4A5S
Name : Crystal Structure of human DDP4 in complex with a novel heterocyclic DPP4 inhibitor
Revelation date : 08-Feb-2012
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP4
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Ostermann, N., Kroemer, M., Zink, F., Gerhartz, B., Sutton, J.M., Clark, S.E., Dunsdon, S.J., Fenton, G., Fillmore, A., Harris, N.V., Higgs, C., Hurley, C.A., Krintel, S.L., MacKenzie, R.E., Duttaroy, A., Gangl, E., Maniara, W., Sedrani, R., Namoto, K., Sirockin, F., Trappe, J., Hassiepen, U., Baeschlin, D.K.
Ligand :
References (1)
| Title : Novel heterocyclic DPP-4 inhibitors for the treatment of type 2 diabetes. - Sutton_2012_Bioorg.Med.Chem.Lett_22_1464 |
| Author(s) : Sutton JM , Clark DE , Dunsdon SJ , Fenton G , Fillmore A , Harris NV , Higgs C , Hurley CA , Krintel SL , Mackenzie RE , Duttaroy A , Gangl E , Maniara W , Sedrani R , Namoto K , Ostermann N , Gerhartz B , Sirockin F , Trappe J , Hassiepen U , Baeschlin DK |
| Ref : Bioorganic & Medicinal Chemistry Lett , 22 :1464 , 2012 |
| Abstract : Sutton_2012_Bioorg.Med.Chem.Lett_22_1464 |
| ESTHER : Sutton_2012_Bioorg.Med.Chem.Lett_22_1464 |
| PubMedSearch : Sutton_2012_Bioorg.Med.Chem.Lett_22_1464 |
| PubMedID: 22177783 |
| Gene_locus related to this paper: human-DPP4 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 4A5S Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 4A5S Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 4A5S Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 4A5S 3D, interactive encyclopedia of proteins - PROTEOPEDIA server