| Title : Acetylcholinesterase: The Hub for Neurodegenerative Diseases and Chemical Weapons Convention - Cavalcante_2020_Biomolecules_10_ |
| Author(s) : Cavalcante SFA , Simas ABC , Barcellos MC , de Oliveira VGM , Sousa RB , Cabral PAM , Kuca K , Franca TCC |
| Ref : Biomolecules , 10 : , 2020 |
|
Abstract :
This article describes acetylcholinesterase (AChE), an enzyme involved in parasympathetic neurotransmission, its activity, and how its inhibition can be pharmacologically useful for treating dementia, caused by Alzheimer's disease, or as a warfare method due to the action of nerve agents. The chemical concepts related to the irreversible inhibition of AChE, its reactivation, and aging are discussed, along with a relationship to the current international legislation on chemical weapons. |
| PubMedSearch : Cavalcante_2020_Biomolecules_10_ |
| PubMedID: 32155996 |
Cavalcante SFA, Simas ABC, Barcellos MC, de Oliveira VGM, Sousa RB, Cabral PAM, Kuca K, Franca TCC (2020)
Acetylcholinesterase: The Hub for Neurodegenerative Diseases and Chemical Weapons Convention
Biomolecules
10 :
Cavalcante SFA, Simas ABC, Barcellos MC, de Oliveira VGM, Sousa RB, Cabral PAM, Kuca K, Franca TCC (2020)
Biomolecules
10 :