title : Binding and hydrolysis of soman by human serum albumin - Li_2008_Chem.Res.Toxicol_21_421
Author(s) : Li B , Nachon F , Froment MT , Verdier L , Debouzy JC , Brasme B , Gillon E , Schopfer LM , Lockridge O , Masson P
Ref : Chemical Research in Toxicology , 21 :421 , 2008
Abstract : Li_2008_Chem.Res.Toxicol_21_421
ESTHER : Li_2008_Chem.Res.Toxicol_21_421
PubMedSearch : Li_2008_Chem.Res.Toxicol_21_421
PubMedID: 18163544

Title : Pseudo-esterase activity of human albumin: slow turnover on tyrosine 411 and stable acetylation of 82 residues including 59 lysines - Lockridge_2008_J.Biol.Chem_283_22582
Author(s) : Lockridge O , Xue W , Gaydess A , Grigoryan H , Ding SJ , Schopfer LM , Hinrichs SH , Masson P
Ref : Journal of Biological Chemistry , 283 :22582 , 2008
Abstract : Lockridge_2008_J.Biol.Chem_283_22582
ESTHER : Lockridge_2008_J.Biol.Chem_283_22582
PubMedSearch : Lockridge_2008_J.Biol.Chem_283_22582
PubMedID: 18577514

Title : Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation - Carletti_2008_J.Am.Chem.Soc_130_16011
Author(s) : Carletti E , Li H , Li B , Ekstrom F , Nicolet Y , Loiodice M , Gillon E , Froment MT , Lockridge O , Schopfer LM , Masson P , Nachon F
Ref : Journal of the American Chemical Society , 130 :16011 , 2008
Abstract : Carletti_2008_J.Am.Chem.Soc_130_16011
ESTHER : Carletti_2008_J.Am.Chem.Soc_130_16011
PubMedSearch : Carletti_2008_J.Am.Chem.Soc_130_16011
PubMedID: 18975951
Gene_locus related to this paper: human-BCHE , mouse-ACHE

Title : The butyrylcholinesterase knockout mouse is obese on a high-fat diet - Li_2008_Chem.Biol.Interact_175_88
Author(s) : Li B , Duysen EG , Lockridge O
Ref : Chemico-Biological Interactions , 175 :88 , 2008
Abstract : Li_2008_Chem.Biol.Interact_175_88
ESTHER : Li_2008_Chem.Biol.Interact_175_88
PubMedSearch : Li_2008_Chem.Biol.Interact_175_88
PubMedID: 18452903

Title : A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters - Masson_2008_Chem.Biol.Interact_175_273
Author(s) : Masson P , Nachon F , Broomfield CA , Lenz DE , Verdier L , Schopfer LM , Lockridge O
Ref : Chemico-Biological Interactions , 175 :273 , 2008
Abstract : Masson_2008_Chem.Biol.Interact_175_273
ESTHER : Masson_2008_Chem.Biol.Interact_175_273
PubMedSearch : Masson_2008_Chem.Biol.Interact_175_273
PubMedID: 18508040

Title : Adenovirus-mediated gene transfer of human butyrylcholinesterase results in persistent high-level transgene expression in vivo - Chilukuri_2008_Chem.Biol.Interact_175_327
Author(s) : Chilukuri N , Duysen EG , Parikh K , Sun W , Doctor BP , Lockridge O , Saxena A
Ref : Chemico-Biological Interactions , 175 :327 , 2008
Abstract : Chilukuri_2008_Chem.Biol.Interact_175_327
ESTHER : Chilukuri_2008_Chem.Biol.Interact_175_327
PubMedSearch : Chilukuri_2008_Chem.Biol.Interact_175_327
PubMedID: 18499092

Title : Expression of three naturally occurring genetic variants (G75R, E90D, I99M) of the BCHE gene of human butyrylcholinesterase - Mikami_2007_Pharmacogenet.Genomics_17_681
Author(s) : Mikami LR , Wieseler S , de Souza RLR , Schopfer LM , Lockridge O , Chautard-Freire-Maia EA
Ref : Pharmacogenet Genomics , 17 :681 , 2007
Abstract : Mikami_2007_Pharmacogenet.Genomics_17_681
ESTHER : Mikami_2007_Pharmacogenet.Genomics_17_681
PubMedSearch : Mikami_2007_Pharmacogenet.Genomics_17_681
PubMedID: 17700357

Title : Neuropathological and immunochemical studies of brain parenchyma in acetylcholinesterase knockout mice: implications in Alzheimer's disease - Rice_2007_J.Alzheimers.Dis_11_481
Author(s) : Rice SG , Nowak L , Duysen EG , Lockridge O , Lahiri DK , Reyes PF
Ref : J Alzheimers Dis , 11 :481 , 2007
Abstract : Rice_2007_J.Alzheimers.Dis_11_481
ESTHER : Rice_2007_J.Alzheimers.Dis_11_481
PubMedSearch : Rice_2007_J.Alzheimers.Dis_11_481
PubMedID: 17656828

Title : Adaptation to excess acetylcholine by downregulation of adrenoceptors and muscarinic receptors in lungs of acetylcholinesterase knockout mice - Myslivecek_2007_Naunyn.Schmiedebergs.Arch.Pharmacol_376_83
Author(s) : Myslivecek J , Duysen EG , Lockridge O
Ref : Naunyn Schmiedebergs Arch Pharmacol , 376 :83 , 2007
Abstract : Myslivecek_2007_Naunyn.Schmiedebergs.Arch.Pharmacol_376_83
ESTHER : Myslivecek_2007_Naunyn.Schmiedebergs.Arch.Pharmacol_376_83
PubMedSearch : Myslivecek_2007_Naunyn.Schmiedebergs.Arch.Pharmacol_376_83
PubMedID: 17805515

Title : Crystallization and X-ray structure of full-length recombinant human butyrylcholinesterase - Ngamelue_2007_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_63_723
Author(s) : Ngamelue MN , Homma K , Lockridge O , Asojo OA
Ref : Acta Crystallographica Sect F Struct Biol Cryst Commun , 63 :723 , 2007
Abstract : Ngamelue_2007_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_63_723
ESTHER : Ngamelue_2007_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_63_723
PubMedSearch : Ngamelue_2007_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_63_723
PubMedID: 17768338
Gene_locus related to this paper: human-BCHE

Title : Comparison of cognitive functions between people with silent and wild-type butyrylcholinesterase - Manoharan_2007_J.Neural.Transm.(Vienna)_114_939
Author(s) : Manoharan I , Kuznetsova A , Fisk JD , Boopathy R , Lockridge O , Darvesh S
Ref : J Neural Transm (Vienna) , 114 :939 , 2007
Abstract : Manoharan_2007_J.Neural.Transm.(Vienna)_114_939
ESTHER : Manoharan_2007_J.Neural.Transm.(Vienna)_114_939
PubMedSearch : Manoharan_2007_J.Neural.Transm.(Vienna)_114_939
PubMedID: 17318303

Title : Sensitivity of butyrylcholinesterase knockout mice to (--)-huperzine A and donepezil suggests humans with butyrylcholinesterase deficiency may not tolerate these Alzheimer's disease drugs and indicates butyrylcholinesterase function in neurotransmission - Duysen_2007_Toxicology_233_60
Author(s) : Duysen EG , Li B , Darvesh S , Lockridge O
Ref : Toxicology , 233 :60 , 2007
Abstract : Duysen_2007_Toxicology_233_60
ESTHER : Duysen_2007_Toxicology_233_60
PubMedSearch : Duysen_2007_Toxicology_233_60
PubMedID: 17194517

Title : Matrix-assisted laser desorption\/ionization time-of-flight mass spectrometry assay for organophosphorus toxicants bound to human albumin at Tyr411 - Li_2007_Anal.Biochem_361_263
Author(s) : Li B , Schopfer LM , Hinrichs SH , Masson P , Lockridge O
Ref : Analytical Biochemistry , 361 :263 , 2007
Abstract : Li_2007_Anal.Biochem_361_263
ESTHER : Li_2007_Anal.Biochem_361_263
PubMedSearch : Li_2007_Anal.Biochem_361_263
PubMedID: 17188226

Title : A novel method for purifying recombinant human host defense cathelicidin LL-37 by utilizing its inherent property of aggregation - Li_2007_Protein.Expr.Purif_54_157
Author(s) : Li Y , Li X , Li H , Lockridge O , Wang G
Ref : Protein Expr Purif , 54 :157 , 2007
Abstract : Li_2007_Protein.Expr.Purif_54_157
ESTHER : Li_2007_Protein.Expr.Purif_54_157
PubMedSearch : Li_2007_Protein.Expr.Purif_54_157
PubMedID: 17382559

Title : Hydrolysis of oxo- and thio-esters by human butyrylcholinesterase - Masson_2007_Biochim.Biophys.Acta_1774_16
Author(s) : Masson P , Froment MT , Gillon E , Nachon F , Lockridge O , Schopfer LM
Ref : Biochimica & Biophysica Acta , 1774 :16 , 2007
Abstract : Masson_2007_Biochim.Biophys.Acta_1774_16
ESTHER : Masson_2007_Biochim.Biophys.Acta_1774_16
PubMedSearch : Masson_2007_Biochim.Biophys.Acta_1774_16
PubMedID: 17182295

Title : Aging pathways for organophosphate-inhibited human butyrylcholinesterase, including novel pathways for isomalathion, resolved by mass spectrometry - Li_2007_Toxicol.Sci_100_136
Author(s) : Li H , Schopfer LM , Nachon F , Froment MT , Masson P , Lockridge O
Ref : Toxicol Sci , 100 :136 , 2007
Abstract : Li_2007_Toxicol.Sci_100_136
ESTHER : Li_2007_Toxicol.Sci_100_136
PubMedSearch : Li_2007_Toxicol.Sci_100_136
PubMedID: 17698511

Title : Aryl acylamidase activity of human serum albumin with o-nitrotrifluoroacetanilide as the substrate - Masson_2007_J.Enzyme.Inhib.Med.Chem_22_463
Author(s) : Masson P , Froment MT , Darvesh S , Schopfer LM , Lockridge O
Ref : J Enzyme Inhib Med Chem , 22 :463 , 2007
Abstract : Masson_2007_J.Enzyme.Inhib.Med.Chem_22_463
ESTHER : Masson_2007_J.Enzyme.Inhib.Med.Chem_22_463
PubMedSearch : Masson_2007_J.Enzyme.Inhib.Med.Chem_22_463
PubMedID: 17847714

Title : Excessive hippocampal acetylcholine levels in acetylcholinesterase-deficient mice are moderated by butyrylcholinesterase activity - Hartmann_2007_J.Neurochem_100_1421
Author(s) : Hartmann J , Kiewert C , Duysen EG , Lockridge O , Greig NH , Klein J
Ref : Journal of Neurochemistry , 100 :1421 , 2007
Abstract : Hartmann_2007_J.Neurochem_100_1421
ESTHER : Hartmann_2007_J.Neurochem_100_1421
PubMedSearch : Hartmann_2007_J.Neurochem_100_1421
PubMedID: 17212694

