5JAH
Name : Exploitation of a novel binding pocket in human Lipoprotein-associated Phospholipase A2 (Lp-PLA2) discovered through X-Ray fragment screening
Revelation date : 25-May-2016
Family : PAF-Acetylhydrolase
Gene_locus : human-PLA2G7
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Day, P.J.
Ligand : Ligand in structure: Ligplot
References (1)
| Title : Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening - Woolford_2016_J.Med.Chem_59_5356 |
| Author(s) : Woolford AJ , Pero JE , Aravapalli S , Berdini V , Coyle JE , Day PJ , Dodson AM , Grondin P , Holding FP , Lee LY , Li P , Manas ES , Marino J, Jr. , Martin AC , McCleland BW , McMenamin RL , Murray CW , Neipp CE , Page LW , Patel VK , Potvain F , Rich S , Rivero RA , Smith K , Somers DO , Trottet L , Velagaleti R , Williams G , Xie R |
| Ref : Journal of Medicinal Chemistry , 59 :5356 , 2016 |
| Abstract : |
| PubMedSearch : Woolford_2016_J.Med.Chem_59_5356 |
| PubMedID: 27167608 |
| Gene_locus related to this paper: human-PLA2G7 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 5JAH Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 5JAH Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 5JAH Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 5JAH 3D, interactive encyclopedia of proteins - PROTEOPEDIA server