Full name : Meden Anze
First name : Anze
Mail : University of Ljubljana, Faculty of Pharmacy, Askerceva 7, SI-1000, Ljubljana
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Country : Slovenia
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Comment
| Title : Tunable nucleofugality in carbamoyl-bearing covalent cholinesterase inhibitors - Meden_2025_bioRxiv__ |
| Author(s) : Meden A , Knez D , Chen X , Li L , Brazzolotto X , Zorman M , Pislar A , Perdih A , Modeste F , Dalle C , Denic M , Chantegreil F , Dias J , Ilas J , Kosmrlj J , Stojan J , Nachon F , Zhan C-G , Gobec S |
| Ref : bioRxiv , : , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_bioRxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : Targeting Neuroinflammation and Cognitive Decline: First-in-Class Dual Butyrylcholinesterase and p38alpha Mitogen-Activated Protein Kinase Inhibitors - Ferjancic Benetik_2025_J.Med.Chem__ |
| Author(s) : Ferjancic Benetik S , Proj M , Knez D , Kosak U , Meden A , Krajsek K , Pislar A , Horvat S , Svajger U , Tesic N , Pulkrabkova L , Soukup O , Skarka A , Andrys R , Brazzolotto X , Igert A , Nachon F , Dias J , Detka J , Gdula-Argasinska J , Wyska E , Szafarz M , Manik A , Plachtij N , Musilek K , Salat K , Obreza A , Gobec S |
| Ref : Journal of Medicinal Chemistry , : , 2025 |
| Abstract : |
| PubMedSearch : Ferjancic Benetik_2025_J.Med.Chem__ |
| PubMedID: 40779804 |
| Title : Targeting Neuroinflammation and Cognitive Decline: First-in-Class Dual Butyrylcholinesterase and p38alpha Mitogen-Activated Protein Kinase Inhibitors - Ferjancic Benetik_2025_J.Med.Chem__ |
| Author(s) : Ferjancic Benetik S , Proj M , Knez D , Kosak U , Meden A , Krajsek K , Pislar A , Horvat S , Svajger U , Tesic N , Pulkrabkova L , Soukup O , Skarka A , Andrys R , Brazzolotto X , Igert A , Nachon F , Dias J , Detka J , Gdula-Argasinska J , Wyska E , Szafarz M , Manik A , Plachtij N , Musilek K , Salat K , Obreza A , Gobec S |
| Ref : Journal of Medicinal Chemistry , : , 2025 |
| Abstract : |
| PubMedSearch : Ferjancic Benetik_2025_J.Med.Chem__ |
| PubMedID: 40779804 |
| Title : Pleiotropic prodrugs for both symptomatic and disease-modifying treatment of Alzheimer's disease - Meden_2025_Acta.Pharm.Sin.B_15_4807 |
| Author(s) : Meden A , Znidarsic N , Knez D , Wang Y , Xu Z , Yang H , Zhang W , Pislar A , Perdih A , Brezar SK , Grgurevic N , Pajk S , Sun H , Gobec S |
| Ref : Acta Pharm Sin B , 15 :4807 , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_Acta.Pharm.Sin.B_15_4807 |
| PubMedID: 41049759 |
| Title : Expanding the reactive chemistry toolbox - warhead screening for covalent butyrylcholinesterase inhibitors - Meden_2025_Chem.Biol.Interact_15ChEPon__41276059 |
| Author(s) : Meden A , Brazzolotto X , Dias J , Stojan J , Knez D , Gobec S |
| Ref : Chemico-Biological Interactions , :111841 , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_Chem.Biol.Interact_15ChEPon__41276059 |
| PubMedID: 41276059 |
