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Mutation Report for: M303I_musdo-EST23aes07

Mode of mutation|Natural mutant
Amino Acid change|M303I
Torpedo number|287
Comment|p.Met303Ile n.G909A. For S250T W251S M303I L334L W378R S383T majority of female carried the homozygous susceptible allele in susceptible strain while males were primary heterozygous for these alleles. In resistant strains both male and females were homozygous for the mutation. T found also in some suceptible strains Zhang et al. 2010 Claudianos et al. 1999 and M found in Rutgers resistant strain
Kinetic parameters|none

    Title: Multiple mutations and overexpression of the MdaE7 carboxylesterase gene associated with male-linked malathion resistance in housefly, Musca domestica (Diptera: Muscidae)
    Zhang Y, Li J, Ma Z, Shan C, Gao X
    Ref: Sci Rep, 8:224, 2018 : PubMed


    Title: Quantitative and qualitative changes of the carboxylesterase associated with beta-cypermethrin resistance in the housefly, Musca domestica (Diptera: Muscidae)
    Zhang L, Shi J, Shi X, Liang P, Gao J, Gao X
    Ref: Comparative Biochemistry & Physiology B Biochem Mol Biol, 156:6, 2010 : PubMed


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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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