Title : A medical health report on individuals with silent butyrylcholinesterase in the Vysya community of India - Manoharan_2007_Clin.Chim.Acta_378_128
Author(s) : Manoharan I , Boopathy R , Darvesh S , Lockridge O
Ref : Clinica Chimica Acta , 378 :128 , 2007
Abstract : Manoharan_2007_Clin.Chim.Acta_378_128
ESTHER : Manoharan_2007_Clin.Chim.Acta_378_128
PubMedSearch : Manoharan_2007_Clin.Chim.Acta_378_128
PubMedID: 17182021

Title : Protection from the toxicity of diisopropylfluorophosphate by adeno-associated virus expressing acetylcholinesterase - Li_2006_Toxicol.Appl.Pharmacol_214_152
Author(s) : Li B , Duysen EG , Poluektova LY , Murrin LC , Lockridge O
Ref : Toxicol Appl Pharmacol , 214 :152 , 2006
Abstract : Li_2006_Toxicol.Appl.Pharmacol_214_152
ESTHER : Li_2006_Toxicol.Appl.Pharmacol_214_152
PubMedSearch : Li_2006_Toxicol.Appl.Pharmacol_214_152
PubMedID: 16443250

Title : Mutant of Bungarus fasciatus acetylcholinesterase with low affinity and low hydrolase activity toward organophosphorus esters - Poyot_2006_Biochim.Biophys.Acta_1764_1470
Author(s) : Poyot T , Nachon F , Froment MT , Loiodice M , Wieseler S , Schopfer LM , Lockridge O , Masson P
Ref : Biochimica & Biophysica Acta , 1764 :1470 , 2006
Abstract : Poyot_2006_Biochim.Biophys.Acta_1764_1470
ESTHER : Poyot_2006_Biochim.Biophys.Acta_1764_1470
PubMedSearch : Poyot_2006_Biochim.Biophys.Acta_1764_1470
PubMedID: 16962835

Title : Production of the butyrylcholinesterase knockout mouse - Li_2006_J.Mol.Neurosci_30_193
Author(s) : Li B , Duysen EG , Saunders TL , Lockridge O
Ref : Journal of Molecular Neuroscience , 30 :193 , 2006
Abstract : Li_2006_J.Mol.Neurosci_30_193
ESTHER : Li_2006_J.Mol.Neurosci_30_193
PubMedSearch : Li_2006_J.Mol.Neurosci_30_193
PubMedID: 17192674

Title : Markers of organophosphate exposure in human serum - Wieseler_2006_J.Mol.Neurosci_30_93
Author(s) : Wieseler S , Schopfer LM , Lockridge O
Ref : Journal of Molecular Neuroscience , 30 :93 , 2006
Abstract : Wieseler_2006_J.Mol.Neurosci_30_93
ESTHER : Wieseler_2006_J.Mol.Neurosci_30_93
PubMedSearch : Wieseler_2006_J.Mol.Neurosci_30_93
PubMedID: 17192643

Title : Naturally occurring mutation Leu307Pro of human butyrylcholinesterase in the Vysya community of India - Manoharan_2006_Pharmacogenet.Genomics_16_461
Author(s) : Manoharan I , Wieseler S , Layer PG , Lockridge O , Boopathy R
Ref : Pharmacogenet Genomics , 16 :461 , 2006
Abstract : Manoharan_2006_Pharmacogenet.Genomics_16_461
ESTHER : Manoharan_2006_Pharmacogenet.Genomics_16_461
PubMedSearch : Manoharan_2006_Pharmacogenet.Genomics_16_461
PubMedID: 16788378
Gene_locus related to this paper: human-BCHE

Title : Phenotype comparison of three acetylcholinesterase knockout strains - Duysen_2006_J.Mol.Neurosci_30_91
Author(s) : Duysen EG , Lockridge O
Ref : Journal of Molecular Neuroscience , 30 :91 , 2006
Abstract : Duysen_2006_J.Mol.Neurosci_30_91
ESTHER : Duysen_2006_J.Mol.Neurosci_30_91
PubMedSearch : Duysen_2006_J.Mol.Neurosci_30_91
PubMedID: 17192642

Title : A mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the alpha,beta-hydrolase fold protein family - De Jaco_2006_J.Biol.Chem_281_9667
Author(s) : De Jaco A , Comoletti D , Kovarik Z , Gaietta G , Radic Z , Lockridge O , Ellisman MH , Taylor P
Ref : Journal of Biological Chemistry , 281 :9667 , 2006
Abstract : De Jaco_2006_J.Biol.Chem_281_9667
ESTHER : De Jaco_2006_J.Biol.Chem_281_9667
PubMedSearch : De Jaco_2006_J.Biol.Chem_281_9667
PubMedID: 16434405

Title : Gene transfer of acetylcholinesterase protects the knockout mouse from the toxicity of DFP - Li_2006_J.Mol.Neurosci_30_79
Author(s) : Li B , Duysen EG , Lockridge O
Ref : Journal of Molecular Neuroscience , 30 :79 , 2006
Abstract : Li_2006_J.Mol.Neurosci_30_79
ESTHER : Li_2006_J.Mol.Neurosci_30_79
PubMedSearch : Li_2006_J.Mol.Neurosci_30_79
PubMedID: 17192637

Title : Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma - Li_2005_Biochem.Pharmacol_70_1673
Author(s) : Li B , Sedlacek M , Manoharan I , Boopathy R , Duysen EG , Masson P , Lockridge O
Ref : Biochemical Pharmacology , 70 :1673 , 2005
Abstract : Li_2005_Biochem.Pharmacol_70_1673
ESTHER : Li_2005_Biochem.Pharmacol_70_1673
PubMedSearch : Li_2005_Biochem.Pharmacol_70_1673
PubMedID: 16213467

Title : Structural data on the aging of diethylphosphoryl-butyrylcholinesterase -
Author(s) : Nachon F , Asojo OA , Borgstahl GE , Masson P , Lockridge O
Ref : Chemico-Biological Interactions , 157-158 :408 , 2005
PubMedID: 16429549

Title : Characteristic mass spectral fragments of the organophosphorus agent FP-biotin and FP-biotinylated peptides from trypsin and bovine albumin (Tyr410) - Schopfer_2005_Anal.Biochem_345_122
Author(s) : Schopfer LM , Champion MM , Tamblyn N , Thompson CM , Lockridge O
Ref : Analytical Biochemistry , 345 :122 , 2005
Abstract : Schopfer_2005_Anal.Biochem_345_122
ESTHER : Schopfer_2005_Anal.Biochem_345_122
PubMedSearch : Schopfer_2005_Anal.Biochem_345_122
PubMedID: 16125664

Title : Identification of organophosphate-reactive proteins by tandem mass spectrometry -
Author(s) : Li H , Schopfer LM , Spaulding R , Thompson CM , Lockridge O
Ref : Chemico-Biological Interactions , 157-158 :383 , 2005
PubMedID: 16429512

Title : Reaction kinetics of biotinylated organophosphorus toxicant, FP-biotin, with human acetylcholinesterase and human butyrylcholinesterase - Schopfer_2005_Chem.Res.Toxicol_18_747
Author(s) : Schopfer LM , Voelker T , Bartels CF , Thompson CM , Lockridge O
Ref : Chemical Research in Toxicology , 18 :747 , 2005
Abstract : Schopfer_2005_Chem.Res.Toxicol_18_747
ESTHER : Schopfer_2005_Chem.Res.Toxicol_18_747
PubMedSearch : Schopfer_2005_Chem.Res.Toxicol_18_747
PubMedID: 15833035

Title : Delivery of human acetylcholinesterase by adeno-associated virus to the acetylcholinesterase knockout mouse - Hrabovska_2005_Chem.Biol.Interact_157-158_71
Author(s) : Hrabovska A , Duysen EG , Sanders JD , Murrin LC , Lockridge O
Ref : Chemico-Biological Interactions , 157-158 :71 , 2005
Abstract : Hrabovska_2005_Chem.Biol.Interact_157-158_71
ESTHER : Hrabovska_2005_Chem.Biol.Interact_157-158_71
PubMedSearch : Hrabovska_2005_Chem.Biol.Interact_157-158_71
PubMedID: 16243306

Title : Large scale purification of butyrylcholinesterase from human plasma suitable for injection into monkeys\; A potential new therapeutic for protection against cocaine end nerve agent toxicity - Lockridge_2005_J.Med.Chem.Biol.Radiol.Def_3_nihms5095
Author(s) : Lockridge O , Schopfer LM , Winger G , Woods JH
Ref : Journal of Medicinal Chemistryical Biology Radiol Def , 3 :nihms5095 , 2005
Abstract : Lockridge_2005_J.Med.Chem.Biol.Radiol.Def_3_nihms5095
ESTHER : Lockridge_2005_J.Med.Chem.Biol.Radiol.Def_3_nihms5095
PubMedSearch : Lockridge_2005_J.Med.Chem.Biol.Radiol.Def_3_nihms5095
PubMedID: 16788731

Title : Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry - Peeples_2005_Toxicol.Sci_83_303
Author(s) : Peeples ES , Schopfer LM , Duysen EG , Spaulding R , Voelker T , Thompson CM , Lockridge O
Ref : Toxicol Sci , 83 :303 , 2005
Abstract : Peeples_2005_Toxicol.Sci_83_303
ESTHER : Peeples_2005_Toxicol.Sci_83_303
PubMedSearch : Peeples_2005_Toxicol.Sci_83_303
PubMedID: 15525694

Title : Intraperitoneal administration of 340 kDa human plasma butyrylcholinesterase increases the level of the enzyme in the cerebrospinal fluid of rats - Saez-Valero_2005_Neurosci.Lett_383_93
Author(s) : Saez-Valero J , de Gracia JA , Lockridge O
Ref : Neuroscience Letters , 383 :93 , 2005
Abstract : Saez-Valero_2005_Neurosci.Lett_383_93
ESTHER : Saez-Valero_2005_Neurosci.Lett_383_93
PubMedSearch : Saez-Valero_2005_Neurosci.Lett_383_93
PubMedID: 15936518

Title : Life without acetylcholinesterase: the implications of cholinesterase inhibitor toxicity in AChE-knockout mice - Lockridge_2005_Environ.Toxicol.Pharmacol_19_463
Author(s) : Lockridge O , Duysen EG , Voelker T , Thompson CM , Schopfer LM
Ref : Environ Toxicol Pharmacol , 19 :463 , 2005
Abstract : Lockridge_2005_Environ.Toxicol.Pharmacol_19_463
ESTHER : Lockridge_2005_Environ.Toxicol.Pharmacol_19_463
PubMedSearch : Lockridge_2005_Environ.Toxicol.Pharmacol_19_463
PubMedID: 21783513

Title : Hysteresis of butyrylcholinesterase in the approach to steady-state kinetics - Masson_2005_Chem.Biol.Interact_157-158_143
Author(s) : Masson P , Schopfer LM , Froment MT , Debouzy JC , Nachon F , Gillon E , Lockridge O , Hrabovska A , Goldstein BN
Ref : Chemico-Biological Interactions , 157-158 :143 , 2005
Abstract : Masson_2005_Chem.Biol.Interact_157-158_143
ESTHER : Masson_2005_Chem.Biol.Interact_157-158_143
PubMedSearch : Masson_2005_Chem.Biol.Interact_157-158_143
PubMedID: 16256969