| Title : Transforming ureas into carbamates: From allosteric p38alpha MAPK ligands to dual BChE\/p38alpha MAPK inhibitors - Ferjancic Benetik_2025_Bioorg.Chem_165_108998 |
| Author(s) : Benetik SF , Meden A , Knez D , Mastnak-Sokolov P , Kosak U , Horvat S , Pislar A , Andrys R , Musilek K , Detka J , Salat K , Obreza A , Gobec S |
| Ref : Bioorg Chem , 165 :108998 , 2025 |
| Abstract : |
| PubMedSearch : Ferjancic Benetik_2025_Bioorg.Chem_165_108998 |
| PubMedID: 40987175 |
| Gene_locus related to this paper: human-BCHE |
| Title : Transforming ureas into carbamates: From allosteric p38alpha MAPK ligands to dual BChE\/p38alpha MAPK inhibitors - Ferjancic Benetik_2025_Bioorg.Chem_165_108998 |
| Author(s) : Benetik SF , Meden A , Knez D , Mastnak-Sokolov P , Kosak U , Horvat S , Pislar A , Andrys R , Musilek K , Detka J , Salat K , Obreza A , Gobec S |
| Ref : Bioorg Chem , 165 :108998 , 2025 |
| Abstract : |
| PubMedSearch : Ferjancic Benetik_2025_Bioorg.Chem_165_108998 |
| PubMedID: 40987175 |
| Gene_locus related to this paper: human-BCHE |
| Title : Dual Cholinergic Modulation in Dementia: Quinuclidine Carbamates Targeting Butyrylcholinesterase and alpha7 Nicotinic Receptor - Mastnak-Sokolov_2025_Chem.Biol.Interact_15ChEPon__111830 |
| Author(s) : Mastnak-Sokolov P , Knez D , Meden A , Strasek Benedik N , Ferjancic Benetik S , Hrast Rambaher M , Zorman M , Nachon F , Brazzolotto X , Jardemark K , Jungholm O , Bruton J , Strandback E , Nyman T , Shahid M , Gobec S |
| Ref : Chemico-Biological Interactions , :111830 , 2025 |
| Abstract : |
| PubMedSearch : Mastnak-Sokolov_2025_Chem.Biol.Interact_15ChEPon__111830 |
| PubMedID: 41242410 |
| Gene_locus related to this paper: human-BCHE |
| Title : Expanding the reactive chemistry toolbox - warhead screening for covalent butyrylcholinesterase inhibitors - Meden_2025_Chem.Biol.Interact_15ChEPon__41276059 |
| Author(s) : Meden A , Brazzolotto X , Dias J , Stojan J , Knez D , Gobec S |
| Ref : Chemico-Biological Interactions , :111841 , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_Chem.Biol.Interact_15ChEPon__41276059 |
| PubMedID: 41276059 |
| Title : Dual Cholinergic Modulation in Dementia: Quinuclidine Carbamates Targeting Butyrylcholinesterase and alpha7 Nicotinic Receptor - Mastnak-Sokolov_2025_Chem.Biol.Interact_15ChEPon__111830 |
| Author(s) : Mastnak-Sokolov P , Knez D , Meden A , Strasek Benedik N , Ferjancic Benetik S , Hrast Rambaher M , Zorman M , Nachon F , Brazzolotto X , Jardemark K , Jungholm O , Bruton J , Strandback E , Nyman T , Shahid M , Gobec S |
| Ref : Chemico-Biological Interactions , :111830 , 2025 |
| Abstract : |
| PubMedSearch : Mastnak-Sokolov_2025_Chem.Biol.Interact_15ChEPon__111830 |
| PubMedID: 41242410 |
| Gene_locus related to this paper: human-BCHE |
| Title : Pleiotropic prodrugs for both symptomatic and disease-modifying treatment of Alzheimer's disease - Meden_2025_Acta.Pharm.Sin.B_15_4807 |
| Author(s) : Meden A , Znidarsic N , Knez D , Wang Y , Xu Z , Yang H , Zhang W , Pislar A , Perdih A , Brezar SK , Grgurevic N , Pajk S , Sun H , Gobec S |
