Zhu_2021_Front.Genet_12_693538

Reference

Title : Structure and Function of Pancreatic Lipase-Related Protein 2 and Its Relationship With Pathological States - Zhu_2021_Front.Genet_12_693538
Author(s) : Zhu G , Fang Q , Zhu F , Huang D , Yang C
Ref : Front Genet , 12 :693538 , 2021
Abstract :

Pancreatic lipase is critical for the digestion and absorption of dietary fats. The most abundant lipolytic enzymes secreted by the pancreas are pancreatic triglyceride lipase (PTL or PNLIP) and its family members, pancreatic lipase-related protein 1 (PNLIPRP1or PLRP1) and pancreatic lipase-related protein 2 (PNLIPRP2 or PLRP2). Unlike the family's other members, PNLIPRP2 plays an elemental role in lipid digestion, especially for newborns. Therefore, if genetic factors cause gene mutation, or other factors lead to non-expression, it may have an effect on fat digestion and absorption, on the susceptibility to pancreas and intestinal pathogens. In this review, we will summarize what is known about the structure and function of PNLIPRP2 and the levels of PNLIPRP2 and associated various pathological states.

PubMedSearch : Zhu_2021_Front.Genet_12_693538
PubMedID: 34290745
Gene_locus related to this paper: human-PNLIPRP2

Related information

Gene_locus human-PNLIPRP2
Family Pancreatic_lipase

Citations formats

Zhu G, Fang Q, Zhu F, Huang D, Yang C (2021)
Structure and Function of Pancreatic Lipase-Related Protein 2 and Its Relationship With Pathological States
Front Genet 12 :693538

Zhu G, Fang Q, Zhu F, Huang D, Yang C (2021)
Front Genet 12 :693538