Gene Locus : human-CES1
Mode of mutation : Natural mutant
Disease :
Summary : Natural mutant Wang_2017_Drug.Metab.Dispos_45_1149 || Expression Clopidogrel metabolism is impaired Xiao_2017_Sci.Rep_7_7244
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Natural mutation
Torpedo_number : 55
Kinetic Parameter : No kinetic parameter
News : No news
Comment :
p.Ser75Asn Nucleotide change G332A rs2307240 || p.Ser75ASn rs2307240 C>T
| Title : Effect of carboxylesterase 1 S75N on clopidogrel therapy among acute coronary syndrome patients - Xiao_2017_Sci.Rep_7_7244 |
| Author(s) : Xiao FY , Luo JQ , Liu M , Chen BL , Cao S , Liu ZQ , Zhou HH , Zhou G , Zhang W |
| Ref : Sci Rep , 7 :7244 , 2017 |
| Abstract : |
| PubMedSearch : Xiao_2017_Sci.Rep_7_7244 |
| PubMedID: 28775293 |
| Gene_locus related to this paper: human-CES1 |
| Title : A Comprehensive Functional Assessment of Carboxylesterase 1 Nonsynonymous Polymorphisms - Wang_2017_Drug.Metab.Dispos_45_1149 |
| Author(s) : Wang X , Rida N , Shi J , Wu AH , Bleske BE , Zhu HJ |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 45 :1149 , 2017 |
| Abstract : |
| PubMedSearch : Wang_2017_Drug.Metab.Dispos_45_1149 |
| PubMedID: 28838926 |
| Gene_locus related to this paper: human-CES1 |