| Title : Design and synthesis of pyrimidinone and pyrimidinedione inhibitors of dipeptidyl peptidase IV - Zhang_2011_J.Med.Chem_54_510 |
| Author(s) : Zhang Z , Wallace MB , Feng J , Stafford JA , Skene RJ , Shi L , Lee B , Aertgeerts K , Jennings A , Xu R , Kassel DB , Kaldor SW , Navre M , Webb DR , Gwaltney SL |
| Ref : Journal of Medicinal Chemistry , 54 :510 , 2011 |
| Abstract : |
| PubMedSearch : Zhang_2011_J.Med.Chem_54_510 |
| PubMedID: 21186796 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Discovery of alogliptin: a potent, selective, bioavailable, and efficacious inhibitor of dipeptidyl peptidase IV - Feng_2007_J.Med.Chem_50_2297 |
| Author(s) : Feng J , Zhang Z , Wallace MB , Stafford JA , Kaldor SW , Kassel DB , Navre M , Shi L , Skene RJ , Asakawa T , Takeuchi K , Xu R , Webb DR , Gwaltney SL, 2nd |
| Ref : Journal of Medicinal Chemistry , 50 :2297 , 2007 |
| Abstract : |
| PubMedSearch : Feng_2007_J.Med.Chem_50_2297 |
| PubMedID: 17441705 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Crystal structure of human dipeptidyl peptidase IV in complex with a decapeptide reveals details on substrate specificity and tetrahedral intermediate formation - Aertgeerts_2004_Protein.Sci_13_412 |
| Author(s) : Aertgeerts K , Ye S , Tennant MG , Kraus ML , Rogers J , Sang BC , Skene RJ , Webb DR , Prasad GS |
| Ref : Protein Science , 13 :412 , 2004 |
| Abstract : |
| PubMedSearch : Aertgeerts_2004_Protein.Sci_13_412 |
| PubMedID: 14718659 |
| Gene_locus related to this paper: human-DPP4 |
| Title : N-linked glycosylation of dipeptidyl peptidase IV (CD26): effects on enzyme activity, homodimer formation, and adenosine deaminase binding - Aertgeerts_2004_Protein.Sci_13_145 |
| Author(s) : Aertgeerts K , Ye S , Shi L , Prasad SG , Witmer D , Chi E , Sang BC , Wijnands RA , Webb DR , Swanson RV |
| Ref : Protein Science , 13 :145 , 2004 |
| Abstract : |
| PubMedSearch : Aertgeerts_2004_Protein.Sci_13_145 |
| PubMedID: 14691230 |