| Ref : Acta Pharm Sin B , 15 :4807 , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_Acta.Pharm.Sin.B_15_4807 |
| PubMedID: 41049759 |
| Title : Targeting Neuroinflammation and Cognitive Decline: First-in-Class Dual Butyrylcholinesterase and p38alpha Mitogen-Activated Protein Kinase Inhibitors - Ferjancic Benetik_2025_J.Med.Chem__ |
| Author(s) : Ferjancic Benetik S , Proj M , Knez D , Kosak U , Meden A , Krajsek K , Pislar A , Horvat S , Svajger U , Tesic N , Pulkrabkova L , Soukup O , Skarka A , Andrys R , Brazzolotto X , Igert A , Nachon F , Dias J , Detka J , Gdula-Argasinska J , Wyska E , Szafarz M , Manik A , Plachtij N , Musilek K , Salat K , Obreza A , Gobec S |
| Ref : Journal of Medicinal Chemistry , : , 2025 |
| Abstract : |
| PubMedSearch : Ferjancic Benetik_2025_J.Med.Chem__ |
| PubMedID: 40779804 |
| Title : Transforming ureas into carbamates: From allosteric p38alpha MAPK ligands to dual BChE\/p38alpha MAPK inhibitors - Ferjancic Benetik_2025_Bioorg.Chem_165_108998 |
| Author(s) : Benetik SF , Meden A , Knez D , Mastnak-Sokolov P , Kosak U , Horvat S , Pislar A , Andrys R , Musilek K , Detka J , Salat K , Obreza A , Gobec S |
| Ref : Bioorg Chem , 165 :108998 , 2025 |
| Abstract : |
| PubMedSearch : Ferjancic Benetik_2025_Bioorg.Chem_165_108998 |
| PubMedID: 40987175 |
| Gene_locus related to this paper: human-BCHE |
| Title : Tunable nucleofugality in carbamoyl-bearing covalent cholinesterase inhibitors - Meden_2025_bioRxiv__ |
| Author(s) : Meden A , Knez D , Chen X , Li L , Brazzolotto X , Zorman M , Pislar A , Perdih A , Modeste F , Dalle C , Denic M , Chantegreil F , Dias J , Ilas J , Kosmrlj J , Stojan J , Nachon F , Zhan C-G , Gobec S |
| Ref : bioRxiv , : , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_bioRxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : Expanding the reactive chemistry toolbox - warhead screening for covalent butyrylcholinesterase inhibitors - Meden_2025_Chem.Biol.Interact_15ChEPon__41276059 |
| Author(s) : Meden A , Brazzolotto X , Dias J , Stojan J , Knez D , Gobec S |
| Ref : Chemico-Biological Interactions , :111841 , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_Chem.Biol.Interact_15ChEPon__41276059 |
| PubMedID: 41276059 |
| Title : Tunable nucleofugality in carbamoyl-bearing covalent cholinesterase inhibitors - Meden_2025_bioRxiv__ |
| Author(s) : Meden A , Knez D , Chen X , Li L , Brazzolotto X , Zorman M , Pislar A , Perdih A , Modeste F , Dalle C , Denic M , Chantegreil F , Dias J , Ilas J , Kosmrlj J , Stojan J , Nachon F , Zhan C-G , Gobec S |
| Ref : bioRxiv , : , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_bioRxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : Dual Cholinergic Modulation in Dementia: Quinuclidine Carbamates Targeting Butyrylcholinesterase and alpha7 Nicotinic Receptor - Mastnak-Sokolov_2025_Chem.Biol.Interact_15ChEPon__111830 |
