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Mutation Report for: W251S_musdo-EST23aes07

Mode of mutation|Natural mutant
Amino Acid change|W251S
Torpedo number|233
Comment|p.Trp251Ser n.G752C . increases OP hydrolase activity (E3-Rmal Malathion and dimethyl OP).
Kinetic parameters|none

    Title: Multiple Genetic Mutations Related to Insecticide Resistance are Detected in Field Kazakhstani House Flies (Muscidae: Diptera)
    Qu R, Zhu J, Li M, Jashenko R, Qiu X
    Ref: Journal of Medical Entomology, :, 2021 : PubMed


    Title: Multiple mutations and overexpression of the MdaE7 carboxylesterase gene associated with male-linked malathion resistance in housefly, Musca domestica (Diptera: Muscidae)
    Zhang Y, Li J, Ma Z, Shan C, Gao X
    Ref: Sci Rep, 8:224, 2018 : PubMed


    Title: Quantitative and qualitative changes of the carboxylesterase associated with beta-cypermethrin resistance in the housefly, Musca domestica (Diptera: Muscidae)
    Zhang L, Shi J, Shi X, Liang P, Gao J, Gao X
    Ref: Comparative Biochemistry & Physiology B Biochem Mol Biol, 156:6, 2010 : PubMed


    Title: Partial base sequence analysis of Md[alpha]E7 gene and ali-esterase enzyme activities in field collected populations of house fly (Musca domestica L.) from Mediterranean and Aegean Regions of Turkey
    Gacar F, Taskin V
    Ref: Pesticide Biochemistry and Physiology, 94:86, 2009 : PubMed


    Title: Determination of malathion and diazinon resistance by sequencing the Md alpha E7 gene from Guatemala, Colombia, Manhattan, and Thailand housefly (Musca domestica L.) strains
    Taskin V, Kence M, Gocmen B
    Ref: Genetika, 40:478, 2004 : PubMed


    Title: The genetic basis of malathion resistance in housefly (Musca domestica L.) strains from Turkey
    Taskin V, Kence M
    Ref: Genetika, 40:1475, 2004 : PubMed


    Title: The house fly aliesterase gene (MdalphaE7) is not associated with insecticide resistance or P450 expression in three strains of house fly
    Scott JG, Zhang L
    Ref: Insect Biochemistry & Molecular Biology, 33:139, 2003 : PubMed


    Title: The same amino acid substitution in orthologous esterases confers organophosphate resistance on the house fly and a blowfly
    Claudianos C, Russell RJ, Oakeshott JG
    Ref: Insect Biochemistry & Molecular Biology, 29:675, 1999 : PubMed


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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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