Franca TCC

General

Full name : Costa Franca Tanos Celmar

First name : Tanos Celmar Costa

Mail : Military Institute of Engeneering IME\; Rua Lauro Muller 46\; apto 1201\; Botafogo -Rio de Janeiro RJ\; Rio de Janeiro 22290-160.

Zip Code :

City :

Country : Brazil

Email : tanos@ime.eb.br

Phone :

Fax :

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References (48)

Title : Pralidoxime-like reactivator with increased lipophilicity - Molecular modeling and in vitro study - Kuca_2023_Chem.Biol.Interact_14ChEPon_110734
Author(s) : Kuca K , Valle da Silva JA , Nepovimova E , Pham NL , Wu W , Valis M , Wu Q , Franca TCC
Ref : Chemico-Biological Interactions , :110734 , 2023
PubMedID: 37788753

Title : Molecular modeling of Mannich phenols as reactivators of human acetylcholinesterase inhibited by A-series nerve agents - Vieira_2023_Chem.Biol.Interact_14ChEPon_110622
Author(s) : Vieira LA , Almeida J , De Koning MC , LaPlante SR , Borges I , Franca TCC
Ref : Chemico-Biological Interactions , :110622 , 2023
PubMedID: 37442286

Title : In vitro comparison of the acetylcholinesterase inhibition caused by V- and A-series nerve agents' surrogates - Kitagawa_2023_Chem.Biol.Interact_14ChEPon_110678
Author(s) : Kitagawa DAS , Dos Santos MC , Kuca K , Franca TCC , Cavalcante SFA
Ref : Chemico-Biological Interactions , 383 :110678 , 2023
PubMedID: 37595776

Title : Applications of the Near Attack Conformation (NAC) approach in the search for Acetylcholinesterase reactivators - Franca_2023_Chem.Biol.Interact_14ChEPon_382_110619
Author(s) : Franca TCC , Valle da Silva JA , Dos Santos MC , Cavalcante SFA , Kuca K
Ref : Chemico-Biological Interactions , 382 :110619 , 2023
PubMedID: 37406983

Title : N-substituted arylhydroxamic acids as acetylcholinesterase reactivators - Bondar_2022_Chem.Biol.Interact__110078
Author(s) : Bondar D , Kapitanov I , Pulkrabkova L , Soukup O , Jun D , Diniz FB , Franca TCC , Kuca K , Karpichev Y
Ref : Chemico-Biological Interactions , :110078 , 2022
PubMedID: 35940282

Title : Are the current commercially available oximes capable of reactivating acetylcholinesterase inhibited by the nerve agents of the A-series? - Santos_2022_Arch.Toxicol__
Author(s) : Santos MC , Botelho FD , Goncalves AS , Kitagawa DAS , Borges CVN , Carvalho-Silva T , Bernardo LB , Ferreira CN , Rodrigues RB , Ferreira Neto DC , Nepovimova E , Kuca K , LaPlante SR , Lima ALS , Franca TCC , Cavalcante SFA
Ref : Archives of Toxicology , : , 2022
PubMedID: 35666269

Title : Theoretical assessment of the performances of commercial oximes on the reactivation of acetylcholinesterase inhibited by the nerve agent A-242 (novichok) - Santos_2022_Food.Chem.Toxicol__113084
Author(s) : Santos MC , Botelho FD , Goncalves AS , Kuca K , Nepovimova E , Cavalcante SFA , Lima ALS , Franca TCC
Ref : Food & Chemical Toxicology , :113084 , 2022
PubMedID: 35489467

Title : Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators - Kitagawa_2021_J.Enzyme.Inhib.Med.Chem_36_1370
Author(s) : Kitagawa DAS , Rodrigues RB , Silva TN , Dos Santos WV , da Rocha VCV , de Almeida JSFD , Bernardo LB , Carvalho-Silva T , Ferreira CN , da Silva AAT , Simas ABC , Nepovimova E , Kuca K , Franca TCC , Cavalcante SFA
Ref : J Enzyme Inhib Med Chem , 36 :1370 , 2021
PubMedID: 34148470

Title : Review about structure and evaluation of reactivators of Acetylcholinesterase inhibited with neurotoxic organophosphorus compounds - Figueroa-Villar_2020_Curr.Med.Chem__
Author(s) : Figueroa-Villar JD , Petronilho EC , Kuca K , Franca TCC
Ref : Curr Med Chem , : , 2020
PubMedID: 32334495

