Kamita_2010_J.Pestic.Sci_35_265

Reference

Title : Juvenile hormone esterase: biochemistry and structure - Kamita_2010_J.Pestic.Sci_35_265
Author(s) : Kamita SG , Hammock BD
Ref : Journal of Pesticide Science , 35 :265 , 2010
Abstract :

Normal insect development requires a precisely timed, precipitous drop in hemolymph juvenile hormone (JH) titer. This drop occurs through a coordinated halt in JH biosynthesis and increase in JH metabolism. In many species, JH esterase (JHE) is critical for metabolism of the resonance-stabilized methyl ester of JH. JHE metabolizes JH with a high kcat/KM ratio that results primarily from an exceptionally low KM. Here we review the biochemistry and structure of authentic and recombinant JHEs from six insect orders, and present updated diagnostic criteria that help to distinguish JHEs from other carboxylesterases. The use of a JHE-encoding gene to improve the insecticidal efficacy of biopesticides is also discussed.

PubMedSearch : Kamita_2010_J.Pestic.Sci_35_265
PubMedID: 23543805

Related information

Substrate HEPTAT
Family HEPTAT    Juvenile_hormone_esterase

Citations formats

Kamita SG, Hammock BD (2010)
Juvenile hormone esterase: biochemistry and structure
Journal of Pesticide Science 35 :265

Kamita SG, Hammock BD (2010)
Journal of Pesticide Science 35 :265