Title : Human Exposure and Risk From Indoor Use of Chlorpyrifos - Gibson_1998_Environ.Health.Perspect_106_303
Author(s) : Gibson JE , Peterson RKD , Shurdut BA
Ref : Environmental Health Perspectives , 106 :303 , 1998
Abstract :

The toxicity, exposure, and risk from chlorpyrifos are briefly discussed in juxtaposition with two recent articles in Environmental Health Perspectives concerning potential exposures to children. In studies conducted according to EPA guidelines, chlorpyrifos has been shown not to be mutagenic, carcinogenic, or teratogenic, nor does it adversely affect reproduction. Chlorpyrifos toxicity does not occur in the absence of significant cholinesterase inhibition. If exposures are less than those that cause significant cholinesterase depression, then no signs or symptoms related to chlorpyrifos exposure occur. The weight of empirical evidence indicates that the risk of adults or children experiencing an adverse health effect from exposure to chlorpyrifos through both nondietary and dietary sources is negligible. Both the research supporting the registration of these products and their long history of widespread use suggest that unless these products are seriously misused, their margins of safety are wide enough to protect everyone with the potential to be exposed. A weight-of-evidence review of the entire scientific knowledge base relating to chlorpyrifos products supports these conclusions.

PubMedSearch : Gibson_1998_Environ.Health.Perspect_106_303
PubMedID: 9618344

Related information

Inhibitor Chlorpyrifos

Citations formats

Gibson JE, Peterson RKD, Shurdut BA (1998)
Human Exposure and Risk From Indoor Use of Chlorpyrifos
Environmental Health Perspectives 106 :303

Gibson JE, Peterson RKD, Shurdut BA (1998)
Environmental Health Perspectives 106 :303