| Author(s) : Mastnak-Sokolov P , Knez D , Meden A , Strasek Benedik N , Ferjancic Benetik S , Hrast Rambaher M , Zorman M , Nachon F , Brazzolotto X , Jardemark K , Jungholm O , Bruton J , Strandback E , Nyman T , Shahid M , Gobec S |
| Ref : Chemico-Biological Interactions , :111830 , 2025 |
| Abstract : |
| PubMedSearch : Mastnak-Sokolov_2025_Chem.Biol.Interact_15ChEPon__111830 |
| PubMedID: 41242410 |
| Gene_locus related to this paper: human-BCHE |
| Title : Pleiotropic prodrugs for both symptomatic and disease-modifying treatment of Alzheimer's disease - Meden_2025_Acta.Pharm.Sin.B_15_4807 |
| Author(s) : Meden A , Znidarsic N , Knez D , Wang Y , Xu Z , Yang H , Zhang W , Pislar A , Perdih A , Brezar SK , Grgurevic N , Pajk S , Sun H , Gobec S |
| Ref : Acta Pharm Sin B , 15 :4807 , 2025 |
| Abstract : |
| PubMedSearch : Meden_2025_Acta.Pharm.Sin.B_15_4807 |
| PubMedID: 41049759 |
| Title : Disentangling the formation, mechanism, and evolvement of the covalent methanesulfonyl fluoride acetylcholinesterase adduct: Insights into an aged-like inactive complex susceptible to reactivation by a combination of nucleophiles - Stojan_2024_Protein.Sci_33_e4977 |
| Author(s) : Stojan J , Pesaresi A , Meden A , Lamba D |
| Ref : Protein Science , 33 :e4977 , 2024 |
| Abstract : |
| PubMedSearch : Stojan_2024_Protein.Sci_33_e4977 |
| PubMedID: 38591646 |
| Title : Disentangling the formation, mechanism, and evolvement of the covalent methanesulfonyl fluoride acetylcholinesterase adduct: Insights into an aged-like inactive complex susceptible to reactivation by a combination of nucleophiles - Stojan_2024_Protein.Sci_33_e4977 |
| Author(s) : Stojan J , Pesaresi A , Meden A , Lamba D |
| Ref : Protein Science , 33 :e4977 , 2024 |
| Abstract : |
| PubMedSearch : Stojan_2024_Protein.Sci_33_e4977 |
| PubMedID: 38591646 |
| Title : Disentangling the formation, mechanism, and evolvement of the covalent methanesulfonyl fluoride acetylcholinesterase adduct: Insights into an aged-like inactive complex susceptible to reactivation by a combination of nucleophiles - Stojan_2024_Protein.Sci_33_e4977 |
| Author(s) : Stojan J , Pesaresi A , Meden A , Lamba D |
| Ref : Protein Science , 33 :e4977 , 2024 |
| Abstract : |
| PubMedSearch : Stojan_2024_Protein.Sci_33_e4977 |
| PubMedID: 38591646 |
| Title : 8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases - Knez_2023_Acta.Pharmaceutica.Sinica.B_13_2152 |
| Author(s) : Knez D , Diez-Iriepa D , Chioua M , Gottinger A , Denic M , Chantegreil F , Nachon F , Brazzolotto X , Skrzypczak-Wiercioch A , Meden A , Pislar A , Kos J , Zakelj S , Stojan J , Salat K , Serrano J , Patricia Fernandez AP , Sanchez-Garcia A , Martinez-Murillo R , Binda C , Lopez-Munoz F , Gobec S , Marco-Contelles J |
| Ref : Acta Pharmaceutica Sinica B , 13 :2152 , 2023 |
| Abstract : |
| PubMedSearch : Knez_2023_Acta.Pharmaceutica.Sinica.B_13_2152 |
| PubMedID: 37250172 |
| Gene_locus related to this paper: human-BCHE |
