R171C_human-CES1

General

Gene Locus : human-CES1

Mode of mutation : Natural mutant

Disease :

Summary : Natural mutant loss of function Wang_2017_Drug.Metab.Dispos_45_1149

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Natural mutation

Torpedo_number : 149

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
p.Arg171Cys Nucleotide change C619T rs201065375

References (2)

Title : Pharmacogenetic study of CES1 gene and enalapril efficacy - Hussain_2024_J.Appl.Genet__
Author(s) : Hussain M , Basheer S , Khalil A , Haider QUA , Saeed H , Faizan M
Ref : J Appl Genet , : , 2024
Abstract :
PubMedSearch : Hussain_2024_J.Appl.Genet__
PubMedID: 38261266
Gene_locus related to this paper: human-CES1

Title : A Comprehensive Functional Assessment of Carboxylesterase 1 Nonsynonymous Polymorphisms - Wang_2017_Drug.Metab.Dispos_45_1149
Author(s) : Wang X , Rida N , Shi J , Wu AH , Bleske BE , Zhu HJ
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 45 :1149 , 2017
Abstract :
PubMedSearch : Wang_2017_Drug.Metab.Dispos_45_1149
PubMedID: 28838926
Gene_locus related to this paper: human-CES1