P9-benzothiadiazole
Fluorogenic Probe for Fast No-Wash Live Cell Imaging and Gel-Free Protein Quantification
General
Type : Sulfur Compound, Fluorescent Probe, Thiadiazol, Sulfonyl
Chemical_Nomenclature : 2-[[7-(dimethylamino)-2,1,3-benzothiadiazol-4-yl]sulfonyl-methylamino]-N-(6-hydroxyhexyl)acetamide
Canonical SMILES : CN(C)C1=CC=C(C2=NSN=C12)S(=O)(=O)N(C)CC(=O)NCCCCCCO
InChI : InChI=1S\/C17H27N5O4S2\/c1-21(2)13-8-9-14(17-16(13)19-27-20-17)28(25,26)22(3)12-15(24)18-10-6-4-5-7-11-23\/h8-9,23H,4-7,10-12H2,1-3H3,(H,18,24)
InChIKey : FAIBIJWJUPXKNF-UHFFFAOYSA-N
Other name(s) : 8PM || N~2~-{[7-(Dimethylamino)-2,1,3-Benzothiadiazol-4-Yl]sulfonyl}-N-Hexyl-N~2~-Methylglycinamide
MW : 429.55
Formula : C17H27N5O4S2
CAS_number :
PubChem : 124220277
UniChem : FAIBIJWJUPXKNF-UHFFFAOYSA-N
Target
Families : P9-benzothiadiazole ligand of proteins in family
Haloalkane_dehalogenase-HLD2
Structure :
5UXZ
Protein :
rhoso-halo1
References (1)
| Title : The Cation-pi Interaction Enables a Halo-Tag Fluorogenic Probe for Fast No-Wash Live Cell Imaging and Gel-Free Protein Quantification - Liu_2017_Biochemistry_56_1585 |
| Author(s) : Liu Y , Miao K , Dunham NP , Liu H , Fares M , Boal AK , Li X , Zhang X |
| Ref : Biochemistry , 56 :1585 , 2017 |
| Abstract : |
| PubMedSearch : Liu_2017_Biochemistry_56_1585 |
| PubMedID: 28221782 |
| Gene_locus related to this paper: rhoso-halo1 |