Kinetic parameters

Tree Display

AceDB Schema

XML Display


Mutation Report for: A328D_human-BCHE

Mode of mutation|Natural mutant
Amino Acid change|A328D
Torpedo number|330
Comment|p.A328D Ala328Asp (p.A356T Ala356Thr in primary sequence with 28 amino-acids signal peptide) Found in a patient compound heterozygote with H variant by Gatke et al. rs770337031
Kinetic parameters|none

    Title: Understanding the non-catalytic behavior of human butyrylcholinesterase silent variants: comparison of wild-type enzyme, catalytically active Ala328Cys mutant, and silent Ala328Asp variant
    Lushchekina SV, Nemukhin AV, Varfolomeev SD, Masson P
    Ref: Chemico-Biological Interactions, 259:223, 2016 : PubMed


    Title: Two novel mutations in the BCHE gene in patients with prolonged duration of action of mivacurium or succinylcholine during anaesthesia
    Gatke MR, Bundgaard JR, Viby-Mogensen J
    Ref: Pharmacogenet Genomics, 17:995, 2007 : PubMed


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

Acknowledgements and disclaimer