Title : Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging - Nachon_2005_Biochemistry_44_1154
Author(s) : Nachon F , Asojo OA , Borgstahl GE , Masson P , Lockridge O
Ref : Biochemistry , 44 :1154 , 2005
Abstract : Nachon_2005_Biochemistry_44_1154
ESTHER : Nachon_2005_Biochemistry_44_1154
PubMedSearch : Nachon_2005_Biochemistry_44_1154
PubMedID: 15667209
Gene_locus related to this paper: human-BCHE

Title : Poster (82) Acetylcholinesterase wild-type and knock-out mice show different locomotor activity after scopolamine injection -
Author(s) : Hrabovska A , Lockridge O
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :364 , 2004
PubMedID:

Title : Mutants of human butyrylcholinesterase with organophosphate hydrolase activity\; evidence that His117 is a general base catalyst for hydrolysis of echothiophate - Schopfer_2004_J.Med.Chem.Biol.Radiol.Def_2_1
Author(s) : Schopfer LM , Boeck AT , Broomfield CA , Lockridge O
Ref : Journal of Medicinal Chemistryical Biology Radiol Def , 2 :1 , 2004
Abstract : Schopfer_2004_J.Med.Chem.Biol.Radiol.Def_2_1
ESTHER : Schopfer_2004_J.Med.Chem.Biol.Radiol.Def_2_1
PubMedSearch : Schopfer_2004_J.Med.Chem.Biol.Radiol.Def_2_1
PubMedID:

Title : Poster (90) Acetylcholinesterase knockout mice are resistant oxotremorine-induced hypothermia and pilocarpine-induced seizures -
Author(s) : Li B , Duysen EG , Lockridge O
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :368 , 2004
PubMedID:

Title : Muscarinic acetylcholine receptors are down-regulated in acetylcholinesterase knockout mice. -
Author(s) : Li B , Duysen EG , Lockridge O
Ref : Cholinergic Mechanisms, CRC Press :619 , 2004
PubMedID:

Title : Poster (93) How do the crystal structures of human butyrylcholinesterase compare to torpedo californica acetylcholinesterases structures? -
Author(s) : Nachon F , Nicolet Y , Masson P , Lockridge O , Fontecilla-Camps JC
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :369 , 2004
PubMedID:

Title : Resistance to organophosphorus agent toxicity in transgenic mice expressing the G117H mutant of human butyrylcholinesterase - Wang_2004_Toxicol.Appl.Pharmacol_196_356
Author(s) : Wang Y , Boeck AT , Duysen EG , Van Keuren M , Saunders TL , Lockridge O
Ref : Toxicol Appl Pharmacol , 196 :356 , 2004
Abstract : Wang_2004_Toxicol.Appl.Pharmacol_196_356
ESTHER : Wang_2004_Toxicol.Appl.Pharmacol_196_356
PubMedSearch : Wang_2004_Toxicol.Appl.Pharmacol_196_356
PubMedID: 15094306

Title : Hysteretic behavior of butyrylcholinesterase: Kinetic curiosity or catalytically and physiologicaly significant? -
Author(s) : Masson P , Froment MT , Nachon F , Lockridge O , Schopfer LM
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :191 , 2004
PubMedID:

Title : Poster (20) Hysteretic behavior of butyrylcholinesterase : kinetic curiosity or catalytically and physiologically significant? -
Author(s) : Masson P , Froment MT , Nachon F , Lockridge O , Schopfer LM
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :331 , 2004
PubMedID:

Title : Helicobacter hepaticus infection in acetylcholinesterase knockout mice results in severe intestinal distension -
Author(s) : Duysen EG , Kolar CH , Lockridge O
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :301 , 2004
PubMedID:

Title : Acetylcholinesterase wild-type and knockout mice show different locomotor activity after scopolamine injection -
Author(s) : Hrabovska A , Lockridge O
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :315 , 2004
PubMedID:

Title : Reduced acetylcholine receptor density, morphological remodeling, and butyrylcholinesterase activity can sustain muscle function in acetylcholinesterase knockout mice - Adler_2004_Muscle.Nerve_30_317
Author(s) : Adler M , Manley HA , Purcell AL , Deshpande SS , Hamilton TA , Kan RK , Oyler G , Lockridge O , Duysen EG , Sheridan RE
Ref : Muscle & Nerve , 30 :317 , 2004
Abstract : Adler_2004_Muscle.Nerve_30_317
ESTHER : Adler_2004_Muscle.Nerve_30_317
PubMedSearch : Adler_2004_Muscle.Nerve_30_317
PubMedID: 15318343

Title : Poster (49) Crystallographic basis for substrate\/product exchange in cholinesterases. -
Author(s) : Nicolet Y , Lockridge O , Masson P , Fontecilla-Camps JC , Nachon F
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :347 , 2004
PubMedID:

Title : Phenotype of the adult acetylcholinesterase-deficient mouse. -
Author(s) : Duysen EG , Stribley JA , Fry DL , Hinrichs SH , Lockridge O
Ref : Cholinergic Mechanisms, CRC Press :559 , 2004
PubMedID:

Title : Rate-determining step of butyrylcholinesterase-catalyzed hydrolysis of benzoylcholine and benzoylthiocholine. Volumetric study of wild-type and D70G mutant behavior - Masson_2004_Eur.J.Biochem_271_1980
Author(s) : Masson P , Bec N , Froment MT , Nachon F , Balny C , Lockridge O , Schopfer LM
Ref : European Journal of Biochemistry , 271 :1980 , 2004
Abstract : Masson_2004_Eur.J.Biochem_271_1980
ESTHER : Masson_2004_Eur.J.Biochem_271_1980
PubMedSearch : Masson_2004_Eur.J.Biochem_271_1980
PubMedID: 15128307

Title : Poster (55) Life without acetylcholinesterase -
Author(s) : Lockridge O , Duysen EG , Li B , Hrabovska A
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :350 , 2004
PubMedID:

Title : Impaired formation of the inner retina in an AChE knockout mouse results in degeneration of all photoreceptors - Bytyqi_2004_Eur.J.Neurosci_20_2953
Author(s) : Bytyqi AH , Lockridge O , Duysen E , Wang Y , Wolfrum U , Layer PG
Ref : European Journal of Neuroscience , 20 :2953 , 2004
Abstract : Bytyqi_2004_Eur.J.Neurosci_20_2953
ESTHER : Bytyqi_2004_Eur.J.Neurosci_20_2953
PubMedSearch : Bytyqi_2004_Eur.J.Neurosci_20_2953
PubMedID: 15579149

Title : Damped oscillatory hysteretic behaviour of butyrylcholinesterase with benzoylcholine as substrate - Masson_2004_Eur.J.Biochem_271_220
Author(s) : Masson P , Goldstein BN , Debouzy JC , Froment MT , Lockridge O , Schopfer LM
Ref : European Journal of Biochemistry , 271 :220 , 2004
Abstract : Masson_2004_Eur.J.Biochem_271_220
ESTHER : Masson_2004_Eur.J.Biochem_271_220
PubMedSearch : Masson_2004_Eur.J.Biochem_271_220
PubMedID: 14686935

Title : Dramatic depletion of cell surface muscarinic receptor due to limited delivery from intracytoplasmic stores in neurons of acetylcholinesterase-deficient mice. -
Author(s) : Bernard V , Brana C , Liste I , Lockridge O , Bloch B
Ref : Cholinergic Mechanisms, CRC Press :477 , 2004
PubMedID:

Title : Poster (59) Complete postnatal degeneration of the photoreceptor layer in an AChE knockout mouse -
Author(s) : Bytyqi AH , Duysen EG , Lockridge O , Layer PG
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :352 , 2004
PubMedID:

Title : Poster (60) Early distortion of network formation in the inner retina of an AChE knockout mouse -
Author(s) : Bytyqi AH , Paraoanu LE , Duysen EG , Lockridge O , Layer PG
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :353 , 2004
PubMedID:

Title : X-Ray structures of native and soman-aged human butyrylcholinesterase. -
Author(s) : Nachon F , Nicolet Y , Masson P , Lockridge O , Fontecilla-Camps JC
Ref : Cholinergic Mechanisms, CRC Press :165 , 2004
PubMedID:

Title : Screening assays for cholinesterases resistant to inhibition by organophosphorus toxicants - Wang_2004_Anal.Biochem_329_131
Author(s) : Wang Y , Schopfer LM , Duysen EG , Nachon F , Masson P , Lockridge O
Ref : Analytical Biochemistry , 329 :131 , 2004
Abstract : Wang_2004_Anal.Biochem_329_131
ESTHER : Wang_2004_Anal.Biochem_329_131
PubMedSearch : Wang_2004_Anal.Biochem_329_131
PubMedID: 15136175

Title : Acetylcholinesterase knockout mice have increased sensitivity to scopolamine and atropine. -
Author(s) : Hrabovska A , Duysen EG , Lockridge O
Ref : Cholinergic Mechanisms, CRC Press :593 , 2004
PubMedID:

Title : Poster (78) H. hepaticus infection in acetylcholinesterase knockout mice results in severe intestinal distension. -
Author(s) : Duysen EG , Kolar CH , Lockridge O
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :362 , 2004
PubMedID:

Title : Application of directed evolution technology to optimize the cocaine hydrolase activity of human butyrylcholinesterase -
Author(s) : Pancook JD , Pecht G , Ader M , Mosko M , Lockridge O , Watkins JD
Ref : FASEB Journal , 17 :A565 , 2003
PubMedID:

Title : Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products - Nicolet_2003_J.Biol.Chem_278_41141
Author(s) : Nicolet Y , Lockridge O , Masson P , Fontecilla-Camps JC , Nachon F
Ref : Journal of Biological Chemistry , 278 :41141 , 2003
Abstract : Nicolet_2003_J.Biol.Chem_278_41141
ESTHER : Nicolet_2003_J.Biol.Chem_278_41141
PubMedSearch : Nicolet_2003_J.Biol.Chem_278_41141
PubMedID: 12869558
Gene_locus related to this paper: human-BCHE

Title : Regulation of muscarinic acetylcholine receptor function in acetylcholinesterase knockout mice - Li_2003_Pharmacol.Biochem.Behav_74_977
Author(s) : Li B , Duysen EG , Volpicelli-Daley LA , Levey AI , Lockridge O
Ref : Pharmacol Biochem Behav , 74 :977 , 2003
Abstract : Li_2003_Pharmacol.Biochem.Behav_74_977
ESTHER : Li_2003_Pharmacol.Biochem.Behav_74_977
PubMedSearch : Li_2003_Pharmacol.Biochem.Behav_74_977
PubMedID: 12667913

Title : Altered hippocampal muscarinic receptors in acetylcholinesterase-deficient mice - Volpicelli-Daley_2003_Ann.Neurol_53_788
Author(s) : Volpicelli-Daley LA , Duysen EG , Lockridge O , Levey AI
Ref : Annals of Neurology , 53 :788 , 2003
Abstract : Volpicelli-Daley_2003_Ann.Neurol_53_788
ESTHER : Volpicelli-Daley_2003_Ann.Neurol_53_788
PubMedSearch : Volpicelli-Daley_2003_Ann.Neurol_53_788
PubMedID: 12783426

