Schonknecht_2013_Science_339_1207

Reference

Title : Gene transfer from bacteria and archaea facilitated evolution of an extremophilic eukaryote - Schonknecht_2013_Science_339_1207
Author(s) : Schonknecht G , Chen WH , Ternes CM , Barbier GG , Shrestha RP , Stanke M , Brautigam A , Baker BJ , Banfield JF , Garavito RM , Carr K , Wilkerson C , Rensing SA , Gagneul D , Dickenson NE , Oesterhelt C , Lercher MJ , Weber AP
Ref : Science , 339 :1207 , 2013
Abstract :

Some microbial eukaryotes, such as the extremophilic red alga Galdieria sulphuraria, live in hot, toxic metal-rich, acidic environments. To elucidate the underlying molecular mechanisms of adaptation, we sequenced the 13.7-megabase genome of G. sulphuraria. This alga shows an enormous metabolic flexibility, growing either photoautotrophically or heterotrophically on more than 50 carbon sources. Environmental adaptation seems to have been facilitated by horizontal gene transfer from various bacteria and archaea, often followed by gene family expansion. At least 5% of protein-coding genes of G. sulphuraria were probably acquired horizontally. These proteins are involved in ecologically important processes ranging from heavy-metal detoxification to glycerol uptake and metabolism. Thus, our findings show that a pan-domain gene pool has facilitated environmental adaptation in this unicellular eukaryote.

PubMedSearch : Schonknecht_2013_Science_339_1207
PubMedID: 23471408
Gene_locus related to this paper: galsu-m2y8v3 , galsu-m2xs14 , galsu-m2w341

Related information

Gene_locus galsu-m2y8v3    galsu-m2xs14    galsu-m2w341

Citations formats

Schonknecht G, Chen WH, Ternes CM, Barbier GG, Shrestha RP, Stanke M, Brautigam A, Baker BJ, Banfield JF, Garavito RM, Carr K, Wilkerson C, Rensing SA, Gagneul D, Dickenson NE, Oesterhelt C, Lercher MJ, Weber AP (2013)
Gene transfer from bacteria and archaea facilitated evolution of an extremophilic eukaryote
Science 339 :1207

Schonknecht G, Chen WH, Ternes CM, Barbier GG, Shrestha RP, Stanke M, Brautigam A, Baker BJ, Banfield JF, Garavito RM, Carr K, Wilkerson C, Rensing SA, Gagneul D, Dickenson NE, Oesterhelt C, Lercher MJ, Weber AP (2013)
Science 339 :1207