| Title : Impact of carboxylesterase 1 genetic polymorphism on trandolapril activation in human liver and the pharmacokinetics and pharmacodynamics in healthy volunteers - Wang_2021_Clin.Transl.Sci__ |
| Author(s) : Wang X , Her L , Xiao J , Shi J , Wu AH , Bleske BE , Zhu HJ |
| Ref : Clin Transl Sci , : , 2021 |
| Abstract : |
| PubMedSearch : Wang_2021_Clin.Transl.Sci__ |
| PubMedID: 33660934 |
| Title : Plasma carboxylesterase 1 predicts methylphenidate exposure: a proof-of-concept study using plasma protein biomarker for hepatic drug metabolism - Shi_2021_Clin.Pharmacol.Ther__ |
| Author(s) : Shi J , Xiao J , Wang X , Jung SM , Bleske BE , Markowitz JS , Patrick KS , Zhu HJ |
| Ref : Clinical Pharmacology & Therapeutics , : , 2021 |
| Abstract : |
| PubMedSearch : Shi_2021_Clin.Pharmacol.Ther__ |
| PubMedID: 34743324 |
| Title : Effect of CES1 genetic variation on enalapril steady-state pharmacokinetics and pharmacodynamics in healthy subjects - Her_2021_Br.J.Clin.Pharmacol__ |
| Author(s) : Her LH , Wang X , Shi J , Choi HJ , Jung SM , Smith LS , Wu AH , Bleske BE , Zhu HJ |
| Ref : British Journal of Clinical Pharmacology , : , 2021 |
| Abstract : |
| PubMedSearch : Her_2021_Br.J.Clin.Pharmacol__ |
| PubMedID: 33963573 |
| Title : A Comprehensive Functional Assessment of Carboxylesterase 1 Nonsynonymous Polymorphisms - Wang_2017_Drug.Metab.Dispos_45_1149 |
| Author(s) : Wang X , Rida N , Shi J , Wu AH , Bleske BE , Zhu HJ |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 45 :1149 , 2017 |
| Abstract : |
| PubMedSearch : Wang_2017_Drug.Metab.Dispos_45_1149 |
| PubMedID: 28838926 |
| Gene_locus related to this paper: human-CES1 |
| Title : Dabigatran etexilate activation is affected by the CES1 genetic polymorphism G143E (rs71647871) and gender - Shi_2016_Biochem.Pharmacol_119_76 |
| Author(s) : Shi J , Wang X , Nguyen JH , Bleske BE , Liang Y , Liu L , Zhu HJ |
| Ref : Biochemical Pharmacology , 119 :76 , 2016 |
| Abstract : |
| PubMedSearch : Shi_2016_Biochem.Pharmacol_119_76 |
| PubMedID: 27614009 |
| Gene_locus related to this paper: human-CES1 |
| Title : Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation - Shi_2016_Drug.Metab.Dispos_44_554 |
| Author(s) : Shi J , Wang X , Nguyen J , Wu AH , Bleske BE , Zhu HJ |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 44 :554 , 2016 |
| Abstract : |
| PubMedSearch : Shi_2016_Drug.Metab.Dispos_44_554 |
| PubMedID: 26817948 |
| Gene_locus related to this paper: human-CES1 |