N87A_human-ACHE

General

Gene Locus : human-ACHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Omega loop Alter both characteristic of active center and signal transmission from the PAS Velan_1996_FEBS.Lett_395_22

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Omega loop

Torpedo_number : 85

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
p.N87A Asn87Ala (p.N118A Asn118Ala in primary sequence with 31 amino-acids signal peptide) Omega loop\;Alter both characteristic of active center and signal transmission from the PAS

References (1)

Title : Structural modifications of the omega loop in human acetylcholinesterase - Velan_1996_FEBS.Lett_395_22
Author(s) : Velan B , Barak D , Ariel N , Leitner M , Bino T , Ordentlich A , Shafferman A
Ref : FEBS Letters , 395 :22 , 1996
Abstract :
PubMedSearch : Velan_1996_FEBS.Lett_395_22
PubMedID: 8849682