5LYY
Name : Fragment-based inhibitors of human Lipoprotein associated Phospholipase A2 CHEMBL3908555
Revelation date : 21-Dec-2016
Family : PAF-Acetylhydrolase
Gene_locus : human-PLA2G7
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Woolford, A.J-A, Day, P.J.
Ligand : Inhibitor CHEMBL3908555 Ligand in structure: Ligplot
References (1)
| Title : Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) - Woolford_2016_J.Med.Chem_59_10738 |
| Author(s) : Woolford AJ , Day PJ , Beneton V , Berdini V , Coyle JE , Dudit Y , Grondin P , Huet P , Lee LY , Manas ES , McMenamin RL , Murray CW , Page LW , Patel VK , Potvain F , Rich SJ , Sang Y , Somers DO , Trottet L , Wan Z , Zhang X |
| Ref : Journal of Medicinal Chemistry , 59 :10738 , 2016 |
| Abstract : |
| PubMedSearch : Woolford_2016_J.Med.Chem_59_10738 |
| PubMedID: 27933945 |
| Gene_locus related to this paper: human-PLA2G7 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 5LYY Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 5LYY Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 5LYY Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 5LYY 3D, interactive encyclopedia of proteins - PROTEOPEDIA server