Title : High expression of NDRG3 correlates with poor prognosis in gastric cancer patients - Liu_2021_Rev.Esp.Enferm.Dig_113_524 |
Author(s) : Liu Y , Xia J , Zhou Y , Shao S |
Ref : Rev Esp Enferm Dig , 113 :524 , 2021 |
Abstract :
INTRODUCTION: N-myc downstream-regulated gene 3 (NDRG3) is an important member of the NDRG family and is linked with malignant tumors. However, the relationship between NDRG3 and gastric cancer (GC) is vague. MATERIAL AND METHODS: Western blot, qRT-PCR and immunohistochemistry (IHC) detected the expression of NDRG3 in GC cell lines and GC tissues; public databases were used to analyze NDRG3 in GC patients and the association with EBV infection. RESULTS: NDRG3 was up-regulated in GC cell lines and tissues. IHC data suggested that NDRG3 was correlated with histologic grade (p = 0.006) and is associated with patient survival. DISCUSSION: thus, NDRG3 may be a novel predictor of GC prognosis. |
PubMedSearch : Liu_2021_Rev.Esp.Enferm.Dig_113_524 |
PubMedID: 33562989 |
Gene_locus related to this paper: human-NDRG3 |
Gene_locus | human-NDRG3 |
Liu Y, Xia J, Zhou Y, Shao S (2021)
High expression of NDRG3 correlates with poor prognosis in gastric cancer patients
Rev Esp Enferm Dig
113 :524
Liu Y, Xia J, Zhou Y, Shao S (2021)
Rev Esp Enferm Dig
113 :524