| Title : Synthesis and Cholinesterase Inhibitory Activity of Selected Indole-Based Compounds - Groselj_2023_Acta.Chim.Slov_70_545 |
| Author(s) : Groselj U , Grsic M , Meden A , Knez D , Jukic M , Svete J , Gobec S |
| Ref : Acta Chim Slov , 70 :545 , 2023 |
|
Abstract :
Synthesis and anticholinesterase activity of 18 previously unpublished indole- and tryptophan-derived compounds are disclosed. These sp3-rich compounds containing an indole structural unit exhibit selective submicromolar inhibition of human butyrylcholinesterase (hBChE). The structures of the newly synthesized compounds were confirmed by 1H and 13C NMR, IR spectroscopy, and high-resolution mass spectrometry. |
| PubMedSearch : Groselj_2023_Acta.Chim.Slov_70_545 |
| PubMedID: 38124635 |
Groselj U, Grsic M, Meden A, Knez D, Jukic M, Svete J, Gobec S (2023)
Synthesis and Cholinesterase Inhibitory Activity of Selected Indole-Based Compounds
Acta Chim Slov
70 :545
Groselj U, Grsic M, Meden A, Knez D, Jukic M, Svete J, Gobec S (2023)
Acta Chim Slov
70 :545