1WPX

Name : Crystal structure of carboxypeptidase Y inhibitor complexed with the cognate proteinase

Revelation date : 01-Mar-2005

Family : Carboxypeptidase_S10

Gene_locus : yeast-cbpy1

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Mima, J., Hayashida, M., Fujii, T., Narita, Y., Hayashi, R., Ueda, M., Hata, Y

Ligand : Ligand in structure: Ligplot

References (7)

Title : Structure of the carboxypeptidase Y inhibitor IC in complex with the cognate proteinase reveals a novel mode of the proteinase-protein inhibitor interaction - Mima_2005_J.Mol.Biol_346_1323
Author(s) : Mima J , Hayashida M , Fujii T , Narita Y , Hayashi R , Ueda M , Hata Y
Ref : Journal of Molecular Biology , 346 :1323 , 2005
Abstract :
PubMedSearch : Mima_2005_J.Mol.Biol_346_1323
PubMedID: 15713484
Gene_locus related to this paper: yeast-cbpy1

Title : Crystallization and preliminary X-ray analysis of carboxypeptidase Y inhibitor IC complexed with the cognate proteinase - Mima_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1622
Author(s) : Mima J , Hayashida M , Fujii T , Hata Y , Hayashi R , Ueda M
Ref : Acta Crystallographica D Biol Crystallogr , 60 :1622 , 2004
Abstract :
PubMedSearch : Mima_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1622
PubMedID: 15333936
Gene_locus related to this paper: yeast-cbpy1

Title : The multiple site binding of carboxypeptidase Y inhibitor (IC) to the cognate proteinase. Implications for the biological roles of the phosphatidylethanolamine-binding protein - Mima_2003_J.Biol.Chem_278_29792
Author(s) : Mima J , Narita Y , Chiba H , Hayashi R
Ref : Journal of Biological Chemistry , 278 :29792 , 2003
Abstract :
PubMedSearch : Mima_2003_J.Biol.Chem_278_29792
PubMedID: 12791700
Gene_locus related to this paper: yeast-cbpy1

Title : Overexpression and functional characterization of a serine carboxypeptidase inhibitor (I(C)) from Saccharomyces cerevisiae - Mima_2002_J.Biochem_132_967
Author(s) : Mima J , Suzuki H , Takahashi M , Hayashi R
Ref : J Biochem , 132 :967 , 2002
Abstract :
PubMedSearch : Mima_2002_J.Biochem_132_967
PubMedID: 12473200
Gene_locus related to this paper: yeast-cbpy1

Title : N-terminal acetyl group is essential for the inhibitory function of carboxypeptidase Y inhibitor (I(C)) - Mima_2002_FEBS.Lett_532_207
Author(s) : Mima J , Kondo T , Hayashi R
Ref : FEBS Letters , 532 :207 , 2002
Abstract :
PubMedSearch : Mima_2002_FEBS.Lett_532_207
PubMedID: 12459491
Gene_locus related to this paper: yeast-cbpy1

Title : Increased proteolytic susceptibility of carboxypeptidase Y caused by modification of the disulfide zipper - Maki_2002_Biosci.Biotechnol.Biochem_66_1393
Author(s) : Maki T , Kozawa H , Mima J , Ueno H , Hayashi R
Ref : Biosci Biotechnol Biochem , 66 :1393 , 2002
Abstract :
PubMedSearch : Maki_2002_Biosci.Biotechnol.Biochem_66_1393
PubMedID: 12162566
Gene_locus related to this paper: yeast-cbpy1

Title : Amphipathic property of free thiol group contributes to an increase in the catalytic efficiency of carboxypeptidase Y - Mima_2002_Eur.J.Biochem_269_3220
Author(s) : Mima J , Jung G , Onizuka T , Ueno H , Hayashi R
Ref : European Journal of Biochemistry , 269 :3220 , 2002
Abstract :
PubMedSearch : Mima_2002_Eur.J.Biochem_269_3220
PubMedID: 12084062
Gene_locus related to this paper: yeast-cbpy1

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 1WPX Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 1WPX Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 1WPX Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 1WPX 3D, interactive encyclopedia of proteins - PROTEOPEDIA server