Title : Altered striatal function and muscarinic cholinergic receptors in acetylcholinesterase knockout mice - Volpicelli-Daley_2003_Mol.Pharmacol_64_1309
Author(s) : Volpicelli-Daley LA , Hrabovska A , Duysen EG , Ferguson SM , Blakely RD , Lockridge O , Levey AI
Ref : Molecular Pharmacology , 64 :1309 , 2003
Abstract : Volpicelli-Daley_2003_Mol.Pharmacol_64_1309
ESTHER : Volpicelli-Daley_2003_Mol.Pharmacol_64_1309
PubMedSearch : Volpicelli-Daley_2003_Mol.Pharmacol_64_1309
PubMedID: 14645660

Title : Dramatic depletion of cell surface m2 muscarinic receptor due to limited delivery from intracytoplasmic stores in neurons of acetylcholinesterase-deficient mice - Bernard_2003_Mol.Cell.Neurosci_23_121
Author(s) : Bernard V , Brana C , Liste I , Lockridge O , Bloch B
Ref : Molecular & Cellular Neurosciences , 23 :121 , 2003
Abstract : Bernard_2003_Mol.Cell.Neurosci_23_121
ESTHER : Bernard_2003_Mol.Cell.Neurosci_23_121
PubMedSearch : Bernard_2003_Mol.Cell.Neurosci_23_121
PubMedID: 12799142

Title : High activity of human butyrylcholinesterase at low pH in the presence of excess butyrylthiocholine - Masson_2003_Eur.J.Biochem_270_315
Author(s) : Masson P , Nachon F , Bartels CF , Froment MT , Ribes F , Matthews C , Lockridge O
Ref : European Journal of Biochemistry , 270 :315 , 2003
Abstract : Masson_2003_Eur.J.Biochem_270_315
ESTHER : Masson_2003_Eur.J.Biochem_270_315
PubMedSearch : Masson_2003_Eur.J.Biochem_270_315
PubMedID: 12605682

Title : Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept) to cholinesterases - Saxena_2003_Eur.J.Biochem_270_4447
Author(s) : Saxena A , Fedorko JM , Vinayaka CR , Medhekar R , Radic Z , Taylor P , Lockridge O , Doctor BP
Ref : European Journal of Biochemistry , 270 :4447 , 2003
Abstract : Saxena_2003_Eur.J.Biochem_270_4447
ESTHER : Saxena_2003_Eur.J.Biochem_270_4447
PubMedSearch : Saxena_2003_Eur.J.Biochem_270_4447
PubMedID: 14622273

Title : Naturally occurring mutation, Asp70his, in human butyrylcholinesterase - Boeck_2002_Ann.Clin.Biochem_39_154
Author(s) : Boeck AT , Fry DL , Sastre A , Lockridge O
Ref : Annals of Clinical Biochemistry , 39 :154 , 2002
Abstract : Boeck_2002_Ann.Clin.Biochem_39_154
ESTHER : Boeck_2002_Ann.Clin.Biochem_39_154
PubMedSearch : Boeck_2002_Ann.Clin.Biochem_39_154
PubMedID: 11928765

Title : Substrate activation in acetylcholinesterase induced by low pH or mutation in the pi-cation subsite - Masson_2002_Biochim.Biophys.Acta_1594_313
Author(s) : Masson P , Schopfer LM , Bartels CF , Froment MT , Ribes F , Nachon F , Lockridge O
Ref : Biochimica & Biophysica Acta , 1594 :313 , 2002
Abstract : Masson_2002_Biochim.Biophys.Acta_1594_313
ESTHER : Masson_2002_Biochim.Biophys.Acta_1594_313
PubMedSearch : Masson_2002_Biochim.Biophys.Acta_1594_313
PubMedID: 11904227

Title : Engineering of a monomeric and low-glycosylated form of human butyrylcholinesterase: expression, purification, characterization and crystallization - Nachon_2002_Eur.J.Biochem_269_630
Author(s) : Nachon F , Nicolet Y , Viguie N , Masson P , Fontecilla-Camps JC , Lockridge O
Ref : European Journal of Biochemistry , 269 :630 , 2002
Abstract : Nachon_2002_Eur.J.Biochem_269_630
ESTHER : Nachon_2002_Eur.J.Biochem_269_630
PubMedSearch : Nachon_2002_Eur.J.Biochem_269_630
PubMedID: 11856322

Title : Cocaine metabolism accelerated by a re-engineered human butyrylcholinesterase - Sun_2002_J.Pharmacol.Exp.Ther_302_710
Author(s) : Sun H , Shen ML , Pang YP , Lockridge O , Brimijoin S
Ref : Journal of Pharmacology & Experimental Therapeutics , 302 :710 , 2002
Abstract : Sun_2002_J.Pharmacol.Exp.Ther_302_710
ESTHER : Sun_2002_J.Pharmacol.Exp.Ther_302_710
PubMedSearch : Sun_2002_J.Pharmacol.Exp.Ther_302_710
PubMedID: 12130735
Gene_locus related to this paper: human-BCHE

Title : Re-engineering butyrylcholinesterase as a cocaine hydrolase - Sun_2002_Mol.Pharmacol_62_220
Author(s) : Sun H , Pang YP , Lockridge O , Brimijoin S
Ref : Molecular Pharmacology , 62 :220 , 2002
Abstract : Sun_2002_Mol.Pharmacol_62_220
ESTHER : Sun_2002_Mol.Pharmacol_62_220
PubMedSearch : Sun_2002_Mol.Pharmacol_62_220
PubMedID: 12130672
Gene_locus related to this paper: human-BCHE

Title : Rescue of the acetylcholinesterase knockout mouse by feeding a liquid diet\; phenotype of the adult acetylcholinesterase deficient mouse - Duysen_2002_Brain.Res.Dev.Brain.Res_137_43
Author(s) : Duysen EG , Stribley JA , Fry DL , Hinrichs SH , Lockridge O
Ref : Brain Research Developmental Brain Research , 137 :43 , 2002
Abstract : Duysen_2002_Brain.Res.Dev.Brain.Res_137_43
ESTHER : Duysen_2002_Brain.Res.Dev.Brain.Res_137_43
PubMedSearch : Duysen_2002_Brain.Res.Dev.Brain.Res_137_43
PubMedID: 12128253

Title : Early weaning and culling eradicated Helicobacter hepaticus from an acetylcholinesterase knockout 129S6\/SvEvTac mouse colony - Duysen_2002_Comp.Med_52_461
Author(s) : Duysen EG , Fry DL , Lockridge O
Ref : Comp Med , 52 :461 , 2002
Abstract : Duysen_2002_Comp.Med_52_461
ESTHER : Duysen_2002_Comp.Med_52_461
PubMedSearch : Duysen_2002_Comp.Med_52_461
PubMedID: 12405641

Title : DNA sequence of butyrylcholinesterase from the rat: expression of the protein and characterization of the properties of rat butyrylcholinesterase - Boeck_2002_Biochem.Pharmacol_63_2101
Author(s) : Boeck AT , Schopfer LM , Lockridge O
Ref : Biochemical Pharmacology , 63 :2101 , 2002
Abstract : Boeck_2002_Biochem.Pharmacol_63_2101
ESTHER : Boeck_2002_Biochem.Pharmacol_63_2101
PubMedSearch : Boeck_2002_Biochem.Pharmacol_63_2101
PubMedID: 12110369
Gene_locus related to this paper: ratno-BCHE

Title : Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine - Mesulam_2002_Neurosci_110_627
Author(s) : Mesulam MM , Guillozet A , Shaw P , Levey AI , Duysen EG , Lockridge O , Levey A
Ref : Neuroscience , 110 :627 , 2002
Abstract : Mesulam_2002_Neurosci_110_627
ESTHER : Mesulam_2002_Neurosci_110_627
PubMedSearch : Mesulam_2002_Neurosci_110_627
PubMedID: 11934471

Title : Specificity of ethephon as a butyrylcholinesterase inhibitor and phosphorylating agent - Haux_2002_Chem.Res.Toxicol_15_1527
Author(s) : Haux JE , Lockridge O , Casida JE
Ref : Chemical Research in Toxicology , 15 :1527 , 2002
Abstract : Haux_2002_Chem.Res.Toxicol_15_1527
ESTHER : Haux_2002_Chem.Res.Toxicol_15_1527
PubMedSearch : Haux_2002_Chem.Res.Toxicol_15_1527
PubMedID: 12482234

Title : Wild-type and A328W mutant human butyrylcholinesterase tetramers expressed in Chinese hamster ovary cells have a 16-hour half-life in the circulation and protect mice from cocaine toxicity - Duysen_2002_J.Pharmacol.Exp.Ther_302_751
Author(s) : Duysen EG , Bartels CF , Lockridge O
Ref : Journal of Pharmacology & Experimental Therapeutics , 302 :751 , 2002
Abstract : Duysen_2002_J.Pharmacol.Exp.Ther_302_751
ESTHER : Duysen_2002_J.Pharmacol.Exp.Ther_302_751
PubMedSearch : Duysen_2002_J.Pharmacol.Exp.Ther_302_751
PubMedID: 12130740

Title : The active site of human paraoxonase (PON1) - Josse_2001_J.Appl.Toxicol_21 Suppl 1_S7
Author(s) : Josse D , Lockridge O , Xie W , Bartels CF , Schopfer LM , Masson P
Ref : J Appl Toxicol , 21 Suppl 1 :S7 , 2001
Abstract : Josse_2001_J.Appl.Toxicol_21 Suppl 1_S7
ESTHER : Josse_2001_J.Appl.Toxicol_21 Suppl 1_S7
PubMedSearch : Josse_2001_J.Appl.Toxicol_21 Suppl 1_S7
PubMedID: 11920913

Title : Predicted Michaelis-Menten complexes of cocaine-butyrylcholinesterase. Engineering effective butyrylcholinesterase mutants for cocaine detoxication. - Sun_2001_J.Biol.Chem_276_9330
Author(s) : Sun H , El Yazal J , Lockridge O , Schopfer LM , Brimijoin S , Pang YP
Ref : Journal of Biological Chemistry , 276 :9330 , 2001
Abstract : Sun_2001_J.Biol.Chem_276_9330
ESTHER : Sun_2001_J.Biol.Chem_276_9330
PubMedSearch : Sun_2001_J.Biol.Chem_276_9330
PubMedID: 11104759

Title : Effects of mutations of active site residues and amino acids interacting with the Omega loop on substrate activation of butyrylcholinesterase - Masson_2001_Biochim.Biophys.Acta_1544_166
Author(s) : Masson P , Xie W , Froment MT , Lockridge O
Ref : Biochimica & Biophysica Acta , 1544 :166 , 2001
Abstract : Masson_2001_Biochim.Biophys.Acta_1544_166
ESTHER : Masson_2001_Biochim.Biophys.Acta_1544_166
PubMedSearch : Masson_2001_Biochim.Biophys.Acta_1544_166
PubMedID: 11341926
Gene_locus related to this paper: human-BCHE

