| Title : [Effective reversal of muscle relaxation by rocuronium using sugammadex in a patient with myasthenia gravis undergoing laparoscopic cholecystectomy] - Komasawa_2011_Masui_60_476 |
| Author(s) : Komasawa N , Noma H , Sugi T , Sukenaga N , Kakiuchi H |
| Ref : Masui , 60 :476 , 2011 |
|
Abstract :
As myasthenia gravis affects neuromuscular transmission, these patients show various responses to neuromuscular blocking drugs. We report a successful use of the sugammadex in a myasthenic patient to reverse rocuronium-induced neuromuscular block. A 69-year-old woman was scheduled for laparoscopic cholecystectomy and total of rocuronium 20 mg was administered. After spontaneous recovery of T1, we administered sugammadex 200mg intravenously, reversing neuromuscular blockade to a train-of-four ratio (T4/T1) of 100% within 30 sec. Sugammadex can be used to reverse rocuronium-induced neuromuscular blockade in patients with myasthenia gravis, thereby avoiding the need for reversal with acetylcholinesterase inhibitors. |
| PubMedSearch : Komasawa_2011_Masui_60_476 |
| PubMedID: 21520600 |
| Inhibitor | Rocuronium |
| Chemical | Sugammadex |
Komasawa N, Noma H, Sugi T, Sukenaga N, Kakiuchi H (2011)
[Effective reversal of muscle relaxation by rocuronium using sugammadex in a patient with myasthenia gravis undergoing laparoscopic cholecystectomy]
Masui
60 :476
Komasawa N, Noma H, Sugi T, Sukenaga N, Kakiuchi H (2011)
Masui
60 :476