| Title : Isolation and identification of a novel cDNA that encodes human yrdC protein - Chen_2003_J.Hum.Genet_48_164 |
| Author(s) : Chen J , Ji C , Gu S , Zhao E , Dai J , Huang L , Qian J , Ying K , Xie Y , Mao Y |
| Ref : J Hum Genet , 48 :164 , 2003 |
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Abstract :
In the course of detecting the interaction protein of RBBP10 by yeast two-hybridization, we isolated a novel cDNA that encodes a putative human protein with yrdC domain. It is named human yrdC protein. Because the cDNA contains an open reading fragment (ORF) without a 5' in- frame stop codon, 5' RACE and 3' RACE were proceeded to produce the full-length cDNA. An 1825 bp cDNA was isolated from human placenta, which encodes a putative protein of 279 amino acids. The protein contains a sua5-yciO-yrdC domain. Blast analysis against the human genome database of Genbank revealed that the gene contains five exons, and assigned the gene to human chromosome 1p34.2. A transcript about 2.5 kb is ubiquitously expressed in human tissues. The gene is highly conserved during evolution. |
| PubMedSearch : Chen_2003_J.Hum.Genet_48_164 |
| PubMedID: 12730717 |
| Gene_locus related to this paper: human-RBBP9 |
| Gene_locus | human-RBBP9 |
Chen J, Ji C, Gu S, Zhao E, Dai J, Huang L, Qian J, Ying K, Xie Y, Mao Y (2003)
Isolation and identification of a novel cDNA that encodes human yrdC protein
J Hum Genet
48 :164
Chen J, Ji C, Gu S, Zhao E, Dai J, Huang L, Qian J, Ying K, Xie Y, Mao Y (2003)
J Hum Genet
48 :164