| Title : Pseudo-irreversible butyrylcholinesterase inhibitors: Structure-activity relationships, computational and crystallographic study of the N-dialkyl O-arylcarbamate warhead - Meden_2023_Eur.J.Med.Chem_247_115048 |
| Author(s) : Meden A , Knez D , Brazzolotto X , Modeste F , Perdih A , Pislar A , Zorman M , Zorovic M , Denic M , Pajk S , Zivin M , Nachon F , Gobec S |
| Ref : Eur Journal of Medicinal Chemistry , 247 :115048 , 2023 |
| Abstract : |
| PubMedSearch : Meden_2023_Eur.J.Med.Chem_247_115048 |
| PubMedID: 36586299 |
| Gene_locus related to this paper: human-BCHE |
| Title : Synthesis and Cholinesterase Inhibitory Activity of Selected Indole-Based Compounds - Groselj_2023_Acta.Chim.Slov_70_545 |
| Author(s) : Groselj U , Grsic M , Meden A , Knez D , Jukic M , Svete J , Gobec S |
| Ref : Acta Chim Slov , 70 :545 , 2023 |
| Abstract : |
| PubMedSearch : Groselj_2023_Acta.Chim.Slov_70_545 |
| PubMedID: 38124635 |
| Title : Synthesis and Cholinesterase Inhibitory Activity of Selected Indole-Based Compounds - Groselj_2023_Acta.Chim.Slov_70_545 |
| Author(s) : Groselj U , Grsic M , Meden A , Knez D , Jukic M , Svete J , Gobec S |
| Ref : Acta Chim Slov , 70 :545 , 2023 |
| Abstract : |
| PubMedSearch : Groselj_2023_Acta.Chim.Slov_70_545 |
| PubMedID: 38124635 |
| Title : Synthesis and Cholinesterase Inhibitory Activity of Selected Indole-Based Compounds - Groselj_2023_Acta.Chim.Slov_70_545 |
| Author(s) : Groselj U , Grsic M , Meden A , Knez D , Jukic M , Svete J , Gobec S |
| Ref : Acta Chim Slov , 70 :545 , 2023 |
| Abstract : |
| PubMedSearch : Groselj_2023_Acta.Chim.Slov_70_545 |
| PubMedID: 38124635 |
| Title : 8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases - Knez_2023_Acta.Pharmaceutica.Sinica.B_13_2152 |
| Author(s) : Knez D , Diez-Iriepa D , Chioua M , Gottinger A , Denic M , Chantegreil F , Nachon F , Brazzolotto X , Skrzypczak-Wiercioch A , Meden A , Pislar A , Kos J , Zakelj S , Stojan J , Salat K , Serrano J , Patricia Fernandez AP , Sanchez-Garcia A , Martinez-Murillo R , Binda C , Lopez-Munoz F , Gobec S , Marco-Contelles J |
| Ref : Acta Pharmaceutica Sinica B , 13 :2152 , 2023 |
| Abstract : |
| PubMedSearch : Knez_2023_Acta.Pharmaceutica.Sinica.B_13_2152 |
| PubMedID: 37250172 |
| Gene_locus related to this paper: human-BCHE |
| Title : 8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases - Knez_2023_Acta.Pharmaceutica.Sinica.B_13_2152 |
| Author(s) : Knez D , Diez-Iriepa D , Chioua M , Gottinger A , Denic M , Chantegreil F , Nachon F , Brazzolotto X , Skrzypczak-Wiercioch A , Meden A , Pislar A , Kos J , Zakelj S , Stojan J , Salat K , Serrano J , Patricia Fernandez AP , Sanchez-Garcia A , Martinez-Murillo R , Binda C , Lopez-Munoz F , Gobec S , Marco-Contelles J |
| Ref : Acta Pharmaceutica Sinica B , 13 :2152 , 2023 |
| Abstract : |
| PubMedSearch : Knez_2023_Acta.Pharmaceutica.Sinica.B_13_2152 |
| PubMedID: 37250172 |
| Gene_locus related to this paper: human-BCHE |
| Title : Pseudo-irreversible butyrylcholinesterase inhibitors: Structure-activity relationships, computational and crystallographic study of the N-dialkyl O-arylcarbamate warhead - Meden_2023_Eur.J.Med.Chem_247_115048 |
