Gene Locus : human-ACHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Omega loop Alter both characteristic of active center and signal transmission from the PAS Velan_1996_FEBS.Lett_395_22
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Omega loop
Torpedo_number : 85
Kinetic Parameter : No kinetic parameter
News : No news
Comment :
p.N87A Asn87Ala (p.N118A Asn118Ala in primary sequence with 31 amino-acids signal peptide) Omega loop\;Alter both characteristic of active center and signal transmission from the PAS
Title : Structural modifications of the omega loop in human acetylcholinesterase - Velan_1996_FEBS.Lett_395_22 |
Author(s) : Velan B , Barak D , Ariel N , Leitner M , Bino T , Ordentlich A , Shafferman A |
Ref : FEBS Letters , 395 :22 , 1996 |
Abstract : |
PubMedSearch : Velan_1996_FEBS.Lett_395_22 |
PubMedID: 8849682 |