Title : Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to vx lethality - Duysen_2001_J.Pharmacol.Exp.Ther_299_528
Author(s) : Duysen EG , Li B , Xie W , Schopfer LM , Anderson RS , Broomfield CA , Lockridge O
Ref : Journal of Pharmacology & Experimental Therapeutics , 299 :528 , 2001
Abstract : Duysen_2001_J.Pharmacol.Exp.Ther_299_528
ESTHER : Duysen_2001_J.Pharmacol.Exp.Ther_299_528
PubMedSearch : Duysen_2001_J.Pharmacol.Exp.Ther_299_528
PubMedID: 11602663

Title : Postnatal developmental delay and supersensitivity to organophosphate in gene-targeted mice lacking acetylcholinesterase - Xie_2000_J.Pharmacol.Exp.Ther_293_896
Author(s) : Xie W , Stribley JA , Chatonnet A , Wilder PJ , Rizzino A , McComb RD , Taylor P , Hinrichs SH , Lockridge O
Ref : Journal of Pharmacology & Experimental Therapeutics , 293 :896 , 2000
Abstract : Xie_2000_J.Pharmacol.Exp.Ther_293_896
ESTHER : Xie_2000_J.Pharmacol.Exp.Ther_293_896
PubMedSearch : Xie_2000_J.Pharmacol.Exp.Ther_293_896
PubMedID: 10869390
Gene_locus related to this paper: mouse-ACHE

Title : Pesticides and susceptible populations: people with butyrylcholinesterase genetic variants may be at risk - Lockridge_2000_Neurotoxicol_21_113
Author(s) : Lockridge O , Masson P
Ref : Neurotoxicology , 21 :113 , 2000
Abstract : Lockridge_2000_Neurotoxicol_21_113
ESTHER : Lockridge_2000_Neurotoxicol_21_113
PubMedSearch : Lockridge_2000_Neurotoxicol_21_113
PubMedID: 10794391

Title : The butyrylcholinesterase K-variant shows similar cellular protein turnover and quaternary interaction to the wild-type enzyme - Altamirano_2000_J.Neurochem_74_869
Author(s) : Altamirano CV , Bartels CF , Lockridge O
Ref : Journal of Neurochemistry , 74 :869 , 2000
Abstract : Altamirano_2000_J.Neurochem_74_869
ESTHER : Altamirano_2000_J.Neurochem_74_869
PubMedSearch : Altamirano_2000_J.Neurochem_74_869
PubMedID: 10646540

Title : Abundant tissue butyrylcholinesterase and its possible function in the acetylcholinesterase knockout mouse - Li_2000_J.Neurochem_75_1320
Author(s) : Li B , Stribley JA , Ticu A , Xie W , Schopfer LM , Hammond P , Brimijoin S , Hinrichs SH , Lockridge O
Ref : Journal of Neurochemistry , 75 :1320 , 2000
Abstract : Li_2000_J.Neurochem_75_1320
ESTHER : Li_2000_J.Neurochem_75_1320
PubMedSearch : Li_2000_J.Neurochem_75_1320
PubMedID: 10936216

Title : Determination of the DNA sequences of acetylcholinesterase and butyrylcholinesterase from cat and demonstration of the existence of both in cat plasma - Bartels_2000_Biochem.Pharmacol_60_479
Author(s) : Bartels CF , Xie W , Miller-Lindholm AK , Schopfer LM , Lockridge O
Ref : Biochemical Pharmacology , 60 :479 , 2000
Abstract : Bartels_2000_Biochem.Pharmacol_60_479
ESTHER : Bartels_2000_Biochem.Pharmacol_60_479
PubMedSearch : Bartels_2000_Biochem.Pharmacol_60_479
PubMedID: 10874122
Gene_locus related to this paper: felca-ACHE , felca-BCHE , tiger-BCHE

Title : Interaction between the peripheral site residues of human butyrylcholinesterase, D70 and Y332, in binding and hydrolysis of substrates - Masson_1999_Biochim.Biophys.Acta_1433_281
Author(s) : Masson P , Xie W , Froment MT , Levitsky V , Fortier PL , Albaret C , Lockridge O
Ref : Biochimica & Biophysica Acta , 1433 :281 , 1999
Abstract : Masson_1999_Biochim.Biophys.Acta_1433_281
ESTHER : Masson_1999_Biochim.Biophys.Acta_1433_281
PubMedSearch : Masson_1999_Biochim.Biophys.Acta_1433_281
PubMedID: 10446378

Title : Human serum paraoxonase (PON1): identification of essential amino acid residues by group-selective labelling and site-directed mutagenesis - Josse_1999_Chem.Biol.Interact_119-120_71
Author(s) : Josse D , Xie W , Masson P , Lockridge O
Ref : Chemico-Biological Interactions , 119-120 :71 , 1999
Abstract : Josse_1999_Chem.Biol.Interact_119-120_71
ESTHER : Josse_1999_Chem.Biol.Interact_119-120_71
PubMedSearch : Josse_1999_Chem.Biol.Interact_119-120_71
PubMedID: 10421440

Title : Tryptophan residue(s) as major components of the human serum paraoxonase active site - Josse_1999_Chem.Biol.Interact_119-120_79
Author(s) : Josse D , Xie W , Masson P , Schopfer LM , Lockridge O
Ref : Chemico-Biological Interactions , 119-120 :79 , 1999
Abstract : Josse_1999_Chem.Biol.Interact_119-120_79
ESTHER : Josse_1999_Chem.Biol.Interact_119-120_79
PubMedSearch : Josse_1999_Chem.Biol.Interact_119-120_79
PubMedID: 10421441

Title : Identification of residues essential for human paraoxonase (PON1) arylesterase\/organophosphatase activities - Josse_1999_Biochemistry_38_2816
Author(s) : Josse D , Xie W , Renault F , Rochu D , Schopfer LM , Masson P , Lockridge O
Ref : Biochemistry , 38 :2816 , 1999
Abstract : Josse_1999_Biochemistry_38_2816
ESTHER : Josse_1999_Biochemistry_38_2816
PubMedSearch : Josse_1999_Biochemistry_38_2816
PubMedID: 10052953

Title : Knockout of one acetylcholinesterase allele in the mouse - Xie_1999_Chem.Biol.Interact_119-120_289
Author(s) : Xie W , Wilder PJ , Stribley J , Chatonnet A , Rizzino A , Taylor P , Hinrichs SH , Lockridge O
Ref : Chemico-Biological Interactions , 119-120 :289 , 1999
Abstract : Xie_1999_Chem.Biol.Interact_119-120_289
ESTHER : Xie_1999_Chem.Biol.Interact_119-120_289
PubMedSearch : Xie_1999_Chem.Biol.Interact_119-120_289
PubMedID: 10421464

Title : An improved cocaine hydrolase: the A328Y mutant of human butyrylcholinesterase is 4-fold more efficient - Xie_1999_Mol.Pharmacol_55_83
Author(s) : Xie W , Altamirano CV , Bartels CF , Speirs RJ , Cashman JR , Lockridge O
Ref : Molecular Pharmacology , 55 :83 , 1999
Abstract : Xie_1999_Mol.Pharmacol_55_83
ESTHER : Xie_1999_Mol.Pharmacol_55_83
PubMedSearch : Xie_1999_Mol.Pharmacol_55_83
PubMedID: 9882701

Title : Differences in active-site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase - Saxena_1999_Chem.Biol.Interact_119-120_61
Author(s) : Saxena A , Redman AM , Jiang X , Lockridge O , Doctor BP
Ref : Chemico-Biological Interactions , 119-120 :61 , 1999
Abstract : Saxena_1999_Chem.Biol.Interact_119-120_61
ESTHER : Saxena_1999_Chem.Biol.Interact_119-120_61
PubMedSearch : Saxena_1999_Chem.Biol.Interact_119-120_61
PubMedID: 10421439

Title : Polyol-induced activation by excess substrate of the D70G butyrylcholinesterase mutant - Levitsky_1999_Biochim.Biophys.Acta_1429_422
Author(s) : Levitsky V , Xie W , Froment MT , Lockridge O , Masson P
Ref : Biochimica & Biophysica Acta , 1429 :422 , 1999
Abstract : Levitsky_1999_Biochim.Biophys.Acta_1429_422
ESTHER : Levitsky_1999_Biochim.Biophys.Acta_1429_422
PubMedSearch : Levitsky_1999_Biochim.Biophys.Acta_1429_422
PubMedID: 9989227

Title : Association of tetramers of human butyrylcholinesterase is mediated by conserved aromatic residues of the carboxy terminus - Altamirano_1999_Chem.Biol.Interact_119-120_53
Author(s) : Altamirano CV , Lockridge O
Ref : Chemico-Biological Interactions , 119-120 :53 , 1999
Abstract : Altamirano_1999_Chem.Biol.Interact_119-120_53
ESTHER : Altamirano_1999_Chem.Biol.Interact_119-120_53
PubMedSearch : Altamirano_1999_Chem.Biol.Interact_119-120_53
PubMedID: 10421438

Title : Conserved aromatic residues of the C-terminus of human butyrylcholinesterase mediate the association of tetramers - Altamirano_1999_Biochemistry_38_13414
Author(s) : Altamirano CV , Lockridge O
Ref : Biochemistry , 38 :13414 , 1999
Abstract : Altamirano_1999_Biochemistry_38_13414
ESTHER : Altamirano_1999_Biochemistry_38_13414
PubMedSearch : Altamirano_1999_Biochemistry_38_13414
PubMedID: 10529218

Title : Protein engineering of a human enzyme that hydrolyzes V and G nerve agents: design, construction and characterization - Broomfield_1999_Chem.Biol.Interact_119-120_413
Author(s) : Broomfield CA , Lockridge O , Millard CB
Ref : Chemico-Biological Interactions , 119-120 :413 , 1999
Abstract : Broomfield_1999_Chem.Biol.Interact_119-120_413
ESTHER : Broomfield_1999_Chem.Biol.Interact_119-120_413
PubMedSearch : Broomfield_1999_Chem.Biol.Interact_119-120_413
PubMedID: 10421478

Title : Structural and hydration changes in the active site gorge of phosporhylated butyrylcholinesterase accompanying the aging process - Masson_1999_Chem.Biol.Interact_119-120_17
Author(s) : Masson P , Fortier PL , Albaret C , Clery C , Guerra P , Lockridge O
Ref : Chemico-Biological Interactions , 119-120 :17 , 1999
Abstract : Masson_1999_Chem.Biol.Interact_119-120_17
ESTHER : Masson_1999_Chem.Biol.Interact_119-120_17
PubMedSearch : Masson_1999_Chem.Biol.Interact_119-120_17
PubMedID: 10421435

Title : Reaction of Human Butyrylcholinesterase (BChE) H117 Enzymes with Carbamates -
Author(s) : Broomfield CA , Mills KV , Meier BM , Lockridge O , Millard CB
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :223 , 1998
PubMedID:

Title : Butyrylcholinesterase-catalysed hydrolysis of aspirin, a negatively charged ester, and aspirin-related neutral esters - Masson_1998_Biochim.Biophys.Acta_1387_41
Author(s) : Masson P , Froment MT , Fortier PL , Visicchio JE , Bartels CF , Lockridge O
Ref : Biochimica & Biophysica Acta , 1387 :41 , 1998
Abstract : Masson_1998_Biochim.Biophys.Acta_1387_41
ESTHER : Masson_1998_Biochim.Biophys.Acta_1387_41
PubMedSearch : Masson_1998_Biochim.Biophys.Acta_1387_41
PubMedID: 9748494

