6R8Q
Name : Structure of the human Wnt deacylase Notum in complex with a benzotriazole fragment JV5
Revelation date : 08-May-2019
Family : Pectinacetylesterase-Notum
Gene_locus : human-NOTUM
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Atkinson, B.N., Steadman, D., Zhao, Y., Sipthorp, J., Vecchia, L., Ruza, R.R., Jegnathan, F., Lines, G., Frew, S., Monaghan, A., Kjaer, S., Bictash, M., Jones, Y., Fish, P.V.
Ligand :
References (1)
| Title : Discovery of 2-phenoxyacetamides as inhibitors of the Wnt-depalmitoleating enzyme NOTUM from an X-ray fragment screen - Atkinson_2019_Medchemcomm_10_1361 |
| Author(s) : Atkinson BN , Steadman D , Zhao YG , Sipthorp J , Vecchia L , Ruza RR , Jeganathan F , Lines G , Frew S , Monaghan A , Kjaer S , Bictash M , Jones Y , Fish PV , Zhao Y , Jones EY |
| Ref : Medchemcomm , 10 :1361 , 2019 |
| Abstract : Atkinson_2019_Medchemcomm_10_1361 |
| ESTHER : Atkinson_2019_Medchemcomm_10_1361 |
| PubMedSearch : Atkinson_2019_Medchemcomm_10_1361 |
| PubMedID: 31534655 |
| Gene_locus related to this paper: human-NOTUM |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 6R8Q Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 6R8Q Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 6R8Q Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 6R8Q 3D, interactive encyclopedia of proteins - PROTEOPEDIA server