| Title : Anti-dipeptidyl-peptidase-like protein 6 encephalitis, a rare cause of reversible rapid progressive dementia and insomnia - Zhou_2020_J.Neuroimmunol_339_577114 |
| Author(s) : Zhou Q , Zhu X , Meng H , Zhang M , Chen S |
| Ref : Journal of Neuroimmunology , 339 :577114 , 2020 |
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Abstract :
Anti-dipeptidyl-peptidase-like protein 6 (DPPX) encephalitis is a rare type of autoimmune encephalitis. We present a case of a 72-year-old male with anti-DPPX encephalitis who developed rapidly progressive cognitive decline, psychiatric and sleep problems, severe abdominal pain and diarrhea. Antibodies against DPPX were positive both in serum and cerebrospinal fluid. (18)F-FDG PET-MR imaging indicated hypometabolism in the bilateral temporal lobes and thalamus. No related tumors were found, and the patient responded to immunotherapy without relapse at the 3-year follow-up. The present case enriches the understanding of the clinical, imaging manifestations and prognosis of anti-DPPX encephalitis. |
| PubMedSearch : Zhou_2020_J.Neuroimmunol_339_577114 |
| PubMedID: 31775073 |
| Gene_locus related to this paper: human-DPP6 |
Zhou Q, Zhu X, Meng H, Zhang M, Chen S (2020)
Anti-dipeptidyl-peptidase-like protein 6 encephalitis, a rare cause of reversible rapid progressive dementia and insomnia
Journal of Neuroimmunology
339 :577114
Zhou Q, Zhu X, Meng H, Zhang M, Chen S (2020)
Journal of Neuroimmunology
339 :577114