| Author(s) : Meden A , Knez D , Brazzolotto X , Modeste F , Perdih A , Pislar A , Zorman M , Zorovic M , Denic M , Pajk S , Zivin M , Nachon F , Gobec S |
| Ref : Eur Journal of Medicinal Chemistry , 247 :115048 , 2023 |
| Abstract : |
| PubMedSearch : Meden_2023_Eur.J.Med.Chem_247_115048 |
| PubMedID: 36586299 |
| Gene_locus related to this paper: human-BCHE |
| Title : Pseudo-irreversible butyrylcholinesterase inhibitors: Structure-activity relationships, computational and crystallographic study of the N-dialkyl O-arylcarbamate warhead - Meden_2023_Eur.J.Med.Chem_247_115048 |
| Author(s) : Meden A , Knez D , Brazzolotto X , Modeste F , Perdih A , Pislar A , Zorman M , Zorovic M , Denic M , Pajk S , Zivin M , Nachon F , Gobec S |
| Ref : Eur Journal of Medicinal Chemistry , 247 :115048 , 2023 |
| Abstract : |
| PubMedSearch : Meden_2023_Eur.J.Med.Chem_247_115048 |
| PubMedID: 36586299 |
| Gene_locus related to this paper: human-BCHE |
| Title : Repurposing of 8-Hydroxyquinoline-based Butyrylcholinesterase and Cathepsin B Ligands as Potent Non-peptidic Deoxyribonuclease I Inhibitors - Gajic_2022_ChemMedChem__ |
| Author(s) : Gajic M , Knez D , Sosic I , Mravljak J , Meden A , Kosak U , Leitzbach L , George S , Hofmann B , Zivkovic A , Steinhilber D , Stark H , Gobec S , Smelcerovic A , Anderluh M |
| Ref : ChemMedChem , : , 2022 |
| Abstract : |
| PubMedSearch : Gajic_2022_ChemMedChem__ |
| PubMedID: 34994078 |
| Title : Pseudo-irreversible butyrylcholinesterase inhibitors: SAR, kinetic, computational, and crystallographic study of the N-dialkyl O-arylcarbamate warhead - Meden_2022_Chemrxiv__ |
| Author(s) : Meden A , Knez D , Brazzolotto X , Modeste F , Perdih A , Pislar A , Zorman M , Denic M , Pajk S , Nachon F , Gobec S |
| Ref : Chemrxiv , : , 2022 |
| Abstract : |
| PubMedSearch : Meden_2022_Chemrxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : Repurposing of 8-Hydroxyquinoline-based Butyrylcholinesterase and Cathepsin B Ligands as Potent Non-peptidic Deoxyribonuclease I Inhibitors - Gajic_2022_ChemMedChem__ |
| Author(s) : Gajic M , Knez D , Sosic I , Mravljak J , Meden A , Kosak U , Leitzbach L , George S , Hofmann B , Zivkovic A , Steinhilber D , Stark H , Gobec S , Smelcerovic A , Anderluh M |
| Ref : ChemMedChem , : , 2022 |
| Abstract : |
| PubMedSearch : Gajic_2022_ChemMedChem__ |
| PubMedID: 34994078 |
| Title : From tryptophan-based amides to tertiary amines: Optimization of a butyrylcholinesterase inhibitor series - Meden_2022_Eur.J.Med.Chem_230_114248 |
| Author(s) : Meden A , Knez D , Brazzolotto X , Nachon F , Dias J , Svete J , Stojan J , Groselj U , Gobec S |
| Ref : Eur Journal of Medicinal Chemistry , 230 :114248 , 2022 |
| Abstract : |
| PubMedSearch : Meden_2022_Eur.J.Med.Chem_230_114248 |
| PubMedID: 35299116 |
| Title : Repurposing of 8-Hydroxyquinoline-based Butyrylcholinesterase and Cathepsin B Ligands as Potent Non-peptidic Deoxyribonuclease I Inhibitors - Gajic_2022_ChemMedChem__ |