Title : pH Dependence of Dealkylation in Soman-Inhibited Cholinesterases and Their Mutants -
Author(s) : Viragh C , Saxena A , Frazier DS , Kovach IM , Lockridge O , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :247 , 1998
PubMedID:

Title : A Comparison of Blood Cholinesterase Activities, Pyridostigmine Inhibition of Red Cell Acetylcholinesterase, and Butyrylcholinesterase Phenotypes in Gulf War Veterans and Normal Controls -
Author(s) : Gentry MK , Powell S , Bitsko N , Bartels CF , Bartko J , Chung R , Lockridge O , Ribas J , Roy M , Malone J , Doctor BP
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :300 , 1998
PubMedID:

Title : Acetylcholinesterase and Butyrylcholinesterase of Cat -
Author(s) : Bartels CF , Xie W , Miller-Lindholm AK , Lockridge O
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :147 , 1998
PubMedID:

Title : Bert La Du ASPET Plenary Lecture: Bert N. La Du, a Summary of His Career to 1998 -
Author(s) : Lockridge O
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :1 , 1998
PubMedID:

Title : ACHE Knockout Mouse\; Cat AChE and Cat BChE Sequences\; Tetramers of BChE -
Author(s) : Lockridge O , Xie W , Chatonnet A , Taylor P , Bartels CF
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :41 , 1998
PubMedID:

Title : Organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase: synergy results in a somanase - Millard_1998_Biochemistry_37_237
Author(s) : Millard CB , Lockridge O , Broomfield CA
Ref : Biochemistry , 37 :237 , 1998
Abstract : Millard_1998_Biochemistry_37_237
ESTHER : Millard_1998_Biochemistry_37_237
PubMedSearch : Millard_1998_Biochemistry_37_237
PubMedID: 9425044
Gene_locus related to this paper: human-BCHE

Title : Enzymes hydrolyzing organophosphates as potential catalytic scavengers against organophosphate poisoning - Masson_1998_J.Physiol.Paris_92_357
Author(s) : Masson P , Josse D , Lockridge O , Viguie N , Taupin C , Buhler C
Ref : Journal de Physiologie (Paris) , 92 :357 , 1998
Abstract : Masson_1998_J.Physiol.Paris_92_357
ESTHER : Masson_1998_J.Physiol.Paris_92_357
PubMedSearch : Masson_1998_J.Physiol.Paris_92_357
PubMedID: 9789837

Title : Prolonged paralysis after a test dose of mivacurium in a patient with atypical serum cholinesterase -
Author(s) : Vanlinthout LE , Bartels CF , Lockridge O , Callens K , Booij LH
Ref : Anesthesia & Analgesia , 87 :1199 , 1998
PubMedID: 9806709

Title : The pH Dependence of Dealkylation in Soman-Inhibited Cholinesterases and Their Mutants: Further Evidence for a Push-Pull Mechanism - Saxena_1998_Biochemistry_37_15086
Author(s) : Saxena A , Viragh C , Frazier DS , Kovach IM , Maxwell DM , Lockridge O , Doctor BP
Ref : Biochemistry , 37 :15086 , 1998
Abstract : Saxena_1998_Biochemistry_37_15086
ESTHER : Saxena_1998_Biochemistry_37_15086
PubMedSearch : Saxena_1998_Biochemistry_37_15086
PubMedID: 9790671

Title : Structural Changes in the Active Site Gorge of Phosphylated Cholinesterase Accompanying the Aging Process -
Author(s) : Masson P , Clery C , Guerra P , Fortier PL , Albaret C , Lockridge O
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :419 , 1998
PubMedID:

Title : Resistance of butyrylcholinesterase to inactivation by ultrasound: effects of ultrasound on catalytic activity and subunit association - Froment_1998_Biochim.Biophys.Acta_1387_53
Author(s) : Froment MT , Lockridge O , Masson P
Ref : Biochimica & Biophysica Acta , 1387 :53 , 1998
Abstract : Froment_1998_Biochim.Biophys.Acta_1387_53
ESTHER : Froment_1998_Biochim.Biophys.Acta_1387_53
PubMedSearch : Froment_1998_Biochim.Biophys.Acta_1387_53
PubMedID: 9748500

Title : Association of Tetramers of Human Butyrylcholinesterase is Mediated by Conserved Aromatic Residues of the Carboxy Terminus -
Author(s) : Altamirano CV , Lockridge O
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :440 , 1998
PubMedID:

Title : Expression of Human Butyrylcholinesterase in Trichoplusia ni Insect Larvae -
Author(s) : Platteborze PL , Lockridge O , Broomfield CA
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :150 , 1998
PubMedID:

Title : Role of aspartate 70 and tryptophan 82 in binding of succinyldithiocholine to human butyrylcholinesterase - Masson_1997_Biochemistry_36_2266
Author(s) : Masson P , Legrand P , Bartels CF , Froment MT , Schopfer LM , Lockridge O
Ref : Biochemistry , 36 :2266 , 1997
Abstract : Masson_1997_Biochemistry_36_2266
ESTHER : Masson_1997_Biochemistry_36_2266
PubMedSearch : Masson_1997_Biochemistry_36_2266
PubMedID: 9047329

Title : Aging of di-isopropyl-phosphorylated human butyrylcholinesterase - Masson_1997_Biochem.J_327_601
Author(s) : Masson P , Fortier PL , Albaret C , Froment MT , Bartels CF , Lockridge O
Ref : Biochemical Journal , 327 ( Pt 2) :601 , 1997
Abstract : Masson_1997_Biochem.J_327_601
ESTHER : Masson_1997_Biochem.J_327_601
PubMedSearch : Masson_1997_Biochem.J_327_601
PubMedID: 9359435

Title : Tetramerization domain of human butyrylcholinesterase is at the C- terminus - Blong_1997_Biochem.J_327_747
Author(s) : Blong RM , Bedows E , Lockridge O
Ref : Biochemical Journal , 327 :747 , 1997
Abstract : Blong_1997_Biochem.J_327_747
ESTHER : Blong_1997_Biochem.J_327_747
PubMedSearch : Blong_1997_Biochem.J_327_747
PubMedID: 9581552

Title : Differences in active site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase - Saxena_1997_Biochemistry_36_14642
Author(s) : Saxena A , Redman AM , Jiang X , Lockridge O , Doctor BP
Ref : Biochemistry , 36 :14642 , 1997
Abstract : Saxena_1997_Biochemistry_36_14642
ESTHER : Saxena_1997_Biochemistry_36_14642
PubMedSearch : Saxena_1997_Biochemistry_36_14642
PubMedID: 9398183

Title : A single amino acid substitution, Gly117His, confers phosphotriesterase (organophosphorus acid anhydride hydrolase) activity on human butyrylcholinesterase - Lockridge_1997_Biochemistry_36_786
Author(s) : Lockridge O , Blong RM , Masson P , Froment MT , Millard CB , Broomfield CA
Ref : Biochemistry , 36 :786 , 1997
Abstract : Lockridge_1997_Biochemistry_36_786
ESTHER : Lockridge_1997_Biochemistry_36_786
PubMedSearch : Lockridge_1997_Biochemistry_36_786
PubMedID: 9020776

Title : Importance of aspartate-70 in organophosphate inhibition, oxime re-activation and aging of human butyrylcholinesterase - Masson_1997_Biochem.J_325_53
Author(s) : Masson P , Froment MT , Bartels CF , Lockridge O
Ref : Biochemical Journal , 325 :53 , 1997
Abstract : Masson_1997_Biochem.J_325_53
ESTHER : Masson_1997_Biochem.J_325_53
PubMedSearch : Masson_1997_Biochem.J_325_53
PubMedID: 9224629

Title : Asp7O in the peripheral anionic site of human butyrylcholinesterase - Masson_1996_Eur.J.Biochem_235_36
Author(s) : Masson P , Froment MT , Bartels CF , Lockridge O
Ref : European Journal of Biochemistry , 235 :36 , 1996
Abstract : Masson_1996_Eur.J.Biochem_235_36
ESTHER : Masson_1996_Eur.J.Biochem_235_36
PubMedSearch : Masson_1996_Eur.J.Biochem_235_36
PubMedID: 8631355

Title : Mutation of Human Butyrylcholinesterase Glycine 117 to Histidine Preserves Activity but Confers Resistance to Organophosphorus Inhibitors -
Author(s) : Broomfield CA , Millard CB , Lockridge O , Caviston TL
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :169 , 1995
PubMedID:

Title : Peripheral Anionic Site of Wild-Type and Mutant Human Butyrylcholinesterase -
Author(s) : Masson P , Froment MT , Bartels CF , Lockridge O
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :230 , 1995
PubMedID:

Title : Butyrylcholinesterase Transcription Start Site and Promoter -
Author(s) : Jbilo O , Toutant JP , Chatonnet A , Lockridge O
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :23 , 1995
PubMedID:

Title : Acetylcholinesterase Gene Sequence and Copy Number are Normal in Alzheimer's Disease Patients Treated with the Organophosphate Metrifonate -
Author(s) : Bartels CF , Moriearty PL , Becker RE , Mountjoy CP , Lockridge O
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :479 , 1995
PubMedID:

Title : Subunit Association and Stabilization of Butyrylcholinesterase (BChE) -
Author(s) : Blong RM , Masson P , Lockridge O
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :129 , 1995
PubMedID:

Title : Reconsideration of the catalytic center and mechanism of mammalian paraoxonase\/arylesterase - Sorenson_1995_Proc.Natl.Acad.Sci.U.S.A_92_7187
Author(s) : Sorenson RC , Primo-Parmo SL , Kuo CL , Adkins S , Lockridge O , La Du BN
Ref : Proc Natl Acad Sci U S A , 92 :7187 , 1995
Abstract : Sorenson_1995_Proc.Natl.Acad.Sci.U.S.A_92_7187
ESTHER : Sorenson_1995_Proc.Natl.Acad.Sci.U.S.A_92_7187
PubMedSearch : Sorenson_1995_Proc.Natl.Acad.Sci.U.S.A_92_7187
PubMedID: 7638166

Title : Design and expression of organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase - Millard_1995_Biochemistry_34_15925
Author(s) : Millard CB , Lockridge O , Broomfield CA
Ref : Biochemistry , 34 :15925 , 1995
Abstract : Millard_1995_Biochemistry_34_15925
ESTHER : Millard_1995_Biochemistry_34_15925
PubMedSearch : Millard_1995_Biochemistry_34_15925
PubMedID: 8519749

Title : Mutation His322Asn in human acetylcholinesterase does not alter electrophoretic and catalytic properties of the erythrocyte enzyme - Masson_1994_Blood_83_3003
Author(s) : Masson P , Froment MT , Sorenson RC , Bartels CF , Lockridge O
Ref : Blood , 83 :3003 , 1994
Abstract : Masson_1994_Blood_83_3003
ESTHER : Masson_1994_Blood_83_3003
PubMedSearch : Masson_1994_Blood_83_3003
PubMedID: 8180397

