Title : Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv - Camus_2002_Microbiology_148_2967
Author(s) : Camus JC , Pryor MJ , Medigue C , Cole ST
Ref : Microbiology , 148 :2967 , 2002
Abstract :

Original genome annotations need to be regularly updated if the information they contain is to remain accurate and relevant. Here the complete re-annotation of the genome sequence of Mycobacterium tuberculosis strain H37Rv is presented almost 4 years after the first submission. Eighty-two new protein-coding sequences (CDS) have been included and 22 of these have a predicted function. The majority were identified by manual or automated re-analysis of the genome and most of them were shorter than the 100 codon cut-off used in the initial genome analysis. The functional classification of 643 CDS has been changed based principally on recent sequence comparisons and new experimental data from the literature. More than 300 gene names and over 1000 targeted citations have been added and the lengths of 60 genes have been modified. Presently, it is possible to assign a function to 2058 proteins (52% of the 3995 proteins predicted) and only 376 putative proteins share no homology with known proteins and thus could be unique to M. tuberculosis.

PubMedSearch : Camus_2002_Microbiology_148_2967
PubMedID: 12368430
Gene_locus related to this paper: myctu-d5yk66 , myctu-ephA , myctu-ephB , myctu-LPQP , myctu-p71654 , myctu-Rv0160c , myctu-RV0774C , myctu-Rv2485c , myctu-RV2672 , myctu-RV2695 , myctu-RV2765 , myctu-RV2800 , myctu-Rv2970c , myctu-Rv3084 , myctu-Rv3097c , myctu-RV3452

Related information

Gene_locus myctu-d5yk66    myctu-ephA    myctu-ephB    myctu-LPQP    myctu-p71654    myctu-Rv0160c    myctu-RV0774C    myctu-Rv2485c    myctu-RV2672    myctu-RV2695    myctu-RV2765    myctu-RV2800    myctu-Rv2970c    myctu-Rv3084    myctu-Rv3097c    myctu-RV3452

Citations formats

Camus JC, Pryor MJ, Medigue C, Cole ST (2002)
Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv
Microbiology 148 :2967

Camus JC, Pryor MJ, Medigue C, Cole ST (2002)
Microbiology 148 :2967