Title : Design, synthesis, molecular modeling and neuroprotective effects of a new framework of cholinesterase inhibitors for Alzheimer's disease - Zanon_2020_J.Biomol.Struct.Dyn__1
Author(s) : Zanon VS , Lima JA , Amaral RF , Lima FRS , Kitagawa DAS , Franca TCC , Vargas MD
Ref : J Biomol Struct Dyn , :1 , 2020
PubMedID: 32715924

Title : Molecular Modeling Study of Uncharged Oximes Compared to HI-6 and 2-PAM Inside Human AChE Sarin and VX Conjugates - Souza_2020_ACS.Omega_5_4490
Author(s) : Souza FR , Rodrigues Garcia D , Cuya T , Pimentel AS , Goncalves ADS , Alencastro RB , Franca TCC
Ref : ACS Omega , 5 :4490 , 2020
PubMedID: 32175496

Title : Ligand-Based Virtual Screening, Molecular Docking, Molecular Dynamics, and MM-PBSA Calculations towards the Identification of Potential Novel Ricin Inhibitors - Botelho_2020_Toxins.(Basel)_12_
Author(s) : Botelho FD , Dos Santos MC , Goncalves ADS , Kuca K , Valis M , LaPlante SR , Franca TCC , de Almeida J
Ref : Toxins (Basel) , 12 : , 2020
PubMedID: 33256167

Title : Reactivation of VX-Inhibited Human Acetylcholinesterase by Deprotonated Pralidoxime. A Complementary Quantum Mechanical Study - da Silva_2020_Biomolecules_10_
Author(s) : da Silva JAV , Pereira AF , LaPlante SR , Kuca K , Ramalho TC , Franca TCC
Ref : Biomolecules , 10 : , 2020
PubMedID: 32012780

Title : Acetylcholinesterase: The Hub for Neurodegenerative Diseases and Chemical Weapons Convention - Cavalcante_2020_Biomolecules_10_
Author(s) : Cavalcante SFA , Simas ABC , Barcellos MC , de Oliveira VGM , Sousa RB , Cabral PAM , Kuca K , Franca TCC
Ref : Biomolecules , 10 : , 2020
PubMedID: 32155996

Title : A molecular modeling study of components of the ginger (Zingiber officinale) extract inside human butyrylcholinesterase: implications for Alzheimer disease -
Author(s) : Cuya T , Franca TCC
Ref : J Biomol Struct Dyn , :1 , 2019
PubMedID: 31304886

Title : Novichoks: The Dangerous Fourth Generation of Chemical Weapons - Franca_2019_Int.J.Mol.Sci_20_
Author(s) : Franca TCC , Kitagawa DAS , Cavalcante SFA , da Silva JAV , Nepovimova E , Kuca K
Ref : Int J Mol Sci , 20 : , 2019
PubMedID: 30862059

Title : In Vitro Evaluation of Neutral Aryloximes as Reactivators for Electrophorus eel Acetylcholinesterase Inhibited by Paraoxon - Kitagawa_2019_Biomolecules_9_
Author(s) : Kitagawa DAS , Cavalcante SFA , de Paula RL , Rodrigues RB , Bernardo LB , da Silva MCJ , da Silva TN , Dos Santos WV , Granjeiro JM , de Almeida JSFD , Barcellos MC , de ACAB , Franca TCC , Kuca K , Simas ABC
Ref : Biomolecules , 9 : , 2019
PubMedID: 31597234

Title : Synthesis of New Quinoline-Piperonal Hybrids as Potential Drugs against Alzheimer's Disease - de Oliveira_2019_Int.J.Mol.Sci_20_
Author(s) : de Oliveira CBJ , Neto DCF , de Almeida JSFD , Lima JA , Kuca K , Franca TCC , Figueroa-Villar JD
Ref : Int J Mol Sci , 20 : , 2019
PubMedID: 31416113

Title : Synthesis and in vitro evaluation of neutral aryloximes as reactivators of Electrophorus eel acetylcholinesterase inhibited by NEMP, a VX surrogate - Cavalcante_2019_Chem.Biol.Interact_13ChEPon_309_108682
Author(s) : Cavalcante SFA , Kitagawa DAS , Rodrigues RB , Bernardo LB , da Silva TN , Dos Santos WV , Correa ABA , de Almeida JSFD , Franca TCC , Kuca K , Simas ABC
Ref : Chemico-Biological Interactions , 309 :108682 , 2019
PubMedID: 31163137

