Lopez_2002_Life.Sci_71_2521

Reference

Title : Acetylcholinesterase inhibitory activity of some Amaryllidaceae alkaloids and Narcissus extracts - Lopez_2002_Life.Sci_71_2521
Author(s) : Lopez S , Bastida J , Viladomat F , Codina C
Ref : Life Sciences , 71 :2521 , 2002
Abstract : Amaryllidaceous plants produce pharmacologically active alkaloids, galanthamine being the most interesting for its use in the treatment of Alzheimer's disease as a cholinesterase inhibitor. The aim of this work was to test 23 pure Amaryllidaceae alkaloids and 26 extracts from different species of the genus Narcissus for their acetylcholinesterase inhibitory activity using galanthamine as a reference. Only seven alkaloids, belonging to the galanthamine and lycorine skeleton types, exhibited such an effect, sanguinine being the most active, even more than galanthamine. All the extracts with the highest acetylcholinesterase inhibitory activity contained galanthamine except that of N. assoanus, a lycorine type alkaloid-bearing species.
ESTHER : Lopez_2002_Life.Sci_71_2521
PubMedSearch : Lopez_2002_Life.Sci_71_2521
PubMedID: 12270757

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Citations formats

Lopez S, Bastida J, Viladomat F, Codina C (2002)
Acetylcholinesterase inhibitory activity of some Amaryllidaceae alkaloids and Narcissus extracts
Life Sciences 71 :2521

Lopez S, Bastida J, Viladomat F, Codina C (2002)
Life Sciences 71 :2521