R296S_mouse-ACHE

General

Gene Locus : mouse-ACHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Acyl pocket slightly enhances BTC hydrolysis Vellom_1993_Biochemistry_32_12

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Acyl specificity

Torpedo_number : 289

Kinetic Parameter : Acetylthiocholine_R296S_mouse-ACHE

News : No news

Comment :
p.Arg296Ser

References (2)

Title : Amino acid residues controlling acetylcholinesterase and butyrylcholinesterase specificity - Vellom_1993_Biochemistry_32_12
Author(s) : Vellom DC , Radic Z , Li Y , Pickering NA , Camp S , Taylor P
Ref : Biochemistry , 32 :12 , 1993
Abstract :
PubMedSearch : Vellom_1993_Biochemistry_32_12
PubMedID: 8418833

Title : Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors - Radic_1993_Biochemistry_32_12074
Author(s) : Radic Z , Pickering NA , Vellom DC , Camp S , Taylor P
Ref : Biochemistry , 32 :12074 , 1993
Abstract :
PubMedSearch : Radic_1993_Biochemistry_32_12074
PubMedID: 8218285