Y332D_human-BCHE

General

Gene Locus : human-BCHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Peripheral Anionic site interraction 70\/332 Masson_1999_Biochim.Biophys.Acta_1433_281

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Succinylthiocholine binding || Peripheral Anionic Site

Torpedo_number : 334

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
\/Y332D Tyr332Asp (p.Y360D Tyr360Asp in primary sequence with 28 amino-acids signal peptide) Peripheral Anionic site\;interraction 70(98)\/332(360)

References (1)

Title : Interaction between the peripheral site residues of human butyrylcholinesterase, D70 and Y332, in binding and hydrolysis of substrates - Masson_1999_Biochim.Biophys.Acta_1433_281
Author(s) : Masson P , Xie W , Froment MT , Levitsky V , Fortier PL , Albaret C , Lockridge O
Ref : Biochimica & Biophysica Acta , 1433 :281 , 1999
Abstract :
PubMedSearch : Masson_1999_Biochim.Biophys.Acta_1433_281
PubMedID: 10446378