Title : Endogenous butyrylcholinesterase in SV40 transformed cell lines: COS-1, COS-7, MRC-5 SV40, and WI-38 VA13 - Kris_1994_In.Vitro.Cell.Dev.Biol.Animal_10_680
Author(s) : Kris M , Jbilo O , Bartels CF , Masson P , Rhode S , Lockridge O
Ref : In Vitro Cellular & Developmental Biology Animal , 10 :680 , 1994
Abstract : Kris_1994_In.Vitro.Cell.Dev.Biol.Animal_10_680
ESTHER : Kris_1994_In.Vitro.Cell.Dev.Biol.Animal_10_680
PubMedSearch : Kris_1994_In.Vitro.Cell.Dev.Biol.Animal_10_680
PubMedID: 7842168

Title : Bacterial expression and in vitro folding of the beta-subunit of human chorionic gonadotropin (hCG beta) and functional assembly of recombinant hCG beta with hCG alpha - Huth_1994_Endocrinology_135_911
Author(s) : Huth JR , Norton SE , Lockridge O , Shikone T , Hsueh AJ , Ruddon RW
Ref : Endocrinology , 135 :911 , 1994
Abstract : Huth_1994_Endocrinology_135_911
ESTHER : Huth_1994_Endocrinology_135_911
PubMedSearch : Huth_1994_Endocrinology_135_911
PubMedID: 8070386

Title : Tissue distribution of human acetylcholinesterase and butyrylcholinesterase messenger RNA - Jbilo_1994_Toxicon_32_1445
Author(s) : Jbilo O , Bartels CF , Chatonnet A , Toutant JP , Lockridge O
Ref : Toxicon , 32 :1445 , 1994
Abstract : Jbilo_1994_Toxicon_32_1445
ESTHER : Jbilo_1994_Toxicon_32_1445
PubMedSearch : Jbilo_1994_Toxicon_32_1445
PubMedID: 7886701

Title : Promoter and transcription start site of human and rabbit butyrylcholinesterase genes - Jbilo_1994_J.Biol.Chem_269_20829
Author(s) : Jbilo O , Toutant JP , Vatsis KP , Chatonnet A , Lockridge O
Ref : Journal of Biological Chemistry , 269 :20829 , 1994
Abstract : Jbilo_1994_J.Biol.Chem_269_20829
ESTHER : Jbilo_1994_J.Biol.Chem_269_20829
PubMedSearch : Jbilo_1994_J.Biol.Chem_269_20829
PubMedID: 8063698

Title : Mutation at codon 322 in the human acetylcholinesterase (ACHE) gene accounts for YT blood group polymorphism - Bartels_1993_Am.J.Hum.Genet_52_928
Author(s) : Bartels CF , Zelinski T , Lockridge O
Ref : American Journal of Human Genetics , 52 :928 , 1993
Abstract : Bartels_1993_Am.J.Hum.Genet_52_928
ESTHER : Bartels_1993_Am.J.Hum.Genet_52_928
PubMedSearch : Bartels_1993_Am.J.Hum.Genet_52_928
PubMedID: 8488842

Title : Recombinant human butyrylcholinesterase G390V, the fluoride-2 variant, expressed in Chinese hamster ovary cells, is a low affinity variant - Masson_1993_J.Biol.Chem_268_14329
Author(s) : Masson P , Adkins S , Gouet P , Lockridge O
Ref : Journal of Biological Chemistry , 268 :14329 , 1993
Abstract : Masson_1993_J.Biol.Chem_268_14329
ESTHER : Masson_1993_J.Biol.Chem_268_14329
PubMedSearch : Masson_1993_J.Biol.Chem_268_14329
PubMedID: 8314794

Title : Protein folding and assembly in vitro parallel intracellular folding and assembly. Catalysis of folding and assembly of the human chorionic gonadotropin alpha beta dimer by protein disulfide isomerase - Huth_1993_J.Biol.Chem_268_16472
Author(s) : Huth JR , Perini F , Lockridge O , Bedows E , Ruddon RW
Ref : Journal of Biological Chemistry , 268 :16472 , 1993
Abstract : Huth_1993_J.Biol.Chem_268_16472
ESTHER : Huth_1993_J.Biol.Chem_268_16472
PubMedSearch : Huth_1993_J.Biol.Chem_268_16472
PubMedID: 8344931

Title : Part 1: Genetic Variant of Human Acetylcholinesterase Part 2: SV-40 Transformed Cell Lines, for Example COS-1, but Not Parental Untransformed Cell Lines, Express Butyrylcholinesterase (BChE) -
Author(s) : Lockridge O , Bartels CF
Ref : In Multidisciplinary approaches to cholinesterase functions - Proceedings of Fourth International Meeting on Cholinesterases , (Shafferman, A. and Velan, B., Eds) Plenum Press, New York :53 , 1992
PubMedID:

Title : DNA mutation associated with the human butyrylcholinesterase K-variant and its linkage to the atypical variant mutation and other polymorphic sites - Bartels_1992_Am.J.Hum.Genet_50_1086
Author(s) : Bartels CF , Jensen FS , Lockridge O , van der Spek AF , Rubinstein HM , Lubrano T , La Du BN
Ref : American Journal of Human Genetics , 50 :1086 , 1992
Abstract : Bartels_1992_Am.J.Hum.Genet_50_1086
ESTHER : Bartels_1992_Am.J.Hum.Genet_50_1086
PubMedSearch : Bartels_1992_Am.J.Hum.Genet_50_1086
PubMedID: 1570838

Title : Identification of two different point mutations associated with the fluoride-resistant phenotype for human butyrylcholinesterase - Nogueira_1992_Am.J.Hum.Genet_51_821
Author(s) : Nogueira CP , Bartels CF , McGuire MC , Adkins S , Lubrano T , Rubinstein HM , Lightstone H , van der Spek AF , Lockridge O , La Du BN
Ref : American Journal of Human Genetics , 51 :821 , 1992
Abstract : Nogueira_1992_Am.J.Hum.Genet_51_821
ESTHER : Nogueira_1992_Am.J.Hum.Genet_51_821
PubMedSearch : Nogueira_1992_Am.J.Hum.Genet_51_821
PubMedID: 1415224

Title : The cloned butyrylcholinesterase (BCHE) gene maps to a single chromosome site, 3q26 - Allderdice_1991_Genomics_11_452
Author(s) : Allderdice PW , Gardner HA , Galutira D , Lockridge O , La Du BN , McAlpine PJ
Ref : Genomics , 11 :452 , 1991
Abstract : Allderdice_1991_Genomics_11_452
ESTHER : Allderdice_1991_Genomics_11_452
PubMedSearch : Allderdice_1991_Genomics_11_452
PubMedID: 1769657

Title : Use of the polymerase chain reaction for homology probing of butyrylcholinesterase from several vertebrates - Arpagaus_1991_J.Biol.Chem_266_6966
Author(s) : Arpagaus M , Chatonnet A , Masson P , Newton M , Vaughan TA , Bartels CF , Nogueira CP , La Du BN , Lockridge O
Ref : Journal of Biological Chemistry , 266 :6966 , 1991
Abstract : Arpagaus_1991_J.Biol.Chem_266_6966
ESTHER : Arpagaus_1991_J.Biol.Chem_266_6966
PubMedSearch : Arpagaus_1991_J.Biol.Chem_266_6966
PubMedID: 2016308
Gene_locus related to this paper: bovin-BCHE , canfa-BCHE , macmu-BCHE , pig-BCHE , sheep-BCHE

Title : Structure of Human Butyrylcholinesterase Gene and Expression in Mammalian Cells -
Author(s) : Lockridge O
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :168 , 1991
PubMedID:

Title : The cloning and expression of a gene encoding Old Yellow Enzyme from Saccharomyces carlsbergensis - Saito_1991_J.Biol.Chem_266_20720
Author(s) : Saito K , Thiele DJ , Davio M , Lockridge O , Massey V
Ref : Journal of Biological Chemistry , 266 :20720 , 1991
Abstract : Saito_1991_J.Biol.Chem_266_20720
ESTHER : Saito_1991_J.Biol.Chem_266_20720
PubMedSearch : Saito_1991_J.Biol.Chem_266_20720
PubMedID: 1939123

Title : Proposed nomenclature for human butyrylcholinesterase genetic variants identified by DNA sequencing - La Du_1991_Cell.Mol.Neurobiol_11_79
Author(s) : La Du BN , Bartels CF , Nogueira CP , Arpagaus M , Lockridge O
Ref : Cellular Molecular Neurobiology , 11 :79 , 1991
Abstract : La Du_1991_Cell.Mol.Neurobiol_11_79
ESTHER : La Du_1991_Cell.Mol.Neurobiol_11_79
PubMedSearch : La Du_1991_Cell.Mol.Neurobiol_11_79
PubMedID: 2013061

Title : Poster: Expression of the fluoride variant of human butyrylcholinesterase in chinese hamster ovary cells -
Author(s) : Adkins S , Vaughan TA , Bartels CF , La Du BN , Lockridge O
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :196 , 1991
PubMedID:

Title : Poster: Use of the polymerase chain reaction for homology probing of butyrylchoIinesterase (BCHE) in several animal species -
Author(s) : Arpagaus M , Vaughan TA , La Du BN , Lockridge O , Masson P , Chatonnet A , Newton M , Taylor P
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :194 , 1991
PubMedID:

Title : Poster: Nomenclature for human butyrylcholinesterase genetic variants identified by DNA sequencing -
Author(s) : Lockridge O , Bartels CF , Nogueira CP , Arpagaus M , Adkins S , La Du BN
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :193 , 1991
PubMedID:

Title : Poster: Practical consequences of having more than one mutation within the same butyrylcholinesterase gene -
Author(s) : La Du BN , Bartels CF , Lockridge O
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :192 , 1991
PubMedID:

Title : Poster: DNA Coding for the K polymorphism in linkage disequilibrium with atypical human butyrylcholinesterase complicates phenotyping -
Author(s) : Bartels CF , Lockridge O , La Du BN , van der Spek AF , Rubinstein HM , Lubrano T
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :191 , 1991
PubMedID:

Title : Poster: Identification of two different mutations associated with human butyrylcholinesterase fluoride resistance in serum -
Author(s) : Bartels CF , Nogueira CP , McGuire MC , Adkins S , Lockridge O , La Du BN , Rubinstein HM , Lubrano T , van der Spek AF , Lightstone H
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :190 , 1991
PubMedID:

Title : Poster: Search for alternative splicing of butyrylcholinesterase transcripts -
Author(s) : Jbilo O , Chatonnet A , Arpagaus M , Lockridge O
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :187 , 1991
PubMedID:

Title : The butyrylcholinesterase gene (BCHE) at 3q26.2 shows two RFLPs -
Author(s) : McAlpine PJ , Dixon M , Allderdice PW , Lockridge O , La Du BN
Ref : Nucleic Acids Research , 19 :5088 , 1991
PubMedID: 1717941

