| Title : Colorimetric Detectors Based on Acetylcholinesterase and Its Construction - Pohanka_2010_Mil.Med.Sci.Lett_79_9 |
| Author(s) : Pohanka M , Vlcek V , Karasova JZ , Kuca K , Cabal J |
| Ref : Military Medical Science Letters , 79 :9 , 2010 |
|
Abstract :
Colorimetric detectors based on recognition capability of acetylcholinesterase (AChE) are a suitable tool for fast but sensitive detection of nerve agents and some pesticides based on AChE inhibition. In this review article, basic biochemical methods appropriate for colorimetric estimation of AChE enzymatic activity are presented. Moreover, the available matrices suitable for construction of dipsticks and chemical as well as physical immobilization protocols for AChE binding on matrice surface are described, too. Detehit and ChP-71 are indicated as typical colorimetric detectors for assay of nerve agents. |
| PubMedSearch : Pohanka_2010_Mil.Med.Sci.Lett_79_9 |
| PubMedID: |
Pohanka M, Vlcek V, Karasova JZ, Kuca K, Cabal J (2010)
Colorimetric Detectors Based on Acetylcholinesterase and Its Construction
Military Medical Science Letters
79 :9
Pohanka M, Vlcek V, Karasova JZ, Kuca K, Cabal J (2010)
Military Medical Science Letters
79 :9