Thatcher_2012_Mol.Plant.Microbe.Interact_25_180

Reference

Title : A highly conserved effector in Fusarium oxysporum is required for full virulence on Arabidopsis - Thatcher_2012_Mol.Plant.Microbe.Interact_25_180
Author(s) : Thatcher LF , Gardiner DM , Kazan K , Manners JM
Ref : Mol Plant Microbe Interact , 25 :180 , 2012
Abstract :

Secreted-in-xylem (SIX) proteins of the vascular wilt pathogen Fusarium oxysporum f. sp. lycopersici are secreted during infection of tomato and function in virulence or avirulence. F. oxysporum formae speciales have specific host ranges but the roles of SIX proteins in diverse hosts are unknown. We identified homologs of F. oxysporum f. sp. lycopersici SIX1, SIX4, SIX8, and SIX9 in the genome of Arabidopsis infecting isolate Fo5176. A SIX4 homolog (termed Fo5176-SIX4) differed from that of F. oxysporum f. sp. lycopersici (Fol-SIX4) by only two amino acids, and its expression was induced during infection of Arabidopsis. Transgenic Arabidopsis plants constitutively expressing Fo5176-SIX4 had increased disease symptoms with Fo5176. Conversely, Fo5176-SIX4 gene knock-out mutants (Deltasix4) had significantly reduced virulence on Arabidopsis, and this was associated with reduced fungal biomass and host jasmonate-mediated gene expression, the latter known to be essential for host symptom development. Full virulence was restored by complementation of Deltasix4 mutants with either Fo5176-SIX4 or Fol-SIX4. Thus, Fo5176-SIX4 contributes quantitatively to virulence on Arabidopsis whereas, in tomato, Fol-SIX4 acts in host specificity as both an avirulence protein and a suppressor of other race-specific resistances. The strong sequence conservation for SIX4 in F. oxysporum f. sp. lycopersici and Fo5176 suggests a recent common origin.

PubMedSearch : Thatcher_2012_Mol.Plant.Microbe.Interact_25_180
PubMedID: 21942452
Gene_locus related to this paper: fusox-a0a1d3s5h0 , fusof-f9f2k2 , fusof-f9f3l6 , fusof-f9f4n3 , fusof-f9f6t8 , fusof-f9f6v2 , fusof-f9f132 , fusof-f9f781 , fusof-f9fd72 , fusof-f9fd90 , fusof-f9fem0 , fusof-f9fhk2 , fusof-f9fiu4 , fusof-f9fj19 , fusof-f9fj20 , fusof-f9fki8 , fusof-f9fmx2 , fusof-f9fn88 , fusof-f9fnt4 , fusof-f9fpy4 , fusof-f9fvs6 , fusof-f9fwu0 , fusof-f9fxz4 , fusof-f9fzw0 , fusof-f9fzy5 , fusof-f9g2a2 , fusof-f9g3b1 , fusof-f9g5h7 , fusof-f9g5z8 , fusof-f9g6e6 , fusof-f9g6y7 , fusof-f9g7b0 , fusof-f9g797 , fusof-f9g972 , fusof-f9ga50 , fusof-f9gck4 , fusof-f9gd15 , fusof-f9gd77 , fusof-f9fgw0 , fusof-f9ftm6 , fusof-f9fji8 , fusof-f9fgw1 , fusof-f9fcz8 , fusof-f9f800 , fusof-f9f3d9 , fusof-f9gak5 , fusof-f9fsi0 , fusof-f9f4k6 , fusof-f9f4m7 , fusox-CUT , fusof-f9fvf1 , fusc4-n1s9p6 , fusof-f9g6q0 , fusox-x0h323 , fusox-x0bme4 , fusof-f9fnm6 , fusof-f9gfd3 , fusof-f9gf05 , fusof-f9fg31 , fusof-f9f774 , fusox-w9hvf0

Related information

Gene_locus fusox-a0a1d3s5h0    fusof-f9f2k2    fusof-f9f3l6    fusof-f9f4n3    fusof-f9f6t8    fusof-f9f6v2    fusof-f9f132    fusof-f9f781    fusof-f9fd72    fusof-f9fd90    fusof-f9fem0    fusof-f9fhk2    fusof-f9fiu4    fusof-f9fj19    fusof-f9fj20    fusof-f9fki8    fusof-f9fmx2    fusof-f9fn88    fusof-f9fnt4    fusof-f9fpy4    fusof-f9fvs6    fusof-f9fwu0    fusof-f9fxz4    fusof-f9fzw0    fusof-f9fzy5    fusof-f9g2a2    fusof-f9g3b1    fusof-f9g5h7    fusof-f9g5z8    fusof-f9g6e6    fusof-f9g6y7    fusof-f9g7b0    fusof-f9g797    fusof-f9g972    fusof-f9ga50    fusof-f9gck4    fusof-f9gd15    fusof-f9gd77    fusof-f9fgw0    fusof-f9ftm6    fusof-f9fji8    fusof-f9fgw1    fusof-f9fcz8    fusof-f9f800    fusof-f9f3d9    fusof-f9gak5    fusof-f9fsi0    fusof-f9f4k6    fusof-f9f4m7    fusox-CUT    fusof-f9fvf1    fusc4-n1s9p6    fusof-f9g6q0    fusox-x0h323    fusox-x0bme4    fusof-f9fnm6    fusof-f9gfd3    fusof-f9gf05    fusof-f9fg31    fusof-f9f774    fusox-w9hvf0
Gene_locus_frgt fusof-f9fj23    fusof-f9fzs6

Citations formats

Thatcher LF, Gardiner DM, Kazan K, Manners JM (2012)
A highly conserved effector in Fusarium oxysporum is required for full virulence on Arabidopsis
Mol Plant Microbe Interact 25 :180

Thatcher LF, Gardiner DM, Kazan K, Manners JM (2012)
Mol Plant Microbe Interact 25 :180