Title : Biodegradation of Organophosphorus Compounds Predicted by Enzymatic Process Using Molecular Modelling and Observed in Soil Samples Through Analytical Techniques and Microbiological Analysis: A Comparison - Cardozo_2019_Molecules_25_
Author(s) : Cardozo M , de Almeida J , Cavalcante SFA , Salgado JRS , Goncalves AS , Franca TCC , Kuca K , Bizzo HR
Ref : Molecules , 25 : , 2019
PubMedID: 31878010

Title : Chemical Composition and Biological Activities of Metania and Drulia (Metaniidae) Freshwater Sponges from Amazonia - Manco_2019_Chem.Biodivers_16_e1900318
Author(s) : Manco da Costa Bolson GC , Bezerra de Barros I , Volkmer-Ribeiro C , Alencar Lima J , Franca TCC , Santos I , Puccinelli Orlandi P , Florencio da Veiga-Junior V
Ref : Chem Biodivers , 16 :e1900318 , 2019
PubMedID: 31364803

Title : Interactions of human butyrylcholinesterase with phenylvalerate and acetylthiocholine as substrates and inhibitors: kinetic and molecular modeling approaches - Estevez_2019_Arch.Toxicol_93_1281
Author(s) : Estevez J , Rodrigues de Souza F , Romo M , Mangas I , Franca TCC , Vilanova E
Ref : Archives of Toxicology , 93 :1281 , 2019
PubMedID: 30877329

Title : Molecular modeling studies on the interactions of 7-methoxytacrine-4-pyridinealdoxime, 4-PA, 2-PAM, and obidoxime with VX-inhibited human acetylcholinesterase: a near attack conformation approach - da Silva_2019_J.Enzyme.Inhib.Med.Chem_34_1018
Author(s) : da Silva JAV , Nepovimova E , Ramalho TC , Kuca K , Franca TCC
Ref : J Enzyme Inhib Med Chem , 34 :1018 , 2019
PubMedID: 31074292

Title : Molecular modelling studies on the interactions of 7-methoxytacrine-4-pyridinealdoxime with VX-inhibited human acetylcholinesterase. A near attack approach to assess different spacer-lengths - da Silva_2019_Chem.Biol.Interact_13ChEPon_307_195
Author(s) : da Silva JAV , Nepovimova E , Ramalho TC , Kuca K , Franca TCC
Ref : Chemico-Biological Interactions , 307 :195 , 2019
PubMedID: 31121152

Title : Slight difference in the isomeric oximes K206 and K203 makes huge difference for the reactivation of organophosphorus-inhibited AChE: Theoretical and experimental aspects - Polisel_2019_Chem.Biol.Interact_13ChEPon_309_108671
Author(s) : Polisel DA , de Castro AA , Mancini DT , da Cunha EFF , Franca TCC , Ramalho TC , Kuca K
Ref : Chemico-Biological Interactions , 309 :108671 , 2019
PubMedID: 31207225

Title : Surface screening, molecular modeling and in vitro studies on the interactions of aflatoxin M1 and human enzymes acetyl- and butyrylcholinesterase - de Almeida_2019_Chem.Biol.Interact_13ChEPon_308_113
Author(s) : de Almeida JSFD , Cavalcante SFA , Dolezal R , Kuca K , Musilek K , Jun D , Franca TCC
Ref : Chemico-Biological Interactions , 308 :113 , 2019
PubMedID: 31100275

Title : A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase - Kuca_2018_BMC.Pharmacol.Toxicol_19_8
Author(s) : Kuca K , Musilek K , Jun D , Karasova JZ , Nepovimova E , Soukup O , Hrabinova M , Mikler J , Franca TCC , da Cunha EFF , de Castro AA , Valis M , Ramalho TC
Ref : BMC Pharmacol Toxicol , 19 :8 , 2018
PubMedID: 29467029

Title : Synthesis, Biological Evaluation, and Docking Studies of Novel Bisquaternary Aldoxime Reactivators on Acetylcholinesterase and Butyrylcholinesterase Inhibited by Paraoxon - Kuca_2018_Molecules_23_
Author(s) : Kuca K , Jun D , Junova L , Musilek K , Hrabinova M , da Silva JAV , Ramalho TC , Valko M , Wu Q , Nepovimova E , Franca TCC
Ref : Molecules , 23 : , 2018
PubMedID: 29735900