| Author(s) : Gajic M , Knez D , Sosic I , Mravljak J , Meden A , Kosak U , Leitzbach L , George S , Hofmann B , Zivkovic A , Steinhilber D , Stark H , Gobec S , Smelcerovic A , Anderluh M |
| Ref : ChemMedChem , : , 2022 |
| Abstract : |
| PubMedSearch : Gajic_2022_ChemMedChem__ |
| PubMedID: 34994078 |
| Title : From tryptophan-based amides to tertiary amines: Optimization of a butyrylcholinesterase inhibitor series - Meden_2022_Eur.J.Med.Chem_230_114248 |
| Author(s) : Meden A , Knez D , Brazzolotto X , Nachon F , Dias J , Svete J , Stojan J , Groselj U , Gobec S |
| Ref : Eur Journal of Medicinal Chemistry , 230 :114248 , 2022 |
| Abstract : |
| PubMedSearch : Meden_2022_Eur.J.Med.Chem_230_114248 |
| PubMedID: 35299116 |
| Title : Pseudo-irreversible butyrylcholinesterase inhibitors: SAR, kinetic, computational, and crystallographic study of the N-dialkyl O-arylcarbamate warhead - Meden_2022_Chemrxiv__ |
| Author(s) : Meden A , Knez D , Brazzolotto X , Modeste F , Perdih A , Pislar A , Zorman M , Denic M , Pajk S , Nachon F , Gobec S |
| Ref : Chemrxiv , : , 2022 |
| Abstract : |
| PubMedSearch : Meden_2022_Chemrxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : From tryptophan-based amides to tertiary amines: Optimization of a butyrylcholinesterase inhibitor series - Meden_2022_Eur.J.Med.Chem_230_114248 |
| Author(s) : Meden A , Knez D , Brazzolotto X , Nachon F , Dias J , Svete J , Stojan J , Groselj U , Gobec S |
| Ref : Eur Journal of Medicinal Chemistry , 230 :114248 , 2022 |
| Abstract : |
| PubMedSearch : Meden_2022_Eur.J.Med.Chem_230_114248 |
| PubMedID: 35299116 |
| Title : Pseudo-irreversible butyrylcholinesterase inhibitors: SAR, kinetic, computational, and crystallographic study of the N-dialkyl O-arylcarbamate warhead - Meden_2022_Chemrxiv__ |
| Author(s) : Meden A , Knez D , Brazzolotto X , Modeste F , Perdih A , Pislar A , Zorman M , Denic M , Pajk S , Nachon F , Gobec S |
| Ref : Chemrxiv , : , 2022 |
| Abstract : |
| PubMedSearch : Meden_2022_Chemrxiv__ |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE |
| Title : 4-Phenethyl-1-Propargylpiperidine-Derived Dual Inhibitors of Butyrylcholinesterase and Monoamine Oxidase B - Mazej_2021_Molecules_26_ |
| Author(s) : Mazej T , Knez D , Meden A , Gobec S , Sova M |
| Ref : Molecules , 26 : , 2021 |
| Abstract : |
| PubMedSearch : Mazej_2021_Molecules_26_ |
| PubMedID: 34299393 |
| Title : 4-Phenethyl-1-Propargylpiperidine-Derived Dual Inhibitors of Butyrylcholinesterase and Monoamine Oxidase B - Mazej_2021_Molecules_26_ |
| Author(s) : Mazej T , Knez D , Meden A , Gobec S , Sova M |
| Ref : Molecules , 26 : , 2021 |
| Abstract : |
| PubMedSearch : Mazej_2021_Molecules_26_ |
| PubMedID: 34299393 |
| Title : 4-Phenethyl-1-Propargylpiperidine-Derived Dual Inhibitors of Butyrylcholinesterase and Monoamine Oxidase B - Mazej_2021_Molecules_26_ |
| Author(s) : Mazej T , Knez D , Meden A , Gobec S , Sova M |
