Gene Locus : mouse-ACHE, mouse-ACHE, mouse-ACHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Acyl pocket slightly enhances BTC hydrolysis Vellom_1993_Biochemistry_32_12
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Acyl specificity
Torpedo_number : 289
Kinetic Parameter : Acetylthiocholine_R296S_mouse-ACHE
News : No news
Comment :
p.Arg296Ser
| Title : Amino acid residues controlling acetylcholinesterase and butyrylcholinesterase specificity - Vellom_1993_Biochemistry_32_12 |
| Author(s) : Vellom DC , Radic Z , Li Y , Pickering NA , Camp S , Taylor P |
| Ref : Biochemistry , 32 :12 , 1993 |
| Abstract : |
| PubMedSearch : Vellom_1993_Biochemistry_32_12 |
| PubMedID: 8418833 |
| Title : Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors - Radic_1993_Biochemistry_32_12074 |
| Author(s) : Radic Z , Pickering NA , Vellom DC , Camp S , Taylor P |
| Ref : Biochemistry , 32 :12074 , 1993 |
| Abstract : |
| PubMedSearch : Radic_1993_Biochemistry_32_12074 |
| PubMedID: 8218285 |
| Title : Amino acid residues controlling acetylcholinesterase and butyrylcholinesterase specificity - Vellom_1993_Biochemistry_32_12 |
| Author(s) : Vellom DC , Radic Z , Li Y , Pickering NA , Camp S , Taylor P |
| Ref : Biochemistry , 32 :12 , 1993 |
| Abstract : |
| PubMedSearch : Vellom_1993_Biochemistry_32_12 |
| PubMedID: 8418833 |
| Title : Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors - Radic_1993_Biochemistry_32_12074 |
| Author(s) : Radic Z , Pickering NA , Vellom DC , Camp S , Taylor P |
| Ref : Biochemistry , 32 :12074 , 1993 |
| Abstract : |
| PubMedSearch : Radic_1993_Biochemistry_32_12074 |
| PubMedID: 8218285 |
| Title : Amino acid residues controlling acetylcholinesterase and butyrylcholinesterase specificity - Vellom_1993_Biochemistry_32_12 |
| Author(s) : Vellom DC , Radic Z , Li Y , Pickering NA , Camp S , Taylor P |
| Ref : Biochemistry , 32 :12 , 1993 |
| Abstract : |
| PubMedSearch : Vellom_1993_Biochemistry_32_12 |
| PubMedID: 8418833 |
| Title : Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors - Radic_1993_Biochemistry_32_12074 |
| Author(s) : Radic Z , Pickering NA , Vellom DC , Camp S , Taylor P |
| Ref : Biochemistry , 32 :12074 , 1993 |
| Abstract : |
| PubMedSearch : Radic_1993_Biochemistry_32_12074 |
| PubMedID: 8218285 |