4N8E
Name : DPP4 complexed with compound 12a
Revelation date : 12-Feb-2014
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP4
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Ostermann, N., Zink, F., Kroemer, M.
Ligand : Inhibitor CHEMBL3112966 Ligand in structure: Ligplot
References (1)
| Title : Discovery of C-(1-aryl-cyclohexyl)-methylamines as selective, orally available inhibitors of dipeptidyl peptidase IV - Namoto_2014_Bioorg.Med.Chem.Lett_24_731 |
| Author(s) : Namoto K , Sirockin F , Ostermann N , Gessier F , Flohr S , Sedrani R , Gerhartz B , Trappe J , Hassiepen U , Duttaroy A , Ferreira S , Sutton JM , Clark DE , Fenton G , Beswick M , Baeschlin DK |
| Ref : Bioorganic & Medicinal Chemistry Lett , 24 :731 , 2014 |
| Abstract : |
| PubMedSearch : Namoto_2014_Bioorg.Med.Chem.Lett_24_731 |
| PubMedID: 24439847 |
| Gene_locus related to this paper: human-DPP4 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 4N8E Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 4N8E Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 4N8E Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 4N8E 3D, interactive encyclopedia of proteins - PROTEOPEDIA server