3F8S

Name : Crystal structure of dipeptidyl peptidase IV in complex with inhibitor

Revelation date : 23-Jun-2009

Family : DPP4N_Peptidase_S9

Gene_locus : human-DPP4

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Ammirati, M.J., Liu, S., Piotrowski, D.W.

Ligand :

References (1)

Title : (3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrr olidin-2-yl]-methanone: a potent, selective, orally active dipeptidyl peptidase IV inhibitor - Ammirati_2009_Bioorg.Med.Chem.Lett_19_1991
Author(s) : Ammirati MJ , Andrews KM , Boyer DD , Brodeur AM , Danley DE , Doran SD , Hulin B , Liu S , McPherson RK , Orena SJ , Parker JC , Polivkova J , Qiu X , Soglia CB , Treadway JL , VanVolkenburg MA , Wilder DC , Piotrowski DW
Ref : Bioorganic & Medicinal Chemistry Lett , 19 :1991 , 2009
PubMedID: 19275964
Gene_locus related to this paper: human-DPP4

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 3F8S Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 3F8S Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 3F8S Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 3F8S 3D, interactive encyclopedia of proteins - PROTEOPEDIA server