| Title : An esterase-activatable curcumin prodrug for tumor-targeting therapy - Liu_2022_Chem.Commun.(Camb)__ |
| Author(s) : Liu L , Zhang L , Tao M , Wang M , Dong L , Hai Z |
| Ref : Chem Commun (Camb) , : , 2022 |
|
Abstract :
A tumor-targeting therapy strategy is urgently needed to increase the accumulation of drugs in tumors and reduce the side effects in normal tissues. Herein, we developed an esterase-activatable curcumin prodrug Cur-RGD for tumor-targeting therapy. Armed with the tumor-targeting RGD peptide and in situ esterase-triggered drug release, this prodrug Cur-RGD can efficiently improve the therapeutic effect of curcumin in tumors. |
| PubMedSearch : Liu_2022_Chem.Commun.(Camb)__ |
| PubMedID: 36373630 |
Liu L, Zhang L, Tao M, Wang M, Dong L, Hai Z (2022)
An esterase-activatable curcumin prodrug for tumor-targeting therapy
Chem Commun (Camb)
:
Liu L, Zhang L, Tao M, Wang M, Dong L, Hai Z (2022)
Chem Commun (Camb)
: