5UXZ

Name : X-ray crystal structure of Halotag (Haloalkane dehalogenase) bound to the P9 benzothiadiazole fluorogenic ligand

Revelation date : 08-Mar-2017

Family : Haloalkane_dehalogenase-HLD2

Gene_locus : rhoso-halo1

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Depositors: Dunham, N.P., Boal, A.K. Mutations of rhoso-halo1: L47V, S58T, D78G, Y87F, L88M, C128F, A155T, E160K, A167V, A172T, K175M, C176G, K195N, A224E, N227D, E257K, T264A, H272N, Y273L

Ligand : Inhibitor P9-benzothiadiazole Ligand in structure: Ligplot

References (1)

Title : The Cation-pi Interaction Enables a Halo-Tag Fluorogenic Probe for Fast No-Wash Live Cell Imaging and Gel-Free Protein Quantification - Liu_2017_Biochemistry_56_1585
Author(s) : Liu Y , Miao K , Dunham NP , Liu H , Fares M , Boal AK , Li X , Zhang X
Ref : Biochemistry , 56 :1585 , 2017
Abstract :
PubMedSearch : Liu_2017_Biochemistry_56_1585
PubMedID: 28221782
Gene_locus related to this paper: rhoso-halo1

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 5UXZ Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 5UXZ Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 5UXZ Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 5UXZ 3D, interactive encyclopedia of proteins - PROTEOPEDIA server