Title : Genetic variants of human serum cholinesterase influence metabolism of the muscle relaxant succinylcholine. - Lockridge_1990_Pharmacol.Ther_47_35
Author(s) : Lockridge O
Ref : Pharmacol Ther , 47 :35 , 1990
Abstract : Lockridge_1990_Pharmacol.Ther_47_35
ESTHER : Lockridge_1990_Pharmacol.Ther_47_35
PubMedSearch : Lockridge_1990_Pharmacol.Ther_47_35
PubMedID: 2195556
Gene_locus related to this paper: human-BCHE

Title : Evidence for a single butyrylcholinesterase gene in individuals carrying the C5 plasma cholinesterase variant (CHE2) - Masson_1990_FEBS.Lett_262_115
Author(s) : Masson P , Chatonnet A , Lockridge O
Ref : FEBS Letters , 262 :115 , 1990
Abstract : Masson_1990_FEBS.Lett_262_115
ESTHER : Masson_1990_FEBS.Lett_262_115
PubMedSearch : Masson_1990_FEBS.Lett_262_115
PubMedID: 2318303

Title : Structure of the gene for human butyrylcholinesterase. Evidence for a single copy - Arpagaus_1990_Biochemistry_29_124
Author(s) : Arpagaus M , Kott M , Vatsis KP , Bartels CF , La Du BN , Lockridge O
Ref : Biochemistry , 29 :124 , 1990
Abstract : Arpagaus_1990_Biochemistry_29_124
ESTHER : Arpagaus_1990_Biochemistry_29_124
PubMedSearch : Arpagaus_1990_Biochemistry_29_124
PubMedID: 2322535

Title : Phenotypic and molecular biological analysis of human butyrylcholinesterase variants - La Du_1990_Clin.Biochem_23_423
Author(s) : La Du BN , Bartels CF , Nogueira CP , Hajra A , Lightstone H , van der Spek AF , Lockridge O
Ref : Clinical Biochemistry , 23 :423 , 1990
Abstract : La Du_1990_Clin.Biochem_23_423
ESTHER : La Du_1990_Clin.Biochem_23_423
PubMedSearch : La Du_1990_Clin.Biochem_23_423
PubMedID: 2253336

Title : Identification of a frameshift mutation responsible for the silent phenotype of human serum cholinesterase, Gly 117 (GGT----GGAG) - Nogueira_1990_Am.J.Hum.Genet_46_934
Author(s) : Nogueira CP , McGuire MC , Graeser C , Bartels CF , Arpagaus M , van der Spek AF , Lightstone H , Lockridge O , La Du BN
Ref : American Journal of Human Genetics , 46 :934 , 1990
Abstract : Nogueira_1990_Am.J.Hum.Genet_46_934
ESTHER : Nogueira_1990_Am.J.Hum.Genet_46_934
PubMedSearch : Nogueira_1990_Am.J.Hum.Genet_46_934
PubMedID: 2339692

Title : Identification of the structural mutation responsible for the dibucaine-resistant (atypical) variant form of human serum cholinesterase - McGuire_1989_Proc.Natl.Acad.Sci.U.S.A_86_953
Author(s) : McGuire MC , Nogueira CP , Bartels CF , Lightstone H , Hajra A , van der Spek AF , Lockridge O , La Du BN
Ref : Proc Natl Acad Sci U S A , 86 :953 , 1989
Abstract : McGuire_1989_Proc.Natl.Acad.Sci.U.S.A_86_953
ESTHER : McGuire_1989_Proc.Natl.Acad.Sci.U.S.A_86_953
PubMedSearch : McGuire_1989_Proc.Natl.Acad.Sci.U.S.A_86_953
PubMedID: 2915989

Title : Comparison of butyrylcholinesterase and acetylcholinesterase. -
Author(s) : Chatonnet A , Lockridge O
Ref : Biochemical Journal , 260 :625 , 1989
PubMedID: 2669736

Title : Identification of a frameshift mutation (gly 117, GGT-to-GGAG) responsible for a silent phenotype of human serum cholinesterase. (Abstract) -
Author(s) : Nogueira CP , McGuire MC , Bartels CF , van der Spek AF , Lightstone H , Lockridge O , La Du BN
Ref : American Journal of Human Genetics , 45 (suppl.) :A210 , 1989
PubMedID:

Title : Structure of human serum cholinesterase. -
Author(s) : Lockridge O
Ref : Bioessays , 9 :125 , 1988
PubMedID: 3067729
Gene_locus related to this paper: human-BCHE

Title : Location of disulfide bonds within the sequence of human serum cholinesterase - Lockridge_1987_J.Biol.Chem_262_12945
Author(s) : Lockridge O , Adkins S , La Du BN
Ref : Journal of Biological Chemistry , 262 :12945 , 1987
Abstract : Lockridge_1987_J.Biol.Chem_262_12945
ESTHER : Lockridge_1987_J.Biol.Chem_262_12945
PubMedSearch : Lockridge_1987_J.Biol.Chem_262_12945
PubMedID: 3115973

Title : Brain cDNA clone for human cholinesterase - McTiernan_1987_Proc.Natl.Acad.Sci.U.S.A_84_6682
Author(s) : McTiernan C , Adkins S , Chatonnet A , Vaughan TA , Bartels CF , Kott M , Rosenberry TL , La Du BN , Lockridge O
Ref : Proceedings of the National Academy of Sciences of the United States of America , 84 :6682 , 1987
Abstract : McTiernan_1987_Proc.Natl.Acad.Sci.U.S.A_84_6682
ESTHER : McTiernan_1987_Proc.Natl.Acad.Sci.U.S.A_84_6682
PubMedSearch : McTiernan_1987_Proc.Natl.Acad.Sci.U.S.A_84_6682
PubMedID: 3477799
Gene_locus related to this paper: human-BCHE

Title : Complete amino acid sequence of human serum cholinesterase - Lockridge_1987_J.Biol.Chem_262_549
Author(s) : Lockridge O , Bartels CF , Vaughan TA , Wong CK , Norton SE , Johnson LL
Ref : Journal of Biological Chemistry , 262 :549 , 1987
Abstract : Lockridge_1987_J.Biol.Chem_262_549
ESTHER : Lockridge_1987_J.Biol.Chem_262_549
PubMedSearch : Lockridge_1987_J.Biol.Chem_262_549
PubMedID: 3542989
Gene_locus related to this paper: human-BCHE

Title : Amino acid sequence of the active site of human serum cholinesterase from usual, atypical, and atypical-silent genotypes - Lockridge_1986_Biochem.Genet_24_485
Author(s) : Lockridge O , La Du BN
Ref : Biochemical Genetics , 24 :485 , 1986
Abstract : Lockridge_1986_Biochem.Genet_24_485
ESTHER : Lockridge_1986_Biochem.Genet_24_485
PubMedSearch : Lockridge_1986_Biochem.Genet_24_485
PubMedID: 3741370

Title : Molecular biology of human serum cholinesterase. - La Du_1986_Fed.Proc_45_2965
Author(s) : La Du BN , Lockridge O
Ref : Federation Proceedings , 45 :2965 , 1986
Abstract : La Du_1986_Fed.Proc_45_2965
ESTHER : La Du_1986_Fed.Proc_45_2965
PubMedSearch : La Du_1986_Fed.Proc_45_2965
PubMedID: 3536596

Title : Amino acid composition and sequence of human serum cholinesterase: A progress report -
Author(s) : Lockridge O
Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter :5 , 1984
PubMedID:

Title : Immunological comparison of the usual and atypical human serum cholinesterase phenotypes - Eckerson_1983_Biochem.Genet_21_93
Author(s) : Eckerson HW , Oseroff A , Lockridge O , La Du BN
Ref : Biochemical Genetics , 21 :93 , 1983
Abstract : Eckerson_1983_Biochem.Genet_21_93
ESTHER : Eckerson_1983_Biochem.Genet_21_93
PubMedSearch : Eckerson_1983_Biochem.Genet_21_93
PubMedID: 6838493

Title : Loss of the interchain disulfide peptide and dissociation of the tetramer following limited proteolysis of native human serum cholinesterase -
Author(s) : Lockridge O , La Du BN
Ref : Journal of Biological Chemistry , 257 :12012 , 1982
PubMedID: 7118929

Title : Hydrolysis of methylprednisolone acetate by human serum cholinesterase -
Author(s) : Myers C , Lockridge O , La Du BN
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 10 :279 , 1982
PubMedID: 6125364

Title : Substance P hydrolysis by human serum cholinesterase - Lockridge_1982_J.Neurochem_39_106
Author(s) : Lockridge O
Ref : Journal of Neurochemistry , 39 :106 , 1982
Abstract : Lockridge_1982_J.Neurochem_39_106
ESTHER : Lockridge_1982_J.Neurochem_39_106
PubMedSearch : Lockridge_1982_J.Neurochem_39_106
PubMedID: 6177830

Title : Prediction of drug sensitivity in individuals with atypical serum cholinesterase based on in vitro biochemical studies - Valentino_1981_Biochem.Pharmacol_30_1643
Author(s) : Valentino RJ , Lockridge O , Eckerson HW , La Du BN
Ref : Biochemical Pharmacology , 30 :1643 , 1981
Abstract : Valentino_1981_Biochem.Pharmacol_30_1643
ESTHER : Valentino_1981_Biochem.Pharmacol_30_1643
PubMedSearch : Valentino_1981_Biochem.Pharmacol_30_1643
PubMedID: 7271851

Title : Hydrolysis of diacetylmorphine (heroin) by human serum cholinesterase - Lockridge_1980_J.Pharmacol.Exp.Ther_215_1
Author(s) : Lockridge O , Mottershaw-Jackson N , Eckerson HW , La Du BN
Ref : Journal of Pharmacology & Experimental Therapeutics , 215 :1 , 1980
Abstract : Lockridge_1980_J.Pharmacol.Exp.Ther_215_1
ESTHER : Lockridge_1980_J.Pharmacol.Exp.Ther_215_1
PubMedSearch : Lockridge_1980_J.Pharmacol.Exp.Ther_215_1
PubMedID: 7452476

Title : Prolonged apnea following trimethaphan and succinylcholine - Poulton_1979_Anesthesiology_50_54
Author(s) : Poulton TJ , James FMd , Lockridge O
Ref : Anesthesiology , 50 :54 , 1979
Abstract : Poulton_1979_Anesthesiology_50_54
ESTHER : Poulton_1979_Anesthesiology_50_54
PubMedSearch : Poulton_1979_Anesthesiology_50_54
PubMedID: 216287

Title : Interchain disulfide bonds and subunit organization in human serum cholinesterase -
Author(s) : Lockridge O , Eckerson HW , La Du BN
Ref : Journal of Biological Chemistry , 254 :8324 , 1979
PubMedID: 468826

Title : Comparison of atypical and usual human serum cholinesterase. Purification, number of active sites, substrate affinity, and turnover number - Lockridge_1978_J.Biol.Chem_253_361
Author(s) : Lockridge O , La Du BN
Ref : Journal of Biological Chemistry , 253 :361 , 1978
Abstract : Lockridge_1978_J.Biol.Chem_253_361
ESTHER : Lockridge_1978_J.Biol.Chem_253_361
PubMedSearch : Lockridge_1978_J.Biol.Chem_253_361
PubMedID: 618874