Name : Human DPP4 in complex with a novel 5,5,6-tricyclic pyrrolidine inhibitor
Revelation date : 11-May-2016
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP4
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Scapin, G
Title : The discovery of novel 5,6,5- and 5,5,6-tricyclic pyrrolidines as potent and selective DPP-4 inhibitors - Cox_2016_Bioorg.Med.Chem.Lett_26_2622 |
Author(s) : Cox JM , Chu HD , Kuethe JT , Gao YD , Scapin G , Eiermann G , He H , Li X , Lyons KA , Metzger J , Petrov A , Wu JK , Xu S , Sinha-Roy R , Weber AE , Biftu T |
Ref : Bioorganic & Medicinal Chemistry Lett , 26 :2622 , 2016 |
Abstract : |
PubMedSearch : Cox_2016_Bioorg.Med.Chem.Lett_26_2622 |
PubMedID: 27106708 |
Gene_locus related to this paper: human-DPP4 |
PDB-Sum : 5ISM Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 5ISM Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 5ISM Structural Classification Of Protein - SCOP server
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