Name : Crystal structure of human LP_PLA2 in complex with Darapladib

Revelation date : 15-Jun-2016

Family : PAF-Acetylhydrolase

Gene_locus : human-PLA2G7

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Liu, Q.F., Chen, X.D., Chen, W.Y., Yuan, X.J., Su, H.X., Shen, J.H., Xu, Y.C.

Ligand : Inhibitor Darapladib Ligand in structure: Ligplot

References (1)

Title : Structural and Thermodynamic Characterization of Protein-Ligand Interactions Formed between Lipoprotein-Associated Phospholipase A2 and Inhibitors - Liu_2016_J.Med.Chem_59_5115
Author(s) : Liu Q , Chen X , Chen W , Yuan X , Su H , Shen J , Xu Y
Ref : Journal of Medicinal Chemistry , 59 :5115 , 2016
Abstract :
PubMedSearch : Liu_2016_J.Med.Chem_59_5115
PubMedID: 27078579
Gene_locus related to this paper: human-PLA2G7

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server


PDB-Sum : 5I9I Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 5I9I Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 5I9I Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 5I9I 3D, interactive encyclopedia of proteins - PROTEOPEDIA server