Title : In-vitro evaluation studies of 7-chloro-4-aminoquinoline Schiff bases and their copper complexes as cholinesterase inhibitors - Zanon_2018_J.Inorg.Biochem_191_183
Author(s) : Zanon VS , Lima JA , Cuya T , Lima FRS , da Fonseca ACC , Gomez JG , Ribeiro RR , Franca TCC , Vargas MD
Ref : J Inorg Biochem , 191 :183 , 2018
PubMedID: 30530179

Title : Molecular Modeling and In Vitro Studies of a Neutral Oxime as a Potential Reactivator for Acetylcholinesterase Inhibited by Paraoxon - de Paula_2018_Molecules_23_
Author(s) : de Paula RL , de Almeida JSFD , Cavalcante SFA , Goncalves AS , Simas ABC , Franca TCC , Valis M , Kuca K , Nepovimova E , Granjeiro JM
Ref : Molecules , 23 : , 2018
PubMedID: 30424582

Title : Molecular modeling studies on the interactions of aflatoxin B1 and its metabolites with the peripheral anionic site (PAS) of human acetylcholinesterase - de Almeida_2018_J.Biomol.Struct.Dyn__1
Author(s) : de Almeida JSFD , Cavalcante SFA , Dolezal R , Kuca K , Musilek K , Jun D , Franca TCC
Ref : J Biomol Struct Dyn , :1 , 2018
PubMedID: 29749305

Title : Molecular Modeling Studies on the Interactions of Aflatoxin B1 and Its Metabolites with Human Acetylcholinesterase. Part II: Interactions with the Catalytic Anionic Site (CAS) - de Almeida_2018_Toxins.(Basel)_10_
Author(s) : de Almeida JSFD , Dolezal R , Krejcar O , Kuca K , Musilek K , Jun D , Franca TCC
Ref : Toxins (Basel) , 10 : , 2018
PubMedID: 30257474

Title : Quantification through TLC-densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves - Affonso_2018_Biomed.Chromatogr_32_
Author(s) : Affonso RS , Lima JA , Lessa BM , Caetano JVO , Obara MT , Nobrega AB , Nepovimova E , Musilek K , Kuca K , Slana G , Franca TCC
Ref : Biomedical Chromatography , 32 : , 2018
PubMedID: 28913959

Title : New semicarbazones as gorge-spanning ligands of acetylcholinesterase and potential new drugs against Alzheimer's disease: Synthesis, molecular modeling, NMR and biological evaluation - Neto_2017_J.Biomol.Struct.Dyn__1
Author(s) : Neto DCF , Lima JA , de Almeida JSFD , Franca TCC , Nascimento CJD , Figueroa Villar JD
Ref : J Biomol Struct Dyn , :1 , 2017
PubMedID: 29198175

Title : The role of the oximes HI-6 and HS-6 inside human acetylcholinesterase inhibited with nerve agents: A computational study - Cuya_2017_J.Biomol.Struct.Dyn__1
Author(s) : Cuya T , Goncalves ADS , da Silva JAV , Ramalho TC , Kuca K , Franca TCC
Ref : J Biomol Struct Dyn , :1 , 2017
PubMedID: 29019446

Title : A molecular dynamics study of components of the ginger (Zingiber officinale) extract inside human acetylcholinesterase: Implications for Alzheimer disease - Cuya_2017_J.Biomol.Struct.Dyn__2
Author(s) : Cuya T , Baptista L , Franca TCC
Ref : J Biomol Struct Dyn , :1 , 2017
PubMedID: 29096599

Title : Behavior of uncharged oximes compared to HI6 and 2-PAM in the human AChE-Tabun conjugate: A molecular modeling approach - de Souza_2017_J.Biomol.Struct.Dyn__1
Author(s) : de Souza FR , Garcia DR , Guizado TC , Kuca K , de Alencastro RB , Franca TCC
Ref : J Biomol Struct Dyn , :1 , 2017
PubMedID: 28446076

Title : New insights on molecular interactions of organophosphorus pesticides with esterases - Mangas_2017_Toxicology_376_30
Author(s) : Mangas I , Estevez J , Vilanova E , Franca TCC
Ref : Toxicology , 376 :30 , 2017
PubMedID: 27311923