| Ref : Molecules , 26 : , 2021 |
| Abstract : |
| PubMedSearch : Mazej_2021_Molecules_26_ |
| PubMedID: 34299393 |
| Title : Structure-activity relationship study of tryptophan-based butyrylcholinesterase inhibitors - Meden_2020_Eur.J.Med.Chem_208_112766 |
| Author(s) : Meden A , Knez D , Malikowska-Racia N , Brazzolotto X , Nachon F , Svete J , Salat K , Groselj U , Gobec S |
| Ref : Eur Journal of Medicinal Chemistry , 208 :112766 , 2020 |
| Abstract : |
| PubMedSearch : Meden_2020_Eur.J.Med.Chem_208_112766 |
| PubMedID: 32919297 |
| Gene_locus related to this paper: human-BCHE |
| Title : Structure-activity relationship study of tryptophan-based butyrylcholinesterase inhibitors - Meden_2020_Eur.J.Med.Chem_208_112766 |
| Author(s) : Meden A , Knez D , Malikowska-Racia N , Brazzolotto X , Nachon F , Svete J , Salat K , Groselj U , Gobec S |
| Ref : Eur Journal of Medicinal Chemistry , 208 :112766 , 2020 |
| Abstract : |
| PubMedSearch : Meden_2020_Eur.J.Med.Chem_208_112766 |
| PubMedID: 32919297 |
| Gene_locus related to this paper: human-BCHE |
| Title : Structure-activity relationship study of tryptophan-based butyrylcholinesterase inhibitors - Meden_2020_Eur.J.Med.Chem_208_112766 |
| Author(s) : Meden A , Knez D , Malikowska-Racia N , Brazzolotto X , Nachon F , Svete J , Salat K , Groselj U , Gobec S |
| Ref : Eur Journal of Medicinal Chemistry , 208 :112766 , 2020 |
| Abstract : |
| PubMedSearch : Meden_2020_Eur.J.Med.Chem_208_112766 |
| PubMedID: 32919297 |
| Gene_locus related to this paper: human-BCHE |
| Title : Tryptophan-derived butyrylcholinesterase inhibitors as promising leads against Alzheimer's disease - Meden_2019_Chem.Commun.(Camb)_55_3765 |
| Author(s) : Meden A , Knez D , Jukic M , Brazzolotto X , Grsic M , Pislar A , Zahirovic A , Kos J , Nachon F , Svete J , Gobec S , Groselj U |
| Ref : Chem Commun (Camb) , 55 :3765 , 2019 |
| Abstract : |
| PubMedSearch : Meden_2019_Chem.Commun.(Camb)_55_3765 |
| PubMedID: 30864579 |
| Gene_locus related to this paper: human-BCHE |
| Title : Tryptophan-derived butyrylcholinesterase inhibitors as promising leads against Alzheimer's disease - Meden_2019_Chem.Commun.(Camb)_55_3765 |
| Author(s) : Meden A , Knez D , Jukic M , Brazzolotto X , Grsic M , Pislar A , Zahirovic A , Kos J , Nachon F , Svete J , Gobec S , Groselj U |
| Ref : Chem Commun (Camb) , 55 :3765 , 2019 |
| Abstract : |
| PubMedSearch : Meden_2019_Chem.Commun.(Camb)_55_3765 |
| PubMedID: 30864579 |
| Gene_locus related to this paper: human-BCHE |
| Title : Tryptophan-derived butyrylcholinesterase inhibitors as promising leads against Alzheimer's disease - Meden_2019_Chem.Commun.(Camb)_55_3765 |
| Author(s) : Meden A , Knez D , Jukic M , Brazzolotto X , Grsic M , Pislar A , Zahirovic A , Kos J , Nachon F , Svete J , Gobec S , Groselj U |
| Ref : Chem Commun (Camb) , 55 :3765 , 2019 |
| Abstract : |
| PubMedSearch : Meden_2019_Chem.Commun.(Camb)_55_3765 |
| PubMedID: 30864579 |
| Gene_locus related to this paper: human-BCHE |