2ONC
Name : Crystal structure of human DPP-4 with inhibitor Alogliptin
Revelation date : 04-Mar-2008
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP4
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Feng, J., Zhang, Z., Wallace, M.B., Stafford, J.A., Kaldor, S.W., Kassel, D.B., Navre, M., Shi, L., Skene, R.J., Asakawa, T., Takeuchi, K., Xu, R., Webb, D.R., Gwaltney, S.L.
Ligand : Inhibitor Alogliptin Ligand in structure: Ligplot
References (1)
| Title : Discovery of alogliptin: a potent, selective, bioavailable, and efficacious inhibitor of dipeptidyl peptidase IV - Feng_2007_J.Med.Chem_50_2297 |
| Author(s) : Feng J , Zhang Z , Wallace MB , Stafford JA , Kaldor SW , Kassel DB , Navre M , Shi L , Skene RJ , Asakawa T , Takeuchi K , Xu R , Webb DR , Gwaltney SL, 2nd |
| Ref : Journal of Medicinal Chemistry , 50 :2297 , 2007 |
| Abstract : |
| PubMedSearch : Feng_2007_J.Med.Chem_50_2297 |
| PubMedID: 17441705 |
| Gene_locus related to this paper: human-DPP4 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 2ONC Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 2ONC Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 2ONC Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 2ONC 3D, interactive encyclopedia of proteins - PROTEOPEDIA server