Title : Docking and molecular dynamics studies of peripheral site ligand-oximes as reactivators of sarin-inhibited human acetylcholinesterase - de Almeida_2016_J.Biomol.Struct.Dyn_34_2632
Author(s) : de Almeida JSFD , Guizado TR , Guimaraes AP , Ramalho TC , Goncalves AS , De Koning MC , Franca TCC
Ref : J Biomol Struct Dyn , 34 :2632 , 2016
PubMedID: 26612005

Title : Mechanistic studies of new oximes reactivators of human butyrylcholinesterase inhibited by cyclosarin and sarin - de Lima_2016_J.Biomol.Struct.Dyn__1
Author(s) : de Lima WE , Francisco A , da Cunha EFF , Radic Z , Taylor P , Franca TCC , Ramalho TC
Ref : J Biomol Struct Dyn , :1 , 2016
PubMedID: 27125569

Title : Resolving pathways of interaction of mipafox and a sarin analog with human acetylcholinesterase by kinetics, mass spectrometry and molecular modeling approaches - Mangas_2016_Arch.Toxicol_90_603
Author(s) : Mangas I , Taylor P , Vilanova E , Estevez J , Franca TCC , Komives E , Radic Z
Ref : Archives of Toxicology , 90 :603 , 2016
PubMedID: 25743373

Title : Computational Enzymology and Organophosphorus Degrading Enzymes: Promising Approaches Toward Remediation Technologies of Warfare Agents and Pesticides - Ramalho_2016_Curr.Med.Chem_23_1041
Author(s) : Ramalho TC , de Castro AA , Silva DR , Silva MC , Franca TCC , Bennion BJ , Kuca K
Ref : Curr Med Chem , 23 :1041 , 2016
PubMedID: 26898655

Title : Computational studies of acetylcholinesterase complexed with fullerene derivatives: A new insight for Alzheimer disease treatment - Goncalves_2015_J.Biomol.Struct.Dyn__1
Author(s) : Goncalves AD , Franca TCC , Vital de Oliveira O
Ref : J Biomol Struct Dyn , :1 , 2015
PubMedID: 26219766

Title : Molecular modeling and in vitro reactivation study between the oxime BI-6 and acetylcholinesterase inhibited by different nerve agents - Giacoppo_2015_J.Biomol.Struct.Dyn_33_2048
Author(s) : Giacoppo JO , Franca TCC , Kuca K , da Cunha EFF , Abagyan R , Mancini DT , Ramalho TC
Ref : J Biomol Struct Dyn , 33 :2048 , 2015
PubMedID: 25407587

Title : Reactivation steps by 2-PAM of tabun-inhibited human acetylcholinesterase: reducing the computational cost in hybrid QM\/MM methods - da Silva Goncalves_2014_J.Biomol.Struct.Dyn_32_301
Author(s) : da Silva Goncalves A , Franca TCC , Caetano MS , Ramalho TC
Ref : J Biomol Struct Dyn , 32 :301 , 2014
PubMedID: 23527625

Title : Chemical warfare: perspectives on reactivating the enzyme acetylcholinesterase inhibited by organophosphates - Giacoppo_2014_Mil.Med.Sci.Lett_83_165
Author(s) : Giacoppo JO , de Lima WE , Kuca K , da Cunha EFF , Franca TCC , Ramalho TC
Ref : Military Medical Science Letters , 83 :165 , 2014
PubMedID:

Title : First principles calculations of thermodynamics and kinetic parameters and molecular dynamics simulations of acetylcholinesterase reactivators: can mouse data provide new insights into humans? - Matos_2012_J.Biomol.Struct.Dyn_30_546
Author(s) : Matos KS , da Cunha EFF , da Silva Goncalves A , Wilter A , Kuca K , Franca TCC , Ramalho TC
Ref : J Biomol Struct Dyn , 30 :546 , 2012
PubMedID: 22731788

Title : Development of new acetylcholinesterase reactivators: molecular modeling versus in vitro data - Ramalho_2010_Chem.Biol.Interact_185_73
Author(s) : Ramalho TC , Franca TCC , Renno MN , Guimaraes AP , da Cunha EFF , Kuca K
Ref : Chemico-Biological Interactions , 185 :73 , 2010
PubMedID: 20188081