Name : X-ray crystal structure of Halotag (Haloalkane dehalogenase) bound to the P9 benzothiadiazole fluorogenic ligand
Revelation date : 08-Mar-2017
Family : Haloalkane_dehalogenase-HLD2
Gene_locus : rhoso-halo1
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Depositors: Dunham, N.P., Boal, A.K. Mutations of rhoso-halo1: L47V, S58T, D78G, Y87F, L88M, C128F, A155T, E160K, A167V, A172T, K175M, C176G, K195N, A224E, N227D, E257K, T264A, H272N, Y273L
Ligand : Inhibitor P9-benzothiadiazole Ligand in structure: Ligplot
Title : The Cation-pi Interaction Enables a Halo-Tag Fluorogenic Probe for Fast No-Wash Live Cell Imaging and Gel-Free Protein Quantification - Liu_2017_Biochemistry_56_1585 |
Author(s) : Liu Y , Miao K , Dunham NP , Liu H , Fares M , Boal AK , Li X , Zhang X |
Ref : Biochemistry , 56 :1585 , 2017 |
Abstract : |
PubMedSearch : Liu_2017_Biochemistry_56_1585 |
PubMedID: 28221782 |
Gene_locus related to this paper: rhoso-halo1 |
PDB-Sum : 5UXZ Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 5UXZ Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 5UXZ Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 5UXZ 3D, interactive encyclopedia of proteins - PROTEOPEDIA server