| Title : Regioisomeric 5(3)-aminomethyl-3(5)-phenylisoxazoles: synthesis, spectroscopic discrimination, and muscarinic activity - Dannhardt_1995_Arch.Pharm.(Weinheim)_328_437 |
| Author(s) : Dannhardt G , Lambrecht G , Laufer S , Mutschler E , Schweiger J |
| Ref : Arch Pharm (Weinheim) , 328 :437 , 1995 |
|
Abstract :
The regioselective synthesis of isomeric 5(3)-aminomethyl-3(5)-phenyl isoxazoles using different methods is described. Spectroscopic data, especially mass spectrometric fragmentation, were used to identify and characterize the regioisomers. The muscarinic activity of these isoxazoles was assayed on isolated guinea-pig ileum and atria as well as on isolated rabbit vas deferens. |
| PubMedSearch : Dannhardt_1995_Arch.Pharm.(Weinheim)_328_437 |
| PubMedID: 7611839 |
Dannhardt G, Lambrecht G, Laufer S, Mutschler E, Schweiger J (1995)
Regioisomeric 5(3)-aminomethyl-3(5)-phenylisoxazoles: synthesis, spectroscopic discrimination, and muscarinic activity
Arch Pharm (Weinheim)
328 :437
Dannhardt G, Lambrecht G, Laufer S, Mutschler E, Schweiger J (1995)
Arch Pharm (Weinheim)
328 :437