5SYN

Name : Cocrystal structure of the human acyl protein thioesterase 2 with an isoform-selective inhibitor, ML349

Revelation date : 26-Oct-2016

Family : LYsophospholipase_carboxylesterase

Gene_locus : human-LYPLA2

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Labby, K.J., Stuckey, J.A., Meagher, J.L., Won, S.J., Martin, B.R.

Ligand :

References (1)

Title : Molecular Mechanism for Isoform-Selective Inhibition of Acyl Protein Thioesterases 1 and 2 (APT1 and APT2) - Won_2016_ACS.Chem.Biol_11_3374
Author(s) : Won SJ , Davda D , Labby KJ , Hwang SY , Pricer R , Majmudar JD , Armacost KA , Rodriguez LA , Rodriguez CL , Chong FS , Torossian KA , Palakurthi J , Hur ES , Meagher JL , Brooks CL, 3rd , Stuckey JA , Martin BR
Ref : ACS Chemical Biology , 11 :3374 , 2016
PubMedID: 27748579
Gene_locus related to this paper: human-LYPLA1 , human-LYPLA2

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 5SYN Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 5SYN Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 5SYN Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 5SYN 3D, interactive encyclopedia of proteins - PROTEOPEDIA server